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Generical name: pegfilgrastim”PEG-fil-GRAS-tim” PEG-fil-GRAS-tim
The brand names are: Fulphila, Fylnetra, Neulasta, Neulasta Onpro Kit, Nyvepria,… display the eight brands
Drug class: colony-stimulating factors

What is Udenyca?

Udenyca helps to stop the development of neutropenia (an absence of white blood cells in certain cases) caused by chemotherapy. Udenyca is a protein that promotes the expansion of cells called white blood cells. These cells aid your body in fighting the effects of Udenyca can also be employed for other purposes that are not covered in this guideline for medication.

Side effects of Udenyca

Contact emergency medical assistance. If you notice symptoms that indicate an allergic reaction, such as hives and itchy skin, itching, sweating, and tingling sensations, dizziness, rapid heartbeats, wheezing or breathing difficulties, or swelling of your lips, face, and tongue,

The condition is known as capillary leak syndrome, which can occur in a very rare but severe adverse effect associated with pegfilgrastim. Contact your physician immediately if you are experiencing symptoms of this condition. These could include decreased urine output, fatigue, and lightheadedness, as well as breathing difficulties, abrupt swelling, puffiness, or feeling full.

Udenyca can cause severe adverse effects. Consult your physician immediately in the event that you experience:

  • A sudden and severe pain is felt in the left upper abdomen, spreading all the way to your shoulder.
  • Abrupt and intense discomfort in your chest, back, stomach, or stomach;
  • Persistent or constant pain within your body;
  • Fever, tiredness;
  • Breathlessness and rapid breathing.
  • Easily bleeding, unusual bruising spots of red or purple under the skin
  • Swelling, bruising, or a hard lump in the area where the medication was injected or
  • Kidney problems: no or little urine, dark or pink urine, swelling on your legs, face, or around your ankles

The cancer treatment may be delayed or completely stopped in the event of certain adverse consequences.

Common adverse effects of udenyca could include:

  • Bone pain or
  • Discomfort in your arms or legs.

This isn't a complete list of possible side effects, and other side effects could occur. Contact your physician for advice regarding medical effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Similar or related drugs

Neulasta, filgrastim, Zarxio, Neupogen, pegfilgrastim, and Granix


Follow the instructions on your prescription label and the package. Be sure to inform your health care providers about your allergies, medical issues, and any other medications you take.

Prior to use this drug

It is not recommended to use Udenyca if you are allergic to Udenyca or filgrastim (Neupogen).

Speak to your doctor if you have ever suffered from:

  • Sickle cell disorder;
  • Kidney disease;
  • Acute myeloidleukemia;
  • Radiation treatment;
  • Myelodysplastic disorder (also referred to as "preleukemia"); or
  • A allergy to latex

Treatment using Fulphila and radiation, with the option of chemotherapy without or with lung cancer, means that there is a chance that you will develop a blood disorder or an abnormality in your blood (leukemia). Consult your physician about the possibility.

Inform your doctor if you are nursing or pregnant.

How to take Udenyca?

Follow the instructions on the prescription label and read the medication guide or instructions sheets. Make sure you use the medicine as prescribed. Udenyca should not be taken within 14 days of or within 24 hours following the time you have received chemotherapy. Udenyca is injected underneath the skin. The healthcare professional may instruct you on the proper use of the drug on your own.

Be sure to read and adhere to any instructions for use that are included in your medication. Consult your physician or pharmacist to clarify any instructions. You should prepare your injection only when you are ready to administer it. Don't use it when the medication appears cloudy, changes color, or contains particles. Consult your pharmacist about the latest medication. Your blood might need to be checked frequently. Follow the directions of your physician before administering Udenyca to the child weighing below the weight of 99 lbs (45 kg). The correct dosage for children of such size is not easily determined with the syringe prefilled. It is possible that you will require medical tests to aid your doctor in determining what time frame to treat you with Udenyca.

Keep the filled syringe in its original packaging within the fridge, away from light. Do not shake or freeze. The syringe should be removed from the refrigerator and allowed to cool to temperatures of around 30 minutes before injecting the dose. If the syringe is frozen, you can thaw it by placing it in the fridge. Avoid using any syringes that have had to be frozen more than a few times.

Don't utilize the Neulasta or Udenyca syringe, which was stored at room temperature for more than 48 hours. Don't make use of the Fylnetra, Fulphila, or Stimufend Syringe that is kept on the counter at room temperature for more than 72 hours. Don't make use of any Ziextenzo syringe that is stored in a room for more than 5 days. This Neulasta Onpro Injector is a specially designed device placed on the skin to deliver the Udenyca dosage at a certain time. You'll need to put on the product for a period of 27 hours prior to the start of the dose. The dose that you have scheduled will be removed from the device gradually over a 45-minute period.

Maintain Neulasta onpro chilled until you are able to put it on. Do not use a Neulasta Onpro device that has been kept in the refrigerator for more than twelve hours. Don't use a Nys Pre-filled syringe that has been kept out of the refrigerator for more than 15 days. When wearing Neulasta Onpro, a caregiver or you should test the device to make sure it's functioning properly. The syringes and Onpro injector are intended for use once only. It is best to dispose of it after one usage, regardless of whether there's still medicine within. Make use of a needle and syringe just once, and then put them in a puncture-proof "sharps" container. Be sure to follow the laws of your state or city on how to dispose of the container. Keep it out of the reach of pets and children.

What happens if I miss the dose?

Consult your physician when you have missed an injection or are having issues using your Neulasta Onpro machine.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact for help at the Poison Help Line at 1-800-222-1222.

The signs of an overdose include bone pain, discomfort when you breathe or feel short of breath in a reclining position, wheezing, struggling to breathe, coughing with foamy mucus, cold skin that feels clammy, anxiety, and fast heartbeats.

What should be avoided?

While using Neulasta Onpro Beware of traveling or driving machines while wearing the device.

Interaction with other drugs

Other medications may also influence Udenyca, such as medications that are prescribed and available over the counter, vitamins, and herbal products. Discuss with your doctor the medicines you are currently taking as well as any medications you are about to start or stop taking.