The Web Health


Sudafed Sinus: 12 Hour Pressure + Pain

Generic name: naproxen and pseudoephedrine [na-PROX-en-and-soo-doe-e-FED-rin]
Brand names: Aleve Cold and Sinus, Aleve Sinus and Headache, Aleve-D Cold and the Sinus, Sudafed Sinus 12 Hour Pressure + Pain, Sudafed PSE
Classification of drugs: upper respiratory combinations

What is Sudafed Sinus 12 Hour Pressure + Pain?

Naproxen is a nonsteroidal anti-inflammatory medication (NSAID). Pseudoephedrine is a decongestant. Sudafed Sinus 12 Hour Pressure + Pain Medicine treats sinus congestion, stuffy nose headaches, fever, and minor pains and aches caused by common colds and flu. Sudafed Sinus 12 Hour Pressure + Pain can be used for other purposes not covered in this medication guide.

Side effects of Sudafed Sinus 12 Hour Pressure Pain

Seek medical attention immediately. If you notice symptoms of an allergic reaction (hives, breathing difficulties, or feeling lightheaded or swollen in your throat or face) or a severe skin reaction (fever, sore throat, burning eyes, skin irritation, red or purple skin eruption that can spread and cause peeling and blisters),

Seek emergency medical assistance. If you're experiencing symptoms of stroke or heart attack, such as chest pain spreading to your shoulder or jaw, sudden weakness or numbness on one side of your body, slurred speech, leg swelling, or feeling breathless,

Stop taking Sudafed for sinus pressure and pain. Call your doctor immediately if you suffer from:

  • Severe dizziness or nervousness; trouble sleeping;
  • Swelling and rapid weight gain
  • Breath shortness;
  • New or worsening stomach pain or
  • Signs of stomach bleeding: bloody or tarry stool, coughing up blood, or vomit that resembles coffee grounds.

Common adverse consequences of sudden sinus pressure and pain could include:

  • Heartburn, stomach pains, nausea, vomiting;
  • Dizziness
  • Sleep problems (insomnia); or
  • Feeling anxious or feeling anxious or

This is not an exhaustive list of side effects. Other side effects could occur. Contact your doctor to seek medical advice regarding adverse effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.


Naproxen may increase your chance of suffering a fatal heart attack or stroke. Do not take this medicine before or after heart bypass surgery (coronary bypass grafts for arteries, also known as CABG). Naproxen may cause bleeding in the stomach or intestines and can cause fatal bleeding.

Before you take this drug

Naproxen may increase the risk of a fatal stroke or heart attack even when you don't have any risk factors. Avoid using Sudafed Sinus 12 Hour Pressure & Pain prior to or following the procedure for heart bypass (coronary bypass grafts for artery bypass, or CABG). Naproxen can also trigger digestive bleeding in the stomach, which could be fatal. These conditions can happen at any time while taking naproxen, particularly in older people. You should not take this medication if you are allergic to pseudoephedrine or naproxen or if you've ever suffered an asthma attack or a severe allergic reaction following taking aspirin or an NSAID. Do not take Sudafed for sinus pressure and pain if you've used an MAO inhibitor within the past 14 days. A risky drug interaction may occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine, as well as other MAO inhibitors.

Ask your doctor or pharmacist to determine if this medication is suitable for use in the event that you suffer from:

  • heart disease, high blood pressure, diabetes;
  • A stroke or heart attack;
  • A stomach ulcer or bleeding
  • asthma;
  • an thyroid disorder;
  • Prostate enlargement, urinary tract issues,
  • kidney or liver disease or
  • If you consume three or more alcoholic drinks in a day.

Do not take Sudafed for sinus pressure and pain during pregnancy unless your physician advises you to. Utilizing an NSAID within the final 20 weeks of pregnancy could cause harm to the unborn baby or cause pregnancy-related complications. Talk to your doctor before using this medication if you are nursing. Not recommended for use by anyone younger than 12 years old.

How to take it?

Use only as directed on the label or as directed by your physician. Choose the dose that works for treating your condition. Suck the tablet whole and don't crush, chew, or break it. Drink this medicine with an entire glass of water. Take it with milk or food if this medicine causes a stomach upset. If you're planning to have any kind of surgery, inform the surgeon prior to surgery if you've taken this medication in the last few days. Consult your physician if you experience a fever that lasts longer than 3 days or if your symptoms do not get better after seven days of using this medication. Keep the room at a temperature that is comfortable, far from humidity and heat.

What happens If I miss a dose?

Because cold medicine is taken whenever needed, you may not be following a dose schedule. Do not miss any doses in the event that it's nearing time to take the next dose. Don't take two doses at the same time.

What happens if I overdose?

Get medical attention immediately or contact the poison help line at 1-800-222-1222.

What should be avoided?

Do not drink alcohol. It can increase the risk of bleeding from your stomach. Do not take aspirin unless a doctor has instructed you to. Consult your doctor or pharmacist prior to using any different cough or cold medications that could include similar ingredients.

Interaction with other drugs

Consult your physician before taking Sudafed Sinus 12 Hour Pressure and Pain if you use an antidepressant. Taking certain antidepressants along with an NSAID can cause bleeding or bruises easily.

Consult your physician or pharmacist before taking Sudafed Sinus 12 Hour Pressure and Pain in conjunction with any other medication, particularly:

  • A blood thinner (Warfarin, Coumadin, Jantoven);
  • Blood pressure or heart medication, such as diuretics or "water pills"; or
  • Steroid medicine (such as prednisone).

This list isn't complete. Other medications can influence Sudafed Sinus 12 Hour Pressure and Pain, such as prescription and non-prescription medications, vitamins, and herbal products. Not all possible interactions with drugs are listed here.