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Name of the Generic: Ropivacaine (also known as roe-PIV-akane [roe-PIV-a-kane]).
The Brand Names are Naropin, Naropin Polyamp, and Naropin SDV.
Drug Class: Local injectable anesthetics

What is Naropin?

Naropin can be used as an area-specific (in only one region) anesthesia for an epidural block of the spine, sometimes referred to as an epidural. It is used to give anesthesia during a surgical procedure or C-section or to alleviate pain during labor.

Naropin can also be used for reasons not mentioned in this guideline.

Side effects of Naropin

See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, like hives, trouble breathing, or swelling of your lips, face, and tongue,

Inform your caregivers immediately in the event that you are suffering from:

  • A serious blood issue known as methemoglobinemia is a severe blood problem (pale, gray, or blue-colored skin; headache or throbbing heart; shortness of breath; feeling lightheaded or fatigued;
  • Experiencing anxiety, agitation, and confusion, or as if you're about to pass out.
  • Difficulties with vision or speech;
  • Ringing in your ears, metal taste, numbness around your mouth, or shaking
  • Seizures;
  • Breath that is weak or shallow;
  • Low heart rate and weak pulse,
  • High heart rate, gasping, and feeling extremely hot.

Common adverse reactions include:

  • Feeling like you might pass out;
  • Nausea, vomiting;
  • Slow heartbeat;
  • Headache;
  • Lower back pain;
  • Fever;
  • Pain;
  • Itching;
  • Numbness, tingling, or burning pain;
  • Fatigue, pale skin fatigue, feeling lightheaded or sluggish, and cold feet and hands

It isn't a complete listing of all possible adverse consequences, but other effects may occur. Contact your physician for advice regarding medical adverse effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.


Contact your healthcare providers immediately if you experience any serious side effects like difficulty speaking, confusion or vision problems, ringing in your ears, or numbness or tingling in your mouth. You may also be gasping or experiencing strangely hot, pale, gray, or blue-colored skin, a high heart rate, headaches, breath shortness, or the feeling that you're about to pass out.

Before you take this drug

It is not recommended to use Naropin if you have an allergy to it or any other type of numbing medication.

A serious blood disorder known as methemoglobinemia can occur when you use Naropin. The risk is higher in the case of diabetes-6-phosphate dehydrogenase (G6PD) deficiency, heart issues, and lung issues. Your risk could be higher when you are taking certain medications or if the child you are with is older than six months old.

Inform your doctor if you have ever suffered from:

  • A serious blood disorder called methemoglobinemia, a serious blood disorder.
  • Kidney or liver disease,
  • Coronary heart disease.

It isn't known whether Naropin can cause harm to an unborn baby. Inform your doctor if you are expecting or planning to be pregnant.

Check with your doctor to get advice on whether it is safe to breastfeed while taking Naropin.

How to Take Naropin?

Naropin is administered by injection using a needle that is inserted into a part of your lower or middle back near your spine. This injection is administered in a surgical or hospital setting.

Your blood pressure, breathing levels, oxygen levels, and other vital indicators will be closely monitored during the time you receive Naropin.

Certain numbing medicines can cause prolonged or delayed consequences. Consult your physician if you are concerned regarding this risk. Contact your doctor when you experience joint discomfort, stiffness, or weakness in a particular part of your body following surgery or even after a few months.

What happens If I miss a dose?

Because Naropin is prescribed prior to surgery or another medical procedure, you're not likely to be following an exact schedule for dosing.

What happens If I overdose?

Contact your healthcare provider immediately. If you believe you've been exposed to too much Naropin,

What should be avoided?

Naropin may cause numbness across the entire body. Be careful not to cause injury until the sensation has gone completely.

Interaction with other drugs

Inform your doctor about all other medicines you take, including:

  • Other anesthetics—articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, and prilocaine;
  • Heart medication heart medications: nitric oxide, nitroglycerin, nitroprusside, and nitrous oxide
  • Cancer medications: cyclophosphamide, flutamide, hydroxyurea, ifosfamide, and rasburicase;
  • Antibiotics—dapsone, nitrofurantoin, sulfonamides;
  • Drugs for malaria (chloroquine, primaquine);
  • Drugs for epilepsy—phenobarbital, phenytoin, valproate;
  • Other drugs—acetaminophen, metoclopramide, quinine, and sulfasalazine.

This isn't a complete list, and other medications may influence Naropin. This includes over-the-counter and prescription drugs, vitamins, and herbal products. The interactions of all drugs are included here.