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Generic name: meropenem and vaborbactam [MER-oh-PEN-em-and-VA-bor-BAK-tam]
Drug class: carbapenems and beta-lactamase inhibitors

What is Vabomere?

Vabomeres are antibiotics that fight against bacteria.Vabomere is a combination medication designed to treat urinary tract infections that affect adults.Vabomere is also employed for other purposes that are not covered in this guideline.

Side effects of Vabomere

Seek medical attention immediately. If you notice symptoms that indicate an allergic reaction (hives and breathing problems or swelling of your throat or face) or an extreme skin reaction (fever and burning or sore throats, irritation in your eyes, pain in the skin, and an ailment or redness that causes blisters as well as peeling),

Vabomere could cause severe adverse effects.Should you experience:

  • Extreme stomach pains, diarrhea that is bloody or watery
  • A seizure (convulsions);
  • Sores or white patches of your throat or mouth (yeast infection or "thrush");
  • Numbness, numbness, or severe tingling or
  • Unusual bleeding or unusual bleeding

Common adverse effects of Vabomere could include:

  • Headache;
  • Diarrhea;
  • An irritation or swelling in the area where the medicine was injected.

This list does not cover all possible side effects. Others could happen. Contact your doctor for advice regarding medical effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Similar or related drugs

Amoxicillin, Doxycycline, Ciprofloxacin, Augmentin, Levofloxacin, and Ceftriaxone


Before receiving Vabomere, inform your doctor whether you have any allergies to any antibiotic medication.

Before you take this drug

You might not be able to take this medication if you have previously experienced an allergy reaction to antibiotics such as:

  • Meropenem or vaborbactam
  • Amoxicillin, ampicillin, Augmentin, Timentin, Unasyn, Zosyn
  • Dicloxacillin, nafcillin, oxacillin, ticarcillin,
  • Any antibiotic, penicillin.

To be sure Vabomere is suitable for you, inform your doctor if you previously had:

  • An allergy to the antibiotic cephalosporin (cephalexin or cefdinir, Keflex, Omnicef, and others);
  • A head injury or brain tumor;
  • Epilepsy or another seizure;
  • Kidney disease (or those who are taking dialysis).

It isn't known if this medication could cause harm to a baby who is not yet born. Consult your physician if you are expecting.

Meropenem and vaborbactam are able to be found in the milk of a nursing baby, but their consequences for nursing infants aren't known. Inform your doctor if you are breastfeeding.

How to take Vabomere?

Follow all the instructions on the prescription label. Don't use Vabomere in greater or less quantities or for longer than the recommended time.Vabomere is injected into a vein via an IV. It is possible to be taught how to administer an IV at home. Don't give yourself the medicine if you do not know how to apply the injection correctly. Eliminate IV tubing, needles, and other equipment that are used.

Vabomere is generally administered every 8–12 hours for a period of up to 14 days. This medication must be administered slowly, and infusions can take up to 3 hours to be completed.Vabomere is a medication in powder form that needs to be mixed with liquid (diluent) and then further diluted prior to use. If you're using injectables yourself, make sure that you are aware of how to blend and preserve the medication.

The mixture that has been diluted must be used within four hours if it is kept at room temperature. If you keep your IV bags in the fridge, you should use them immediately after 22 hours. Do not put it in the freezer.

The single-use container (bottle) made up of meropenem or vaborbactam powder is intended for one-time use only. Dispose of it after just one use, regardless of whether there is medicine in the bottle.Do not mix any injectable medicines within the same IV bag or tubing that you use to administer the Vabomere injection.

Get rid of any unneeded medicine that remains within the intravenous bag following the infusion. Don't save it for future use.

Make sure to take this medicine for the prescribed duration. Your symptoms may worsen prior to the infection being completely removed. The absence of doses can increase the chance of developing a new infection that is intolerant of antibiotics. Vabomere cannot cure the symptoms of a viral illness like the flu or the typical cold or flu.

The kidney function of your patient may require a check during the course of taking this medication.Store powder that is not mixed at room temperature away from heat and moisture.

Make use of an empty needle and syringe just once. Be sure to follow any local or state regulations regarding the disposal of needles and syringes that are no longer in use. Make sure you use puncture-proof "sharps" disposal containers (ask your pharmacist for one and how to dispose of them). Keep the container out of reach of pets and kids.

What happens if I miss a dose?

Take the missed dose immediately after you recall. If it is close to time for your next dose, do not attempt to make up the difference with extra medication. If a missed dose occurs, don't double up on medication in an attempt to make up for what was missed by taking multiple pills at once.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Vabomere could cause headaches, confusion, and other effects that could affect your ability to think or react. Be cautious when driving or engaging in any activity that requires you to stay vigilant.

The use of antibiotics can trigger diarrhea and could be a sign of a new infection. If you are experiencing diarrhea that is swollen or bloody, consult your doctor. Do not take any anti-diarrhea medications unless your doctor has told you to.

Interaction with other drugs

Discuss with your physician all the medicines you are currently taking and all you are about to start or stop taking, particularly:

This list isn't complete. Other drugs can be incompatible with vaborbactam and meropenem, such as prescription and over-the-counter medications, vitamins, and herbal products. There are not all interactions included in this guideline for medication.