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The Xpovio 80 mg tablet is taken twice a week.

Name of the generic: selinexor [SEL-iNEX-
Brand names: Xpovio 100 mg once-weekly; Xpovio 40 mg once-weekly; Xpovio 40 mg twice-weekly; Xpovio 60 mg once-weekly; Xpovio 60 mg twice-weekly; Xpovio 80 mg once-weekly; Xpovio 80 mg twice-weekly.
Classification of drugs: miscellaneous antineoplastics

What is Xpovio, 80 mg twice a week?

Xpovio 80 mg twice weekly is taken with bortezomib or dexamethasone to treat multiple myeloma in adults.The Xpovio dosage of 80 mg twice weekly is also taken by people over the age of 18 to control certain kinds of lymphoma that are diffuse and large.

The Xpovio dosage of 80 mg twice weekly is administered after other drugs have failed or been discontinued.Xpovio 80 mg twice a week has been approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, certain patients have responded to Xpovio 80 mg twice weekly; however, further research is required.The Xpovio dosage of 80 mg twice weekly can also be prescribed for other purposes that are not covered in this guide.

Side effects of Xpovio 80 mg

Contact a medical professional immediately. If you are experiencing warning signs of an allergic response, such as symptoms of hives, difficulty breathing, and swelling of your lips, face, and tongue,The Xpovio dosage of 80 mg twice weekly can trigger serious or fatal adverse effects. Some adverse reactions may not manifest until after you've taken this medication for a few days or weeks.

Xpovio 80 mg twice a week can result in serious adverse reactions. Contact your physician immediately if you experience:

  • Blurred vision blurred vision, pain in the eyes, or seeing halos of light sources;
  • Severe ongoing nausea, vomiting, or diarrhoea;
  • Loss of appetite, which stops you from eating and can cause weight loss;
  • Confusion or dizziness, fainting, and changes in mental state;
  • Signs, warning signs sepsis signs of sepsis the symptoms of sepsis include fever and chills. Intense fatigue, rapid heartbeats, quick breathing, and feeling extremely sick;
  • Symptoms of signs of fever symptoms of infection such as chills signs of infection include chills, fever manifestations, a cough with mucus, throat and mouth ulcers, feeling breathless and tingling, or a painful blistering skin rash on the other or both sides of your body.
  • Low sodium level low sodium levels, headaches, and slurred speech. Extreme weakness, vomiting, and loss of coordination. Feeling unstable.

The treatment you receive could be delayed or removed if you suffer from specific adverse consequences.

Common adverse effects of Xpovio mg twice a week could include:

  • Dual vision and blurred vision sensitive to light or glare
  • Tiredness;
  • Numbness, tingling, as well as burning or numbness in your feet or hands;
  • Anaemia, bleeding, bruising, or bleeding
  • Higher blood sugar levels
  • Infection, fever, cold, or flu symptoms;
  • Shifts in mineral and sodium levels;
  • Irregular kidney or liver function tests;
  • Nausea and vomiting, as well as nausea, vomiting,
  • Diarrhoea, constipation;
  • Weight loss;

This is not a comprehensive list of possible side effects, and other side effects could occur. Contact your doctor for advice regarding medical adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.


It is possible to contract infections more frequently, even severe or fatal infections. Call your doctor when you experience fever, chills, flu-like symptoms, chills such as cough, mouth ulcers, or trouble breathing.Xpovio, 80 mg twice weekly, could also lead to lower blood platelet counts. Contact your physician immediately in the event of unusual bruising or bleeding.

Before you take this drug

Speak to your doctor if you are ever diagnosed with:

  • Cataracts;
  • Bleeding issues as well as
  • An active or recent infection.

There is a chance that you'll have to undergo an unfavorable pregnancy test prior to beginning this procedure.Women and men taking Xpovio 80 mg twice weekly should take effective birth control to avoid the birth of a baby. Xpovio 80 mg twice weekly could harm a baby born when the father or mother is taking this medication.Use contraceptives for a minimum of one week after the last dose. Contact your doctor immediately in the event of a pregnancy occurring when both the mother and father are taking Xpovio 80 mg twice weekly.This medication can affect fertility (the ability to have children) in both males and women. But it is crucial to utilise birth control to avoid pregnancy since Xpovio 80 mg twice weekly could harm a baby who is not yet born.Don't breastfeed during the course of this medicine or for a minimum of one week after the last dose.It is not permitted to be used for anyone who is under 18 years old.

How to take Xpovio 80 mg?

The doctor will run tests to determine if Xpovio 80 mg twice a week is the appropriate treatment for your needs.Follow the instructions on the prescription label and go through all medication guides or instruction sheets. Your doctor may alter the dosage. Be sure to take your dosage exactly as directed.Xpovio 80 mg twice weekly is usually taken on certain days and is usually taken once or twice a week. Follow the instructions of your physician attentively regarding the best time and method to take this medicine along with dexamethasone or bortezomib.

Your physician will decide how long you will be treated with Xpovio 80 mg twice a week and dexamethasone.Use Xpovio 80 mg once a week with a full glass of drinking water. Suck the tablet in whole, and don't crush, chew, or break the tablet.If you experience vomiting shortly after having taken Xpovio 80 mg twice a week, don't take a second dose. The next dose should be taken as scheduled.There are additional medications to treat nausea, vomiting, infections, or nausea. Take these medicines for the duration your doctor prescribes.There is a chance that you will contract infections more frequently, even fatal or serious infections. You'll need regular medical tests. There is a possibility of needing a transfusion if your blood platelets become too low.

The sodium levels in your blood are required to be checked. If they are way too low, your physician might prescribe salt pills or intravenous (IV) fluids to help keep you from becoming dehydrated.Get plenty of fluids to prevent dehydration. Eat enough calories in order to prevent becoming overweight.Xpovio 80 mg twice a week could affect your appetite and capacity to consume food. The weight of your body will be measured prior to or during your treatment to ensure you're not losing weight when taking this medication.At room temperature, without moisture or heat. Store each Xpovio 80 mg, twice weekly, tablet within the package until the point of taking your dosage.

What happens if I miss a dose?

Do not miss the missed dose, and take the next dose at the normal time. Don't take two doses at the same time.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Avoid driving and other hazardous activities until you are aware of how Xpovio 80 mg twice a week can affect you. The way you react could be impaired.

Interaction with other drugs

Other medications may interact with Xpovio 80 mg twice weekly, including prescription and non-prescription drugs, vitamins, and herbal supplements. Discuss with your physician the other medicines you are taking.




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