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Pronunciation: am -jeh-vee’-tah
Generic name: adalimumab-atto
Dosage form: Amjevita SureClick Auto-injector (40 mg/0.8 mL), Amjevita Prefilled Syringe Injection (40 mg/0.8 mL, 20 mg/0.4 mL, 10 mg/0.2 mL)
Drug classes: antirheumatics, TNF-alpha inhibitors

What is Amjevita?

Amjevita (adalimumab-atto) is an endocrine biosimilar of Humira, which is an TNF-alphaIt blocker. which is used to treat inflammation, pain, and skin manifestations when autoimmune diseases are present. Amjevita is prescribed for treating rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis (AS), Crohn's disease, ulcerative colitis, plaque-psoriasis, as well as hidradenitis suppurativa and uveitis.Amjevita is a biosimilar of Humira. Biosimilars are drugs that are similar to Humira's original product but manufactured by a different company. Amjevita is not an interchangeable biosimilar. Amjevita can be purchased as an autoinjector or an already-filled syringe.


Amjevita impacts the immune system. It is possible to contract infections more frequently, and even deadly or serious infections.Prior to or during treatment with your physician, inform him when you show indications of infections like fever, fatigue, chills, pains, cough, skin sores, diarrhoea, or burning after you go to the bathroom.The doctor will test you for etuberculosis (TB) prior to beginning treatment with Amjevita and monitor you closely for signs and symptoms of TB while you are taking treatment.The risk of developing cancer is higher in adults and children who take TNF-blockers.

Prior to use this drug

Before you begin using Amjevita, consult your doctor if you're experiencing symptoms of infection such as fever, chills, sweats, fatigue, muscle pain, and cough. Also, you may experience bloody mucus, skin rashes, burning pain whenever you go to the bathroom, or feeling tired constantly.Amjevita is only recommended within the age group for particular conditions. Amjevita is approved by the FDA for treating Children who are using Amjevita must be current on all vaccines for children prior to starting treatment.

Inform your doctor if you were ever diagnosed with:

  • Tuberculosis (or the case that someone in your family is suffering from tuberculosis);
  • An ongoing infection;
  • Cancer;
  • Hepatitis b (amjevita could cause the hepatitis b virus in the future to return or become worse);
  • Diabetes;
  • Heart failure;
  • Any sensation of numbness or the sensation of tingling, or a neuromuscle disorder like the condition known as multiple sclerosis and guillain-barre syndrome;
  • If you're scheduled for a significant surgery or
  • If you've recently had or are planning to get any vaccinations,

Inform your physician about the location you reside in and if you have recently travelled or are planning to travel. There is a chance that you could be exposed to illnesses that are common in specific regions of the world.Amjevita can cause a rare form of lymphoma (cancer) of the spleen, liver, and bone marrow, which could be fatal. It is most common among young people and teens suffering from Crohn's disease and ulcerative colitis. However, people who suffer from an autoimmune condition that causes inflammation could have a greater chance of developing lymphoma. Consult your doctor about the risk you face.


It isn't known if Amjevita could cause harm to an unborn baby. Discuss with your doctor if you are expecting or planning an unplanned pregnancy. Check with any doctor caring for your baby's health who is aware of the fact that you took Amjevita during your pregnancy, especially prior to the baby's vaccinations.


It is not always safe to breastfeed your baby while taking Amjevita. Talk to your doctor about your concerns and the safest way to feed your baby using Amjevita.Amjevita pregnancy and breastfeeding information (more details)

How to take Amjevita?

Make sure you use Amjevita exactly as directed by your physician. Follow the instructions on the prescription label and review all medication guides or instructions sheets. Use the medication exactly according to your doctor's instructions.Amjevita is injected underneath the surface of the skin (subcutaneous injection) by using an autoinjector or a syringe that has been prefilled.The dosage schedule for Amjevita is based on the severity of the condition you're treating. Follow the dosing guidelines of your doctor extremely carefully.A medical professional will show you how to use Amjevita independently. Don't use Amjevita when you do not know the guidelines for using it correctly. Ask your doctor or pharmacist if there are any questions.Don't take this medication. If you show any signs of infection, Consult your physician for advice.You should prepare your injection when you are ready to administer it. Avoid using it if your medicine appears cloudy, changes colour, or has particles. Contact your pharmacist to request a new medication.Place the auto-injector or prefilled syringe at room temperature between 68°F and 77°F (20°C to 25°C) for 15–30 minutes so that it can warm up. Do not heat the prefilled syringe with heating sources like boiling hot water or in a microwave.

Pick a site for injection. It is possible to inject the thighs' front or your abdomen, excluding the two inches (5 centimetres) around your stomach button (navel). Make sure to rotate the injection site every time you administer an injection. Every new injection site must be at least 1.2 millimetres (3 cm) from the injection site that you previously used.Do not inject into the skin that is red, fragile, brittle, broken, bruised, or scarred. Do not inject into your clothing.Amjevita can affect your immune system, which means you are more susceptible to getting infections, and even more severe or fatal infections. Your physician will have to check on you regularly.Use a needle or syringe just once, and then place them into the puncture-proof "sharps" container. Be sure to follow the laws of your state or city regarding how to dispose of the container. Be sure to keep it safe from your reach for children and pets.

Details on dosage

The dosage and frequency of Amjevita depend on severity, age, and the condition being treated. For more details on specific dosage schedules, follow the hyperlink below.

Amjevita is available under the following names:

  • Amjevita sureclick Autoinjector 80 mg/0.8 ml, 40 mg/0.8 ml, 40 mg/0.4 ml
  • Amjevita Prefilled Syringe, 80 mg/0.8 millilitres, 40 mg/0.8 ML, 40 mg/0.4 ML 20 mg/0.4 millilitres; 20 mg/0.2 ML; 10 mg/0.2 millilitres.

For more information about dosage, follow the link below.

What happens if I miss the dose?

Take the medication when you remember, and then you can resume your regular dosage schedule. Do not take additional medicine to compensate for the missed dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

What should be avoided?

Don't inject into the skin that has been damaged, is red, tender, or hard.Avoid being around those who are ill or suffer from infections. Contact your doctor right away when you begin to show symptoms of an infection.Do not get a "live" vaccine while using Amjevita. The vaccine might not function in the same way during this period and could not completely protect you from diseases. Live vaccines comprise measles and mumps rubella (MMR), typhoid, polio, and rotavirus varicella, yellow fever (chickenpox), or the zoster (shingles).

Side effects of Amjevita

Contact a medical professional immediately. If you experience any of these symptoms that indicate an allergy reaction, Amjevita: hives, breathing difficulties, or swelling of your lips, face, tongue, throat, or face

Make contact with your physician as quickly as you can.If you notice any signs of lymphoma,

  • Fever, swollen glands, night sweats, and a general feeling of illness;
  • Joints and muscle discomfort, skin rash, and easy bruising bleeding;
  • Pale skin and feeling lightheaded or short of breath; frigid hands and feet
  • The pain in your stomach, which may then extend to your shoulder or
  • Insomnia, feeling fuller after eating one or two bites, weight loss

Make sure to contact your doctor at any time if you suffer from:

  • Either new or worsening worsening or new (raised and white flaking on the face);
  • An abrasion or a bump in your face that doesn't heal;
  • Signs of sepsis include chills, confusion, fatigue, fast heartbeats, quick breathing, and a feeling of being sick.
  • Liver problems—bodyaches and fatigue stomach pain, right-sided stomach pains, vomiting, hunger loss, dark urine, black stool, and jaundice (yellowing of the eyes or skin);
  • Lupus-like condition: joint discomfort or swelling in the chest and shortness of breath. The skin's colour changes in the sun.
  • Nerve disorders: numbness, sensation of tingling, dizziness, vision problems, or weakness in your legs or arms
  • The signs of tuberculosis include a chronic cough and fever and the loss of weight (fat or muscular).

Adults who are older are more likely to get cancer or infections when using Amjevita.

Common adverse effects of Amjevita can include:

  • Headache;
  • Symptoms of the cold, like sinus pain, a stuffy nose, and sneezing. Sore throat;
  • The rash
  • Redness, swelling, itching, or swelling at the site of the injection.

This isn't a complete list of possible side effects, and others could happen. Consult your physician to seek medical advice on the effects. It is possible to report any symptoms to the fda by calling 1-800-fda-1088.

Interaction with other drugs

Certain medications should not be taken with amjevita. Discuss with your doctor any medications you are taking and also the medicines you are about to start or stop taking when you're taking amjevita, particularly:

  • Abatacept, etanercept;
  • Anakinra;
  • Azathioprine, 6-mercaptopurine, or
  • Certolizumab, golimumab, infliximab, and rituximab.

Do not use live vaccines.This list isn't comprehensive. Other drugs can be incompatible with Amjevita, which includes prescription and over-the-counter medications, vitamins, and natural products. There are many possible interactions that are not mentioned.




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