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Uridine triacetate

Generic name: uridine triacetate [URE-i-deen-true-AS-e-tate] Brand names: Vistogard, Xuriden
Dosage form: oral granule (triacetate, 10 g)
Drug classes: antidotes, miscellaneous metabolic agents

What is Uridine Triacetate?

This guide to medication provides details regarding the Vistogard brand of uridine triacetate. Xuriden is a different kind of uridine triacetate, which isn't covered in this medication guide.Uridine triacetate is a drug that slows down the damage to cells caused by specific cancer medications (capecitabine or fluorouracil).Uridine triacetate is a treatment for the effects of an overdose of capecitabine, or fluorouracil.

Uridine triacetate may also be employed in emergencies to treat life-threatening adverse reactions caused by capecitabine and fluorouracil. This includes the effects on the nervous system, heart, stomach, intestines, and stomach or blood cells.

Uridine triacetate is a treatment option that can be given prior to symptoms of an overdose forming. However, the treatment for uridine triacetate needs to start within 96 hours following the last time you received capecitabine or fluorouracil.Uridine triacetate can also be used for reasons not mentioned in this guideline for medication.

Side effects of Uridine triacetate

Seek medical attention immediately. Get medical attention immediately if you notice symptoms or warning signs of a reaction, such as an allergic reaction that causes hives, itching and breathing difficulties, or swelling of your lips, face, or tongue.

Common side effects of uridine can be:

  • Nausea;
  • Vomiting;
  • Diarrhea.

This list does not cover every possible side effect; others could occur. Please consult your healthcare provider regarding any medical adverse reactions and report them immediately to FDA at 1-800-FDA-1088.

Similar or related drugs



Follow the directions on your prescription label and on the label of your package. Be sure to inform your healthcare professionals about your medical issues, allergies, and all medications you take.

Before you take this drug

Before using uridine triacetate, inform your doctor about any medical conditions or allergies, as well as all medications you're taking. In some instances, it is possible that you will not be able to take the uridine triacetate drug, or you may require an adjustment in dosage or other precautions.

It isn't known if uridine triacetate could harm a newborn baby. Consult your physician if you are expecting or planning to be pregnant.It is unclear if uridine triacetate gets into breast milk or if it is harmful to the nursing infant. Inform your doctor if you are breastfeeding a child.

How to take Uridine triacetate?

Follow all the instructions on the prescription label. Don't take this medication in greater or lesser doses or for longer than the recommended time.Uridine triacetate is required every 6 hours or four times per day. It is recommended to take a total of 20 doses for a complete treatment. It will take you 5 full days to finish all the doses.

Uridine triacetate is available in an oral granule packet, which must be mixed with soft foods prior to taking. Do not consume the granules on their own.Take note of all patient information, including medication guides and instructions provided to you. Talk to your pharmacist or doctor if you have any concerns.

Adult doses are one pack (10 grams) of oral granules. A child's dose is lower than that of an adult and is determined by the child's height and weight.

To give a dose to a child, you should take less than one complete packet of oral granules. Make sure you measure your child's dosage extremely carefully to ensure that you're not giving too much or not enough medication.After weighing the child's dose After weighing the child's dose, discard the remainder of the medication in the sealed packet. Don't save it for future use.

For both children and adults Mix the dose you have measured with 3–4 ounces of soft food like pudding, applesauce, or yogurt. Take the mixture in one go, without chewing. Don't save the mixture for later use.After you have swallowed the dose of uridine triacetate, take at least 4 ounces of water.If you experience vomiting within two hours of having taken uridine triacetate, Measure the dose, mix it, and then take another dose. Then, take your next dosage at the regular time.

If necessary, uridine triacetate can be administered through the nasogastric (NG) or gastrostomy tube. Follow your doctor's directions for mixing and measuring uridine triacetate oral granules and giving the medication via feeding tubes.Take this medication for the entire prescribed amount of time, even if you are feeling good. It is crucial to finish each of the 20 doses you take to finish your treatment with uridine triacetate.

Keep unopened packages of uridine triacetate at room temperature, far from heat and moisture.Every single-use packet of uridine triacetate is designed only for use once. Discard the package after weighing your dose, even if it contains some medicine in it.

What happens if I miss the dose?

Do the dose you missed as soon as you can remember.Whenever it is close to time for another dose, do not attempt to make up any missed ones by taking extra medication in an effort to catch up with what was lost.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.A high dose of uridine triacetate is not likely to cause life-threatening symptoms.

What should be avoided?

Follow the instructions of your physician regarding any restrictions on your food, drink, or any activity.

Interaction with other drugs

Other medications can be incompatible with uridine triacetate, which includes prescription and over-the-counter medications, vitamins, and herbal products. Inform your health professionals about the medicines you are taking now and any medication that you decide to stop or modify your use of.