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Genric Name: Quinapril KWIN-april ] 

Drug Class: Angiotensin Reconverting enzymes inhibitors

What is Accupril?

Accupril (quinapril) is a medication used in adults either on its own or with other medicines to manage the problem of high blood pressure (hypertension). The reduction in blood pressure could reduce your chance of suffering a stroke or heart attack.

Accupril can also be used by adults along with other medicines to treat heart failure.

It reduces certain chemicals that tighten blood vessels, ensuring that blood flows more easily and the heart can pump blood more efficiently.


Don't use Accupril if you are expecting it. If you are pregnant discontinue taking this medication and notify your doctor immediately.

Do not take Accupril if you've ever suffered from angioedema. Don't use Accupril for more than 36 hours before or after taking medication that contains sacubitril(such as Entresto).

If you suffer from diabetes take care not to take Accupril along with any medicine that contains Aliskiren. an anti-blood pressure medication (brand brands comprise Tekturna or Tekamlo).

Before You Take This Drug

Before you start taking this medicine, make sure to consult your doctor.

You shouldn't take Accupril if you are allergic to quinapril or:

You are allergic to other ACE inhibitors, like benazepril and captopril. Also, you are allergic to en fosinopril, lisinopril moexipril and perindopril or trandolapril.

Do not consume Accupril within the first 36 hours of or after taking a medicine that has sacubitril (such as Entresto).

If you are diabetic take care not to take Accupril in conjunction with any other medicine that contains an ingredient called Aliskiren (a blood pressure medication).

It is also possible to stay clear of taking Accupril with the aliskiren if you suffer from kidney problems.

To be sure Accupril is suitable for you, inform your physician if you've ever experienced:

  • Heart issues;

  • Low blood pressure;

  • The potassium levels in the blood are high ( hyperkalemia);

  • Low white blood cell count;

  • Diabetes;

  • kidney diseases (or if you're taking dialysis) or

  • Liver disease.

Don't use Accupril if you are expecting it. Stop taking the medication and notify your doctor immediately if you find yourself pregnant. Quinapril could cause harm or even death to an unborn baby if you use Accupril in the third or second trimester.

How to Take Accupril?

Use Accupril exactly as directed by your physician. Follow the instructions on the prescription label and study all instructions or medication guides. The doctor might alter your dosage.

Your blood pressure needs to be monitored regularly. The function of your liver or kidneys might also require to be examined. Contact your doctor if are experiencing persistent diarrhea or diarrhea or if you have more sweating than usual. You could easily get dehydrated when you take Accupril. This could lead to lower blood pressure and electrolyte imbalances or kidney failure.

Inform your doctor if you are planning a procedure.

If you suffer from elevated blood pressure continue taking Accupril even if you're feeling good. High blood pressure can have no signs.

Detail On Dosage 

Usual Adult Dose for Hypertension:

Initial dosage: 10 to 20 mg orally, once a day in patients who aren't on diuretics.

Maintenance dosage: 20 to 80 mg per day orally taken as one dosing or two doses equally divided

Usual Adult Dose for Congestive Heart Failure


Initial dose: 5 mg taken orally twice daily

The dosage for maintenance is 20 to 40 mg per day orally in two doses equally divided

This dose can help alleviate the symptoms associated with heart disease however, increases in the exercise duration typically require more doses.

If the initial dose is tolerated well the patient should be adjusted at intervals of weekly intervals until they have reached an effective dose.

Management of heart failure as an adjunct to conventional treatment, including diuretics or digitalis

Usual Geriatric Dose for Congestive Heart Failure:

10 mg taken orally, once a day

Treatment of hypertension

Management of heart failure an adjunctive therapy, when it is combined with traditional therapy, such as diuretics or digitalis

Usual Geriatric Dose for Hypertension:

10 mg orally every day


Treatment of hypertension Management of heart failure as an adjunct to traditional therapy, such as diuretics or digitalis

What Happens If I Miss a Dose?

Do not take the medicine for as long as you can. However, avoid any missed doses if it's close to the time of the next dose. Don't have two doses at one time.

What Happens If I Overdose?

Get medical attention in an emergency or contact for help at the Poison Help line at 1-800-222-1222.

What Should be Avoided?

Don't consume potassium supplements or salt substitutes, unless your doctor has instructed you to. Do not get up too quickly from a lying or seated place, as you could be dizzy.Beware of becoming dehydrated or overheated when exercising, in the heat, or by insufficient fluid intake. Follow the advice of your physician about the kind and quantity of liquids you must consume. In certain instances drinking too much fluid could be as harmful as drinking too little..

Accupril side effects

Adverse Side Effects

See a doctor immediately If you show symptoms that you are experiencing an allergic reaction Accupril: hives or breathing problems and swelling of your lips, face, and tongue. Accupril may cause serious side effects. 


  • Chest or chest pain that is fast or slow heart rate;

  • A feeling of lightheadedness that makes you feel like you're about to pass out.

  • Heart-related problems swelling rapidly gaining weight Feeling short of breath, and swelling;

  • Kidney issues - increased urination and feeling tired or exhausted;

  • Liver issues nausea stomach discomfort (upper right side) Itching, fatigue dark urine, stool Colored by clay, jaundice (yellowing of the eyes or skin), and other irregular liver tests

Mild Effects

symptoms of signs of infection fever colds sore throat or body aches, fatigue, loss of appetite bleeding or bruising, or hypertension of blood potassium - nausea weak and tingly sensations chest pain, irregular heartbeats lack of movement.

  • Headache

  • Nausea, vomiting, stomach pain;

  • Cough 

  • Dizziness, tiredness.

This is not a comprehensive list of possible side effects, and other effects may also be present. Contact your physician to get medical advice on adverse effects.

Interaction with Other Drugs

Discuss with your doctor all other medications including:lithium;

  • A diuretic, or "water pill";

  • Gold injections for arthritis;

  • Temsirolimus, sirolimus, or everolimus; or

The NSAIDs (nonsteroidal anti-inflammatory medicines) Aspirin, Ibuprofen (Advil, Motrin), naproxen (Aleve) Celecoxib, diclofenac, indomethacin and meloxicam, and others.

This list isn't complete. Other medications can interact with quinapril. There are many possible interactions between drugs. are listed here.