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Do Antibiotics Make You Tired And Feel Sick?

Have you started feeling more tired and sleepy and wondered if it may be due to the antibiotics you are taking? Or the doctor has prescribed you antibiotics, and you are worried about their potential concerns? Fred, we have the answers to all your questions. 

Yes, Antibiotics can make you feel tired. There are several side effects of antibiotics, and fatigue or tiredness is one of them. Remember, your fatigue or tiredness doesn’t need to be due to antibiotics if you take them; it may also be due to several other factors. 

After going through this detailed blog post, you will know about Antibiotics and their relation with tiredness. We have also shared ways to get rid of this side effect below. Keep reading as we start uncovering more about this topic.   

Type Of Antibiotics That Can Cause Tiredness

Antibiotics are medicines used to treat bacterial infections. Different types of antibiotics are used to treat various diseases. Here is a 2020 research that proved antibiotics can cause tiredness in some people. Here are some of the most common antibiotics which may cause fatigue. 

  • Amoxil, Moxatag (amoxicillin)
  • Z-Pak, Zithromax, Zmax (azithromycin)
  • Cipro, Proquin (ciprofloxacin)

These are some of them which may cause fatigue. The best way to deal with it is to consult a doctor before taking these medicines. If you are taking them and facing fatigue due to them, read the section below to get rid of them. 

How To Get Rid Of It?

The best way to eliminate tiredness due to Antibiotics is to talk to your doctor. He will first examine the causes and then take the necessary actions. It may be changing your dosage, timing, or the type of Antibiotics.

Usually, these are taken in sensitive conditions when their use is necessary, and their use is not stopped due to mild side effects. So, if you need to complete your course and taking antibiotics is a must, here are some ways to combat tiredness alongside its usage.  

Ways To Combat Tiredness By Antibiotics

These are the practical tips to reduce fatigue caused by Antibiotics. Practicing these techniques will make you feel better. 

  • Quality Sleep: The first practical method is getting quality sleep. Get a good 7 to 8 hours of sleep at night. It is necessary for the body to recover and will keep you active and fresh during the day.
  • Take a Healthy diet: Taking a healthy diet is the next tip to combat tiredness due to Antibiotics on our list. Take a diet rich in nutrients. Increase fruits, vegetables, whole grains, and avoid processed sugar and high-fat foods. It will also help you to keep energetic.  
  • Taking probiotics: Taking probiotics increases your gut bacteria. It can also help you avoid fatigue. Yogurt, tempeh, miso soup, sauerkraut, cottage cheese, and buttermilk are some examples of rich probiotic foods.   
  • Exercise regularly: Regular exercise can also help in increasing your energy levels. If you can’t exercise, you can even start by just walking. It will boost your mood and strengthen your body to fight weakness and tiredness. 
  • Drink plenty of water; Staying hydrated is very necessary. Dehydration can cause fatigue, exhaustion, and weakness. Ensure you are drinking plenty of water to stay hydrated during the day.  
  • Prevent alcohol and other drugs: Using alcohol and other recreational drugs can also affect your sleep. It can lead to increased tiredness during the day, so preventing them will also be an aid in getting rid of this. 

Other Potential Reasons For Tiredness

There can be several reasons for feeling tired or sleepy while taking Antibiotics. Carefully diagnose whether it is due to Antibiotics or other factors and then take the necessary actions.  

Chronic Conditions or Infection

The first and the most probable cause of tiredness, except for Antibiotics, can be underlying infection. It can be due to the ongoing illness you are suffering from, not the medications. Other chronic conditions like heart problems or diabetes may also be the reason for this tiredness.  


The duration and the quality of your sleep are also significant in this regard. Your body cannot recover fully if you are not getting enough sleep or it’s not a good quality sleep. It can also cause tiredness during the day and make you feel sleepy.   


Your medications can also be the reason for your tiredness. Here are some of the medications that can cause fatigue, except Antibiotics. 

  • Antidepressants
  • Anxiety tablets
  • BP medications
  • Radiation therapy
  • Chemotherapy
  • Cough medications
  • Pain medicines
  • Heart medicines
  • Antihistamines

Other Side Effects Of Antibiotics Except Tiredness 

Antibiotics may also have potential side effects, such as tiredness. Here are a few of them;

  • Digestive Issues: Digestive issues are one of the common problems associated with Antibiotics. These problems may include vomiting, nausea, diarrhea, and indigestion.   
  • Yeast Infections: Another side effect of these medicines is yeast infections. The symptoms of these infections include white discharge, itching, and rashes. 
  • Skin Problems: You may also face skin problems because of Antibiotics. These may include skin reactions and can cause rashes, hives, itches, and can even cause shortness of breath. 
  • Photosensitivity: Another side effect of Antibiotics is photosensitivity. It means sensitivity to sunlight. It is a reaction which is caused by our immune system.  

Final Words

Hopefully, you have got the answer. Do antibiotics make you tired? Wrapping it up may be a side effect of Antibiotics, but it can also be due to several other factors. The best way to use Antibiotics is to use them according to your doctor’s prescription. It will protect you from tiredness, fatigue, and all other potential concerns.

If you have any problems due to these medications, contact your doctor and update him about your situation. If it’s a mild side effect, continue with your prescription unless your doctor tells you. Practising the techniques to combat tiredness will help you safely use Antibiotics.    


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