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Kedrab (human)

Name of the Generic: Rabies immune globulin (human) (test).
Names of Brands: HyperRAB, Imogam Rabies-HT, Kedrab, Bayrab Human.
Drug Class: Immunoglobulins.

What is Kedrab?

Kedrab serves to shield those who have been bitten by pets (post-exposure). Kedrab is administered in conjunction with a complete set of rabies vaccines. The medicine alone is not protection against the rabies virus. You won't need Kedrab if you've had the rabies vaccine before. Kedrab can also be used for reasons not mentioned in this guideline.

Adverse effects of Kedrab

Contact a medical professional immediately. Get medical attention immediately if you notice warning signs of an allergic response, such as symptoms of hives, difficulty breathing, or swelling of your lips, face, and tongue. Kedrab can cause severe adverse effects. Consult your physician right away. If you suffer from:

  • Fever, chills.
  • Dark urine that is dark.

Common adverse effects of Kedrab can include:

  • Headache.
  • Signs of a cold like congestion, sneezing, and a sore throat.
  • Stomach pain, gas, diarrhea.
  • Muscle pain.
  • Swelling, redness, or a lump in the area where the shot was administered.

This isn't a complete list of all the side effects. Other side effects could occur. Consult your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Kedrab is administered in conjunction with the full sequence of rabies vaccines. Kedrab is not enough to help protect against the rabies virus.

Before you take this drug

Speak to your doctor if you have ever suffered from:

  • An allergic reaction to an immunoglobulin protein.
  • An immunoglobulin A (IgA) deficiency.
  • Heart-related problems.
  • Coronary arterial condition (clogging the arteries).
  • A stroke or blood clot.
  • A blood cell or blood-clotting disorder.
  • High triglycerides (a kind of blood fat).
  • An "in-dwelling" catheter.
  • If you've had or have been ridden.

If you are nursing or pregnant, see your doctor. Kedrab is derived from human plasma donated by donors and could contain viruses and different infectious agents. Donated plasma is analyzed and processed to lower the risk of contamination; however, there's a possibility of it transmitting the disease. Discuss with your physician about the potential danger.

How to take Kedrab?

Kedrab is injected directly into muscles directly into or near the area of injury (animal scratch or bite) that exposes you to the virus rabies. The healthcare provider will provide the injection. The dose of Kedrab is administered when you get the first of your rabies vaccine doses or within 7 days following the vaccination. You must take all doses that are recommended for the rabies vaccine; otherwise, you could not be completely protected from the disease.

What happens if I miss a dose?

Kedrab can be used in one dose and doesn't have a day-to-day dosing schedule

What happens if I overdose?

Because Kedrab is prescribed by a health expert in a medical environment, it is highly unlikely for an overdose to occur.

What should be avoided?

Don't receive any "live" vaccine while using Kedrab for at least three months following the use. The vaccine may not function in the same way and might not be able to fully protect you against diseases. Live vaccines comprise measles, mumps, and rubella (MMR), as well as the typhoid virus, polio, rotavirus varicella, yellow fever (chickenpox), and zoster (shingles). You must wait at least 4 months after receiving the Kedrab vaccine before you can get the measles vaccination.

Interaction with other drugs

Inform your doctor about the other medicines you are taking, particularly birth control medications as well as hormone replacement therapy. Other medications can affect Kedrab, which includes medications that are prescribed and available over the counter, vitamins, and herbal products. Discuss with your doctor all the medicines you are currently taking as well as any medications you are about to start or stop taking.