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Xtampza ER

Generical name: oxycodone
Dosage format: extended-release capsules
Drug class: opiates (narcotic analgesics)

What is Xtampza ER?

Xtampza ER is:

  • A powerful prescription pain medication that contains an opioid (narcotic) that is employed to treat pain that is severe enough to warrant continuous, 24/7 long-term treatment using an opioid if other options for treating pain, such as non-opioid pain medication or immediate-release opioid medications, don't adequately treat your pain or do not work for you.
  • Long-acting (extended-release) drug for pain medication that could expose you to overdose and even death. Even if you're taking your medication according to the dosage prescribed by your doctor, you're at risk of addiction to opioids through misuse, abuse, and addiction, which can cause death.
  • It is not recommended to treat discomfort that isn't continuous.


  • Seek emergency assistance immediately in the event that you are taking excessive amounts of Xtampza (an overdose). When you begin taking Xtampza in an emergency room, the dose you take is altered, or if you consume excessive amounts (overdose), you may experience severe breathing issues that could result in death.
  • The use of Xtampza In combination with other opioid medications, alcohol, benzodiazepines, or any other central nervous system stimulants (including street drugs) can result in severe somnolence, reduced awareness, breathing issues, or coma. Death can also occur.
  • Don't offer anyone else your Xtampza error. You could be killed by it. The act of selling or giving away Xtampza ER is against the law.
  • Securely store this medication away from children and in a place that is not accessible to anyone else, not even guests.

What happens if I miss a dose?

Do not consume Xtampza ER if you have:

  • Difficult breathing or any other lung issues.
  • Bowel obstruction, or a narrowing of the stomach or the intestines.

Similar/related drugs

aspirin, acetaminophen, tramadol, duloxetine, naproxen, oxycodone, and tylenol

Then take Xtampza ER.

Before you take Xtampza ER, tell your physician if you've had any of the following:

  • Head injury, seizures
  • Problems with urination
  • Thyroid, kidneys, and liver problems with thyroid, liver, and kidneys
  • Gallbladder or pancreas problems
  • Addiction to prescription or street alcohol, drugs, or mental health issues.

Inform your doctor if you:

  • Expecting or expecting to be pregnant or planning to be pregnant. Prolonged use of xtampza er during pregnancy could trigger withdrawal symptoms in the newborn baby. These symptoms could pose a risk to your baby if they are not treated and recognised.
  • Not recommended during treatment. It can cause harm to your baby.
  • Taking prescription or over-the-counter medicines such as vitamins and herbal supplements. The combination of xtampza with other medications can result in serious side effects that could cause death.

How to take Xtampza ER

  • Do not change your dose. Make sure you take this medicine exactly in accordance with the advice of your doctor. Take the lowest dosage possible to get the most effective result.
  • The dose you are prescribed is taken every 12 hours and all at once each day. Do not exceed the dose prescribed. If you are unable to take a dose, you can take the next dose at your regular time.
  • If you're unable to take the capsules, refer to the complete instructions for use.
  • Take the capsules at the same time with a similar amount of food to make sure that the medicine is fully absorbed.
  • Take the capsule in its entirety. Don't snort or inhale Xtampza ER, as this can result in an overdose and even death.
  • The capsules' contents could be sprinkled over soft food items, then sprinkled into a glass and directly into your mouth. Or, it can be administered via a nasogastric or gastrostomy tube.
  • Consult your physician to let them know that the medication you're taking isn't enough to control the pain.
  • Do not discontinue your Xtampza ER without speaking to your healthcare professional.
  • Get rid of expired, unneeded, or unneeded Xtampza by flushing them down the toilet, in case an option for taking back the drug is not accessible. Visit for additional information on the disposal of unused medicines.

What should be avoided?

  • Operate or drive heavy equipment until you are aware of how Xtampza ER can affect you. Xtampza ER could make you feel dizzy, sleepy, or lightheaded.
  • Consume alcohol, or use prescription-only or other medications with alcohol. Drinking alcohol-containing medications when you are taking Xtampza ER could result in an overdose and leave you dead.

Side effects of Xtampza ER

Possible side effects can include:

  • Nausea, constipation and tiredness. Dizziness, headache as well as abdominal painfulness. Consult your physician in the event that you experience all of these signs and they are serious.

Take immediate medical care for:

  • Difficulty breathing, shortness of breath, rapid heartbeat, chest discomfort, swelling of your tongue, face, or throat, severe fatigue, lightheadedness while shifting positions, experiencing faintness or agitation, excessive body temperature, difficulty moving, tight muscles, or mental changes like confusion.

There are many possible adverse consequences. Contact your doctor to get medical advice on possible side effects. If you have any concerns, report the reaction to FDA by calling 1-800-FDA-1088.




Prescription only

Pregnancy & Lactation

CSA Schedule*

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