The Web Health



Generic name: diclofenac topical [dye-kloe-fen-ak-top-ik-al]
The class of drug: topical non-steroidal anti-inflammatory drugs

What is Pennsaid?

Pennsaid is a nonsteroidal anti-inflammatory medication (NSAID). It helps by reducing the presence of certain substances within the body that cause inflammation and pain.

Pennsaid (diclofenac topical solution, 2%) can be used to relieve knee pain due to osteoarthritis.Pennsaid should only be used on the knees and is not recommended for use on any other part of the body.


Pennsaid may increase the chances of suffering a fatal stroke or heart attack, particularly if you take it over a long period of time, take high doses, or suffer from heart disease.

Pennsaid can also trigger intestinal or stomach bleeding, which can lead to fatal bleeding. These problems can develop at any time while taking this medication and are more common in older people.

Before you take this drug

Do not take Pennsaid prior to or following coronary bypass surgery (coronary bypass grafts, also known as CABG).

Diclofenac could increase the risk of a fatal heart attack or stroke, particularly if you take it for a long time, consume high doses, or suffer from heart disease. Even those who do not have heart health or risk factors can suffer a heart attack or stroke while takingIt is not recommended to use Pennsaid. If you have an allergy to diclofenac (Voltaren, Cataflam, Flector, and many others),

Don't use Pennsaid if you've ever experienced an asthma attack or a severe allergic reaction following the use of aspirin or an NSAID.To ensure that Pennsaid is appropriate for you, ask your physician if you suffer from:

  • Heart disease, high blood pressure, diabetes, high cholesterol, or if you smoke
  • An occurrence of stroke, heart attack, or blood clots;
  • A history of bleeding or stomach ulcers;
  • Asthma;
  • Kidney or liver disease,
  • Fluid retention.

Diclofenac may affect ovulation and make it harder to get pregnant if you're taking this medication.

If you are expecting and you are using Pennsaid, unless your physician tells you otherwise, Using an NSAID in the final twenty weeks of pregnancy may result in serious kidney or heart problems for the unborn baby and possibly complications in the pregnancy.

It isn't known if diclofenac can be absorbed by the milk of a nursing baby or whether it can harm the nursing infant. Do not breastfeed when taking this medication.Pennsaid is not a drug that has been endorsed for use by anyone less than 18 years of age.

Similar or related drugs

aspirin, prednisone, ibuprofen, meloxicam, naproxen, and Cymbalta

How to take Pennsaid?

Make use of Pennsaid exactly as directed by your physician. Follow the directions on the prescription label. Don't use this medication in larger quantities or for longer periods than the recommended duration. Choose the dosage that will be effective in treating your condition.

Take note of all patient information, including medication guides and instructions provided to you. Consult your physician or pharmacist for any additional concerns.Cleanse your hands following application of Pennsaid, unless treating your skin. Take at least 10 minutes before changing into gloves or dressing. You should wait at least 30 minutes before you shower or bathe.

Make sure that the skin is completely dry prior to applying any cosmetics, sunscreens, lotions, insect repellents, or any other skin care products that are medicated in the same spot you have treated with Pennsaid.

Don't apply Pennsaid to an open wound on your skin or to areas of inflammation, rash, or burn. Don't cover the area with a dressing or expose it to the heat of a hot tub or heating pad sauna.To relieve knee pain caused by osteoarthritis by using Pennsaid Apply the solution only to dry, clean skin. Apply the solution to the front, back, and sides. Make sure the solution is dry before covering the skin with clothes and applying additional skin care products such as sunscreen.

Keep Pennsaid within the room at room temperature, away from heat and moisture. Don't freeze.

What happens If I miss a dose?

Utilize the dose you missed when you remember. Do not take any missed doses if you are nearing the time for the next dose. Don't use any extra medication to replace the missed dose.

What happens if I overdose?

For medical emergencies, seek emergency attention or contact the Poison Help Line at 1-800-222-1222. There have not been any reported cases of overdoses with Pennsaid. In the event of an overdose, other similar medicines have been found to cause intestinal or stomach bleeding and high blood pressure. difficulty breathing, kidney failure, and death.

What should be avoided?

Beware of exposing your skin to the sun, heat, and tanning beds.Beware of taking Pennsaid close to your nose, eyes, or mouth. If this happens, you should rinse your mouth with water. Consult your doctor if you are suffering from eye irritation that lasts more than one hour.

Beware of drinking alcohol. It can increase the chance of stomach bleeding.Do not take aspirin or any different NSAIDs (such as celecoxib, Celebrex, Cambia, Cataflam, Voltaren, ibuprofen, Motrin, naproxen, Aleve, Anaprox, and many others) during the time you're taking this medication.

Talk to your doctor or pharmacist prior to using any cold, allergy, or other painkiller. A lot of the medicines you can buy at the pharmacy contain aspirin or other drugs similar to those found in Pennsaid. When you combine certain medicines, it can result in you taking too much of this kind of drug. Look at the label to determine whether a medication contains ketoprofen, aspirin, ibuprofen, or naproxen.

Side effects of Pennsaid

Get immediate medical attention. If you exhibit symptoms for an allergic reaction, Pennsaid: sneezing, stuffy, or runny nose; wheezing or difficulty breathing; hives; swelling of your lips, face, and tongue.

Seek medical attention immediately in the event that you exhibit symptoms of an attack on your heart or stroke. chest pain spreading into your shoulder or jaw A sudden feeling of weakness or numbness in one area of your body; speech slurred; feeling tired.

Stop taking Pennsaid and seek medical attention when you experience a severe reaction to a drug that affects various parts of your body. Symptoms may include an itch and fever, swelling of the glands, muscle aches, excessive weakness, unusual bleeding, or a yellowing of the eye or skin.

Stop taking Pennsaid and contact your doctor immediately if you suffer from:

  • An itch on the skin, however mild;
  • Breathlessness (even even);
  • Rapid weight loss or swelling
  • Symptoms of stomach bleeding: bloody or tarry stools, vomiting blood, or vomiting that appears like coffee grounds
  • Nausea, upper stomach discomfort, itching, fatigue sensation, flu-like symptoms, weight loss, dark urine, jaundice, stools that are clay-coloured (yellowing of the eyes or skin),
  • Few or no urinations, painless or difficult urine, swelling in your ankles or feet, and feeling exhausted or sluggish;
  • Extreme headache, pounding neck or ear tension, nasal bleeding, or confusion
  • Skin that is pale, lightheaded, and short of breath, rapid heart rate, difficulty concentrating,
  • The symptoms include a sore throat, fever, swelling on your tongue or face, burning eyes, and pain in the skin that is followed by the appearance of a purple or red skin rash that spreads (especially on the face or the upper part of your body) and can cause blisters and peeling.

Common pennsaid side effects can include:

  • Indigestion, gas, stomach pain, nausea, vomiting;
  • Diarrhea, constipation;
  • Headache, dizziness, or drowsiness;
  • Stuffy nose;
  • Excessive sweating and itching;
  • An increase in blood pressure
  • The pain or swelling of your legs or arms.

This is not a comprehensive list of possible side effects, and others could happen. Contact your physician for advice regarding medical effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Don't use Pennsaid alongside aspirin or any other NSAID medicines (including celecoxib, Celebrex, Cambia, Cataflam, Voltaren, ibuprofen, Motrin, naproxen, Aleve, Anaprox, and others).

Talk to your physician before taking Pennsaid in the event that you are taking an antidepressant like citalopram, fluoxetine (Prozac), fluvoxamine sertraline, paroxetine (Zoloft), trazodone, or vilazodone. If you take any of these medications along with an NSAID, it could cause bleeding or bruises easily.

Inform your doctor about all the medications you currently take and any new medications you begin or stop using, in particular:

  • Aspirin or any other NSAID pain medication (including celecoxib, Celebrex, Cambia, Cataflam, Voltaren, ibuprofen, Motrin, naproxen, Aleve, Anaprox, and others);
  • Antidepressant drugs;
  • Cyclosporine;
  • Lithium;
  • Methotrexate;
  • The blood thinner (warfarin, Coumadin, Jantoven);
  • Heart or blood pressure medications such as diuretics or "water pills";
  • Steroids are medicines (prednisone and others).

This list is not comprehensive. Other medications may interact with diclofenac, such as prescription and over-the-counter medications, vitamins, and herbal products. There are not all the interactions mentioned in this drug guide.