What is Paliperidone?
Paliperidone is a medication used by the adult population to help treat schizophrenia. The drug is also used in combination with other medications to treat schizoaffective disorder in adults.
Paliperidone is also used for reasons not mentioned in this guideline for medication.
Side effects of Paliperidone
Contact a medical professional immediately. If you are experiencing warning signs of an allergic response, such as symptoms of hives, difficulty breathing, and swelling of your lips, face, and tongue,
Inform your doctor right now if you show any of these symptoms of a serious disorder of movement:
- You may feel tremors or shakes in your legs or arms.
- Muscles that are not controlled within your facial muscles (chewing, lip smacking, frowning, tongue movements, blinking, or eye movements)
- Any unusual or new muscles you are unable to use.
Paliperidone may cause serious side effects. Consult your physician immediately if you experience:
- Lower blood pressure rapid or pounding heartbeats, a flutter within your chest, rapid breathing, and sudden dizziness (like you're going to faint);
- Difficulties in being unable to think or feel steady;
- Trouble swallowing
- Seizure;
- Breast swelling and tenderness; tenderness of the breasts;
- Excessive cholesterol and weight gain
- Fever, chills, irritation of the throat, mouth sores, feeling lightheaded;
- Abnormal blood cell count;
- Blood sugar levels are high—increased thirst, a higher frequency of urination, a dry mouth, and a fruity breath smell;
- Extreme nervous system reaction: very rigid (rigid) muscles with high fever, sweating or trembling, rapid or irregular heartbeats, or the sensation that you may be stricken with a stroke;
- Impotence or erectile that is uncomfortable or lasts for more than 4 hours;
- Menstrual changes can be seen during your period.
Common negative side effects of paliperidone include:
- Headache, dizziness, or drowsiness;
- Symptoms of a cold like nasal stuffiness, sneezing, a sore throat,
- Being anxious or restless;
- Muscle stiffness, tremors, or shaking;
- Muscles that aren't controlled; issues with walking or speech;
- Issues with balance or eye movement
- Weight gain
- Upset stomach, constipation;
- Rapid heart rate
- Swelling, pain, bruises, or irritation in the area at the site of injection.
This isn't a complete list of possible side effects, and other side effects could occur. Consult your physician to seek medical advice on adverse effects. You can report any symptoms to the FDA at 1-800-FDA-1088.
Similar or related drugs
Abilify Maintena, Caplyta, Fluoxemic, Quetiapine, Abilify, Seroquel, and Aripiprazole
Warnings
Paliperidone has not been recommended for use in older adults suffering from dementia-related psychosis.
Before you take this drug
It is not recommended to use paliperidone in the event that you are allergic to paliperidone or the chemical risperidone (Risperdal).Paliperidone can cause an increase in the likelihood of dying in elderly patients suffering from psychosis related to dementia. It is not permitted for use in this manner.
Long-term or high-dose use of paliperidone could cause serious movement disorders that might not be reversible. The longer you are using paliperidone, the more likely you will be affected, particularly in the case of women or older people.
Prior to receiving your first injection, inform your doctor if you've not previously taken oral paliperidone or risperidone.
Inform your doctor if you were ever diagnosed with:
- Heart conditions, heart disease, or heart attack;
- The long QT disorder (in the case of you or a member of your family);
- Blood pressure, low or high, as well as fainting symptoms;
- Low white blood cell (WBC) count;
- A serious neurological disorder that can result from taking an antipsychotic drug;
- Muscles that are not controlled in your facial muscles (chewing lip smacking, chewing mouth movement, frowning blinking, or eye movements);
- Seizures or epilepsy;
- An electrolyte imbalance (such as blood levels that are low in magnesium or potassium);
- Diabetes (in the case of you or an immediate relative);
- Tumor in the breast
- Kidney or liver disease
It is unclear whether paliperidone harms an unborn child. Talk to your doctor if you are expecting to be pregnant.The use of antipsychotic medication within the last 3 months of pregnancy could create serious health issues in the infant. Tell your doctor right away if you get pregnant.
If you're expecting, then your name might be included on an ob-gyn registry to monitor the effect of paliperidone on the infant.Consult your doctor to determine whether it is safe to breastfeed while taking this medication.
How to take Paliperidone?
Paliperidone is injectable into muscles. A doctor will administer the injection.The Invega Sustenna is generally given once per month; however, the first two doses are administered at the same time but one week apart.
Invega Trinza is typically given every 3 months after you've been using Invega Sustenna for at least 4 months in a row.Invega Hafeera is typically given every six months after you've utilized Invega Sustenna for at least four months or Invega Trinza for at least one cycle.
Stay under the supervision of a doctor when using paliperidone. Take paliperidone on a regular basis to get the most effective outcomes.Your doctor should examine your health regularly.
What happens If I miss a dose?
Consult your physician for the appropriate treatment in the event that you don't make the appointment for the injection of paliperidone.
What happens if I overdose?
For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.
Overdose symptoms can include drowsiness, an unsteady feeling, pounding or rapid heartbeats, and feeling as if you could pass out.
What should be avoided?
Beware of drinking alcohol. Dangerous side effects can be experienced.Beware of becoming dehydrated or overheated when exercising in hot weather or simply by not drinking enough fluids. Follow the advice of your physician about the amount and type of fluids you must drink.
Avoid driving or engaging in hazardous activities until you understand how paliperidone affects you. Drowsiness, dizziness, or confusion can cause accidents, falls, or even severe injuries.Do not get up too quickly from a lying or sitting position, as you could get dizzy.
Interaction with other drugs
There are times when it's not recommended to take certain medications in conjunction with other medications. Certain drugs may affect the blood levels and the other drugs that you are taking, which can cause more side effects or make the medications less effective.
A variety of medications can impact paliperidone. This includes over-the-counter and prescription medications, vitamins, and herbal products. Not all interactions are mentioned here. Inform your doctor about any other medications you take.
