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Generically: Pioglitazone (oral) (oral) PYE-o-GLITZ-a-zone
Name of the Brand: Actos
Dosage Format: Oral tablet (15 mg, 30 mg, 45 mg)
The class of Drug: Thiazolidinediones

What Is Pioglitazone?

Pioglitazone is used in conjunction with exercise and diet to help improve blood sugar control in people who suffer from type 2 diabetes. Pioglitazone is not used to treat type 1 diabetes.Pioglitazone can also be used for reasons not mentioned in this medication guide.

Side effects Of Pioglitazone

See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, and swelling of your lips, tongue, throat, or face,Stop using pioglitazone immediately and call your doctor immediately. If you experience signs of damage to your liver: nausea, stomach pain in the upper part of the stomach, itching, lack of appetite, dark urine, clay-colored coloured, and jaundice (yellowing of the eyes or skin).

Pioglitazone may cause serious side effects. Consult your doctor immediately. If you suffer from:

  • Breathlessness (especially in a lying position) uncommon fatigue, swelling, and rapid weight gain.
  • Urine that is pink or red, hard or painful urination, and a new or more intense urge to go to the bathroom;
  • Vision changes,
  • Suddenly, you feel a sudden discomfort in your hand, foot, or arm.

A few people who took pioglitazone suffered bladder cancer; however, it is unclear if pioglitazone is the cause.

Common adverse effects of pioglitazone could include:

  • Headache;
  • Muscle pain;
  • Signs of a cold, like a stuffy nose, sinus pain, coughing, and a sore throat.

This isn't a complete list of possible side effects, and other side effects could occur. Contact your physician for advice regarding medical effects. You can report any symptoms to the FDA at 1-800-FDA-1088.


Pioglitazone could cause or exacerbate chronic heart problems. It is not recommended to use this medication if you suffer from serious or uncontrolled heart failure.Stop taking this medication and contact your doctor immediately if you experience shortness of breath (especially while lying down), excessive swelling, fatigue, or a rapid increase in weight.

Before you Take this Drug

Pioglitazone should not be used in the event that you are allergic to pioglitazone or suffer from:

  • Heart failure that is severe or uncontrolled severe or uncontrolled heart failure
  • Diabetic ketoacidosis (call your doctor for treatment).

This medication can increase the risk of developing bladder cancer. cancer. Consult your physician regarding your particular risk.

Inform your doctor if you were ever diagnosed with:

  • Congestive heart failure or coronary heart diseases;
  • A heart attack and stroke;
  • Eye issues result from the disease of diabetes;
  • Bladder cancer
  • The liver condition.

Pioglitazone could increase your risk of developing serious heart issues. If you don't treat your diabetes, it may also cause damage to your heart and other organs. Consult your doctor about the dangers and advantages of the drug.

Follow the instructions of your physician regarding the use of this medication when you are pregnant or are planning to become pregnant. Controlling diabetes is crucial during pregnancy, and being diagnosed with high blood sugar levels could cause issues for both the mother and the child.Pioglitazone can stimulate ovulation in women who are premenopausal and could increase the chance of an unintentional pregnancy. Consult your doctor regarding your potential risk.

Women are more likely to suffer fractured bones during the use of pioglitazone. Consult your doctor about ways to maintain your bones' health.It might not be safe to breastfeed while taking this medication. Talk to your doctor about any risks.Pioglitazone is not permitted for use by anyone who is younger than

How to take Pioglitazone?

Follow the directions on the prescription label and review all medication guides and instruction sheets. Your doctor may alter your dosage. Make sure you take the medication precisely as prescribed.Pioglitazone is typically taken every day, whether or not food is included.

There is a possibility that you are suffering from insufficient levels of blood sugar (hypoglycemia) and feel extremely hungry, dizzy, angry, and anxious. You may also feel confused or even shaky. To cure hypoglycemia, consume or drink quick-acting sources of sugar (fruit juice crackers, hard candy raisins, apricots, or other non-diet drinks).The doctor might prescribe a glucose injection kit in the event that you suffer from severe hypoglycemia. Make sure that your family members or your closest friends know the procedure to administer the injection in an emergency.

The levels of blood sugar are affected when there is illness, stress, surgery, drinking alcohol, exercise, or by skipping meals. Consult your physician prior to making changes to your medication or dosage schedule.Pioglitazone is just one component of a treatment plan that may comprise exercise, diet, weight control, blood sugar testing, and other medical treatments. Follow the instructions of your physician precisely.Keep the bottle at room temperature, far from heat, moisture, and light. Make sure the bottle is tightly shut when not in use.

Details on Dosage

Usual Adult Dose for Diabetes Type 2:

Patients with no congestive heart disease:
The initial dosage is 15, 30, or even 30 mg every day.
Patients with chronic heart disease (New York Heart Association, NYHA classes I and II):
Initial dose: 15 mg taken orally every day.
Maintenance dosage of 15 mg to 45 mg once per day based upon the glycemic response as measured by HbA1c
Maximum dosage of 45 mg, taken orally at least once per day.
This drug has an antihyperglycemic action only when it is used in conjunction with endogenous insulin and is therefore not likely to be effective for those suffering from type I diabetes or diabetic ketoacidosis.
Patients receiving insulin secretagogue or insulin might have to lower the dosage of insulin or the insulin secretagogue in the event of hypoglycemia.
Use: As an addition to exercise and diet to increase glycemic control in adult patients with type 2 diabetes mellitus in various clinical situations

What Happens If I Miss a Dose?

You should take the medication as quickly as you can. However, avoid your missed dose if it's nearing the time to take the next dose. Don't take two doses at a time.

What Happens If I Overdose?

It is recommended to seek medical attention in the event of an emergency. You can also call to the Poison Helpline at 1-800-222-1222. There are signs that you are suffering from low blood sugar, like intense weakening, blurred vision, sweating, difficulty speaking, tremors, stomach pain, confusion, and seizures (convulsions).

What Should be Avoided?

Do not drink alcohol. It reduces blood sugar levels and could interfere with your treatment for diabetes.

Interaction with Other Drugs

Tell your doctor if you use insulin. Pioglitazone taken while you're using insulin can increase your risk of developing serious heart issues.

Pioglitazone is a drug that can be affected by a variety of drugs. This includes prescription as well as over-the-counter medications, vitamins, and herbal supplements. Not all interactions are included in this list. Discuss with your physician your current medications and any other medications you are about to start or stop taking.



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