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Aristada

Generic name: aripiprazole lauroxil (injection) [AR-i-PIP-ra-zole]
Name of brand: Aristada
Drug class: atypical antipsychotics

What is Aristada?

Aristada (aripiprazole) is a medication used by adults to treat the signs that are associated with schizophrenia (a mental illness that results in irregular or erratic thinking, a lack of interest in daily activities, and inappropriate or strong emotions).Aristada Initio is combined with oral aripiprazole for the purpose of starting or re-starting Aristada.Aristada is a member of a group of medications known as antipsychotics that are atypical. Aripiprazole is a medication that alters the action of a few neurochemicals in the brain.

Warnings

Aristada is not a drug approved for use by older adults suffering from psychotic illnesses that are related to dementia. Aripiprazole can raise the chance of dying in patients with dementia-related psychosis.

Before you take this drug

It is not recommended to treat with Aristada when you have an allergy to Aripiprazole.Inform your doctor if you haven't used Aristada.Aripiprazole could raise the chance of death for people with psychosis related to dementia. However, it isn't recommended for use in this situation.

To ensure that this medication is suitable for you, inform your doctor if you've previously had:

  • A problem when receiving an injection within the buttocks or arm;
  • Heart disease heart disease, stroke, or stroke
  • Blood pressure, or high blood pressure,
  • High blood sugar levels, diabetes (in a family member of you);
  • A seizure;
  • High cholesterol or triglycerides
  • Dehydration
  • Low white blood cell (WBC) counts of white blood cells (WBC).

Utilising antipsychotic medications within the last 3 months of pregnancy can create serious health issues for the baby.Notify your doctor immediately if you suspect being pregnant. Don't stop taking the medicine without consulting with your doctor.If you're expecting, then your name might be included on the registry for pregnancy to monitor how aripiprazole affects the infant.Consult your doctor to determine whether it is safe to breastfeed while taking this medicine.

Similar/related drugs

Caplyta, quetiapine, Abilify, Seroquel, aripiprazole, risperidone, and olanzapine

How to take Aristada?

Take Aristada according to the prescription of your physician. If you have already been taking antipsychotic drugs, you may need to continue using Aristada for a brief period of time. Don't alter your dosage or frequency of doses without a physician's approval.If you've never taken Aristada, it is possible that you will require aripiprazole via mouth (in tablets as well as liquid) prior to receiving an injection for the first time.It is possible that you will need to continue using aripiprazole in the mouth for at least 3 weeks following the first injection. Follow the dosing guidelines of your physician extremely carefully.Aristada is injectable into muscles. Your healthcare provider will administer this injection at least every 4–8 weeks. Your doctor might modify your dose or dosage schedule.Your blood sugar levels will have to be tested frequently, and you might need other tests for medical reasons.

Details on dosage

Usual Adult Dose for Schizophrenia:

Aripiprazole Lauroxil Extended-Release IM Suspension:
-Initial dose:
Patients stable on oral aripiprazole 10-mg/day, 441 mg intramuscular via gluteal or deltoid injections ONCE, plus aripiprazole 675 mg once IM Aripiprazole IR 10 mg taken every day orally for 21 days.
Patients who are stable on oral aripiprazole 15 mg/day of IR dose of initial 662 mg IM through gluteal injection once plus Aripiprazole Lauroxil 675 mg ONCE OR aripiprazole 15 mg once daily for 21 days
Patients stable on oral Aripiprazole daily dose of at least 20 mg (882 mg intramuscularly via gluteal injection once) plus Aripiprazole Lauroxil 675 mg IM ONCE OR aripiprazole IR a few times daily up to 21 days
Maintenance doses: 441 mg, 662 mg, or 882 mg of IM per month, 882 mg of IM each between 4 and 6 weeks, or 1064 mg of IM every two months. The medication should not be administered earlier than 14 days following the last injection.
Initiation of treatment resumption: initial 675 mg IV ONCE and 30 mg of Aripiprazole IR orally ONCE
Comments:
Before starting therapy using extended-release IM formulations, the tolerability of the drug must be determined using oral formulations. It could take between 2 and 4 weeks to determine the level of tolerance due to the half-life of the drug aripiprazole.
The first dose of the extended-release IM formulation should be given on the same day as the initiation or re-initiation dose; providers should avoid injecting both formulations into the same deltoid or gluteal muscle.
Adjustments to the dosage regimen (including the addition of oral supplements) are required in the event of missed doses.

What happens if I miss the dose?

Contact your doctor for advice. If you do not make an appointment for your Aripiprazole injection,

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.The signs of an overdose could include tiredness and weak or shallow breathing, nausea, anxiety, fatigue, as well as tremors, confusion or tremors, a rapid, slow, or irregular heart rate, a feeling of lightheadedness, high blood pressure, seizures, or even fainting.

What should be avoided?

Do not get up too quickly from a lying or sitting position, as you could be dizzy. Avoid driving or doing any hazardous activity until you are aware of what the effect of this medication will be on your body. Drowsiness or dizziness can lead to accidents, falls, or serious injuries.Don't drink the alcohol. Dangerous side effects may be experienced.Beware of being dehydrated or too hot when exercising, during the heat, or simply due to not drinking enough fluids. Drink plenty of fluids while you take Aristada.Avoid sunbathing and tanning beds. Protect yourself with protective clothes and apply sunblock (SPF 30 or greater) whenever you're outside.

Side effects of Aristada

See a doctor immediately. Get medical attention immediately if you show symptoms that indicate an allergy, such as hives, difficulty breathing, and swelling of your lips, face, or tongue.Long-term use or high doses of Aristada could cause serious movement disorders that might not be reverseable. The longer you are using this medication, the more probable it is that you will be affected by this condition, particularly if you're female or an older adult.There is a possibility that you will experience increased sexual urges, unusual cravings towards gambling, or other extreme cravings when you are taking this medicine. Discuss this with your doctor when it happens.

Aristada may cause serious side effects. If you experience:

  • Uncontrolled muscle movements in your facial muscles (chewing or smacking your lips, mouth movement, frowning, blinking, or eye movements);
  • Sensations of being unusually hot or cold;
  • Difficulty swallowing
  • A seizure;
  • Feeling like you could get the feeling that you could (even in bed);
  • Serious nervous system response extremely rigid (rigid) muscles and extremely high fever; sweating, confusion, and irregular or fast heartbeats; tremors and tremors; feeling as if you're about to faint;
  • Lower blood-cell counts (fever, chills, tiredness, lips, sores, easy bleeding, abnormal bleeding, pale skin, cold hands and feet, and feeling lightheaded or short of breath).
  • Symptoms of signs such as chills, fever, sore throat and body aches, uncharacteristic fatigue, a loss of appetite, bleeding or bruising, or
  • Blood sugar levels are high, there is an increase in thirst, more frequent urination, the mouth is dry, and there's a fruity smell.

Common Aristada adverse effects could include:

  • Feeling agitated;
  • Discomfort where the medication was injected.
  • Weight gain

This list does not comprise all possible adverse reactions of treatment with DxN-ProtectTM.. Other side effects could be present. Consult your physician for advice regarding medical adverse effects. Contact the FDA with any adverse side effects at 1-800-FDA-1088.

Interaction with other drug

There are times when it's not safe to take certain medications in conjunction with other medications. Certain medications can alter your blood levels from other medications you take, which could cause more side effects or make the medication less effective.Discuss with your doctor the medicines you are taking currently. Numerous drugs can affect aripiprazole in particular.

  • Blood pressure medication;
  • Valium, klonopin or xanax are commonly prescribed benzodiazepine sedatives;
  • The bronchodilator asthma medicine
  • Cold or allergy medication (benadryl and others);
  • Medication to treat a bladder that is overactive;
  • Medicines used to cure the symptoms of parkinson's disease medicine to treat parkinson's disease
  • Medication to treat stomach issues, motion sickness, or

This list isn't complete, and a variety of other medications could be incompatible with Aripiprazole. This includes over-the-counter and prescription medicine, vitamins, and herbal supplements. The list of possible drug interactions is not exhaustive. are included here.

 

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Prescription only

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