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Aristada Injection

Generic Name: Aripiprazole lauroxil (injection) [AR-i-PIP-ra-zole]
The Brand Name is Aristada.
Drug Class: Adtypical antipsychotics

What is Aristada?

Aristada (aripiprazole) is used by adults to treat symptoms that are associated with schizophrenia (a mental illness that can cause abnormal or disturbed thinking, a loss of interest in the world, and heightened or inappropriate emotions).Aristada Initio is combined with oral aripiprazole for the purpose of starting or stopping Aristada.Aristada belongs to a category of medications known as antipsychotics that are atypical. Aripiprazole is a medication that alters the activity of certain neurochemicals in the brain.

Take Aristada according to the prescription of your physician. If you have already been taking antipsychotic drugs, you may have to use Aristada for a brief period of time. Don't alter your dosage or frequency of doses without consulting your physician.

If you've never taken Aristada, you might have to take aripiprazole through the mouth (in tablets in liquid or tablet form) before receiving the first dose.You might need to keep taking aripiprazole orally for a period of up to three weeks following the first injection. Follow the instructions of your doctor for dosing with care.Aristada is an injection into a muscle. The healthcare professional will administer this injection every 4–8 weeks. The doctor can modify your dose or dosage schedule.

The blood sugar level of your body will need to be tested regularly, and you may require additional medical tests.


Aristada is not approved for use by patients with psychotic issues that are related to dementia. Aripiprazole can increase the likelihood of death for those with dementia-related psychosis.

Before You Take This Drug

It is not recommended to treat with Aristada if you have an allergy to the drug aripiprazole.Speak to your doctor if you haven't used Aristada.

Aripiprazole could raise the chance of death in people with psychosis related to dementia. It is not permitted for this purpose.To make sure that this medicine is suitable for you, inform your physician if you've previously had:

  • An issue with receiving an injection within the buttocks or in the arm;
  • The heart or stroke, stroke or stroke
  • Blood pressure, or high blood pressure,
  • Diabetes, high blood sugar (in a family member of you);
  • A seizure;
  • High cholesterol or triglycerides
  • Dehydration
  • Low white blood cell (WBC) counts of white blood cells (WBC)

Utilizing antipsychotic medications within the last 3 months of pregnancy could create serious health issues for the baby. Tell your doctor right away if you get pregnant. Do not stop taking the medication without a doctor's recommendation.

If you're expecting and you are a registered mother, your name could be included on the registry for pregnancy to monitor any effects of Aripiprazole on the infant.Consult your doctor for advice on whether it is safe to breastfeed while taking this medication.

Details On Dosage

Usual Adult Dose for Schizophrenia:

Aripiprazole Lauroxil Extended-Release IM Suspension:
-Initial dose:
Patients who are stable with oral aripiprazole 10 mg/day: 441 milligrammes intramuscular via gluteal or deltoid injections ONCE, plus Aripiprazole Lauroxil 675 mg IM ONCE, or aripiprazole 10 mg taken orally every day for 21 consecutive days.
Patients who are stable on oral aripiprazole 15 mg/day of IR initial dose (662 mg IM by gluteal injection once) plus aripiprazole (675 mg IM ONCE) or aripiprazole (15 mg) taken orally every day for 21 days
Patients who are stable on an oral aripiprazole daily dose of at least 20 mg (882 mg IM) by gluteal injections ONCE, Aripiprazole Lauroxil 675 mg ONCE, or aripiprazole intramuscular once every day up to 21 days
Maintenance doses: 441 mg, 662 mg, or 882 mg IM every month; 882 mg IM between 4 and 6 weeks; or 1064 mg of IM every two months. The medicine should not be given within 14 days of the last injection.
Initiated treatment resumption: initial 675 mg of IM orally and 30 mg of Aripiprazole IR orally
Before starting therapy using extended-release I'M formulations, the tolerability of the drug should be assessed using oral formulations. It could take between 2 and 4 weeks to assess how well the drug is tolerated due to the short half-life of aripiprazole.
The first dose of the extended-release IM formulation should be given on the same day as the initiation or re-initiation dose; providers should avoid injecting both formulations in the same deltoid or gluteal muscle.
Adjustments to the dosage regimen (including the addition of oral supplementation) are required in the event of missed doses.

What Happens If I Miss a Dose?

Consult your physician for treatment. If you do not make an appointment to receive your aripiprazole injection,

What Happens If I Miss a Dose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

The symptoms of an overdose can include sleepiness as well as shallow or weak breathing, nausea, fatigue, aggression, and tremors. Other symptoms include confusion, tremors, a tremors slow, or unsteady heartbeat, a lightheaded sensation, high blood pressure, seizures, or even fainting.

What Should Be Avoided?

Do not get up too quickly from a lying or sitting position, as you could be dizzy. Avoid driving or doing any hazardous activity until you are aware of what the effect of this medication will be on your body. Drowsiness, dizziness, or confusion can lead to accidents, falls, or even serious injuries.Avoid drinking or consuming alcohol. Dangerous side effects may be experienced.

Avoid getting dehydrated or too hot during your workout, in the heat, or simply in the absence of enough fluids. Drink plenty of fluids while you take Aristada.

Avoid the sun and tanning beds. Be sure to wear protective attire and sunblock (SPF 30 or more) whenever you're outside.

Side Effects Of Aristada

Contact a medical professional immediately. Get medical attention immediately if you show symptoms that are warning signs of allergic reactions, including hives, trouble breathing, and swelling of your lips, face, and tongue.

The use of high doses or long periods of Aristada could cause serious movement disorders that could not be reversed. The longer you are using this medication, the more probable it is that you will be affected by this condition, particularly if you're female or an older adult.

You might experience more sexual urges, unusual cravings towards gambling, or any other intense desires while taking this medication.See your doctor to determine if this is the case. Aristada may cause serious side effects.Consult your physician immediately If you notice:

  • Uncontrolled muscle movements in your facial muscles (chewing or smacking your lips, mouth movement, frowning, blinking, or eye movements);
  • Experiencing unusually cold or hot
  • Difficulty swallowing
  • A seizure;
  • Feeling like you could feel like you might (even in bed);
  • Extreme nervous system reactions extremely strenuous (rigid) muscles and extremely high fever sweating, confusion, irregular or fast heartbeats, tremors, or tremors that feel like you're going to pass out;
  • Lower blood-cell counts (fever, chills) fatigue, mouth sores, skin sores, mild bleeding, unusual bruising, pale skin, cold hands and feet, and feeling lightheaded and short of breath.
  • Indications of signs such as chills, fever, sore throat, body aches, uncharacteristic fatigue, loss of appetite, bleeding or bruising,
  • Blood sugar levels are high, increasing thirst and more frequent urination; the mouth is dry; and there's a fruity smell.

Common Aristada adverse effects could include:

  • Feeling agitated;
  • Pain where the medicine was injected
  • Weight gain

This isn't a complete list of possible side effects, and others could happen.Talk to your physician for medical advice about the effect. If you have any concerns, report the allergic reactions or symptoms to the FDA by calling 1-800-FDA-1088.

Interaction With Other Drugs

It is sometimes not safe to take certain medications simultaneously. Certain drugs may affect the blood levels of other medications you take, which could create side effects or render the medications less effective.

Inform your doctor about all the medications you take. Aripiprazole can be affected by a variety of drugs, in particular:

  • Blood pressure medication;
  • Benzodiazepine sedatives such as Valium, Klonopin, or Xanax;
  • Bronchodilator asthma medicine;
  • Cold or allergy medication (Benadryl and others);
  • medication to treat the symptoms of an overactive bladder;
  • medication for treating those suffering from Parkinson's disease.
  • Medicine to treat stomach disorders, motion sickness, or IBS.

This isn't a complete list, and a variety of other medications could be incompatible with Aripiprazole. This includes prescription and over-the-counter drugs, vitamins, and herbal supplements. There are many possible interactions between drugs that are listed here.



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