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Name of Generic Origin: Trifarotene

Dosage form: Topical Cream
Drug class: Topical acne agents
Approval date: October 4, 2019
Company: Galderma
Therapy for: Acne Vulgaris

Active ingredient: Trifarotene

Inactive ingredients: Allantoin, Copolymer of acrylamide and sodium acryloyldimethyltaurate, dispersion 40% in isohexadecane, cyclomethicone, 5% ethanol, medium-chain triglycerides, phenoxyethanol, propylene glycol, purified water.

What is Aklief Cream?

Aklief Cream is an approved prescription medication that is applied to the surface (topical) in order to reduce acne vulgaris in patients who are 9 years old or older.

It isn't known whether Aklief Cream can be used safely and effectively for children who are younger than 9 years of age.

Before You Take this Drug

Before beginning treatment, inform your physician about all your medical conditions, especially those that:

  • Are skin-related issues, including sunburn, cuts, eczema, or eczema
  • You are expecting or planning to get pregnant. It isn't known whether Aklief Cream can cause harm to your baby.
  • Are breastfeeding or planning to. It is unclear whether Aklief Cream gets into breast milk. Breastfeeding mothers must apply Aklief Cream to the skin's smallest areas and for the minimum amount of time while nursing. Don't apply Aklief Cream to the area of the nipple or areola to prevent contact with your baby's.

Discuss with your doctor every medicine you are taking, such as prescription and over-the-counter supplements, vitamins, and herbal supplementation. Inform your healthcare professional that you are taking any other acne medication.

How to take Aklief cream?

  • Utilize Aklief Cream exactly as your physician instructs you to apply it. Place a light layer of cream on the affected areas every day at night.

Applying Aklief Cream:

  • Clean the area in which the cream is to be applied and dry it.
  • If you've received samples of Aklief Cream, adhere to the directions of your physician regarding the amount to apply.
  • Aklief Cream comes in a pump.
    • Press down (depress) your pump one time to disperse a tiny quantity of Aklief Cream and apply a thin layer on your face (forehead and nose, cheeks, and your chin). Beware of contact with your lips, eyes, and mouth, as well as the areas of your nose that aren't covered.
    • The pump should be pressed down two times to disperse the right amount of Aklief Cream and spread an even layer of it to the upper part of your trunk (the portion of your back in which you are able to reach, your chest, and shoulders). A second pump could be utilized to apply a light coat of Aklief Cream on the lower and middle back of your body in the event that acne is present.
  • After you start treatment with Aklief Cream, it is recommended to start applying a moisturizer to your skin regularly as necessary. Check out "Local skin irritation" below.

What should be avoided?

  • Reduce exposure to direct sunlight. Avoid tanning beds, sunlamps, and ultraviolet light while you are using Aklief Cream. If you must be in direct sunlight or are susceptible to sunlight, you should use sunscreen that has a SPF (sun protection factor) of 15 or greater and wear protective clothing as well as a wide-brimmed hat that is wide enough to cover the areas treated.
  • Avoid applying Aklief Cream to areas of the skin with abrasions, cuts, acne, or sunburned skin.
  • Do not use products for skin that may cause dryness or irritation, like:
    • Abrasive or medicated soaps and cleaners
    • Cleansers, soaps, and cosmetics that possess the ability to dry out your skin
    • products that have high levels of alcohol
  • Avoid the practice of "waxing" as a hair removal technique on skin that has been treated with Aklief Cream.

Sometimes, medicines are prescribed for reasons that are not listed in a patient information leaflet. Don't use this medication to treat a condition for which it is not recommended. Don't give it to others, regardless of whether they are suffering from similar symptoms as you are. It could harm them. It is possible to ask your physician or pharmacist for information specifically written for health professionals.

Side Effects of Aklief's

There are many possible negative side effects. For more information, talk to your physician or pharmacist. Consult your physician to seek medical advice on possible side effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088. You can also report any negative side effects to GALDERMA LABORATORIES, L.P., at 1-866-735-4137.

Aklief Cream can produce serious side effects such as:

  • Local skin reactions are typical when using Aklief Cream. They are more likely to occur within the first four weeks of treatment. They may decrease with the use of Local skin reactions are:
    • Redness
    • Scaling
    • Dryness
    • The sensation of burning or stinging

To reduce the risk of developing these local reactions, once you start treatments, it is recommended to start applying a moisturizer to your skin every time it is required. Contact your healthcare professional when you experience symptoms of a localized skin reaction.Your physician may advise you to take Aklief Cream less frequently and/or temporarily or even permanently stop the treatment. The most frequent adverse effects of Aklief Cream are sunburn and itching.

Place of Storage

  • Keep Aklief Cream at room temperature, between 68 and 75 degrees F (20 degrees between 25 and 30 degrees C).
  • Be sure to keep Aklief Cream out of direct heat.
  • If you are given an unopened trial tube of Aklief Cream via your doctor, make sure you keep the tube closed.

Make sure to keep the Aklief Cream and all medications out of reach of children.

Patient Information

Aklief Cream is to be used to treat the skin. Avoid using Aklief Cream in your eyes, mouth, or vagina.