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Phenergan (rectal)

Generical name: promethazinea-zeen
Names of brands: Phenergan, Promethegan, and Phenadoz rectal
Drug classes: antihistamines, phenothiazine antiemetics

What is Promethazine Rectal?

Promethazine is used to treat allergy symptoms like itching, runny nose, itchy or dry eyes, hives, and dry skin eruptions. Promethazine can also help prevent motion sickness and is a treatment for nausea, vomiting, or pain following operations. It can also be employed as a sedative and sleeping aid. Promethazine should not be used in the treatment of signs of asthma, pneumonia, or any other respiratory tract infection. Promethazine is also used for different purposes that are not mentioned in this guide.

Side effects of Promethazine rectal

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms or warning signs of an allergic response, like hives, trouble breathing, or swelling of your lips, face, and tongue.

Phenergan may cause serious side effects. Consult your physician immediately. If you suffer from:

  • Extremely sleepiness as well as shallow or weak breathing;
  • A feeling of lightheadedness, as if you're about to pass out.
  • Confusion, agitation, hallucinations, and nightmares;
  • Seizure (convulsions);
  • Rapid or slow heartbeats;
  • Jaundice (yellowing of the eyes or skin);
  • Muscles that are not controlled in your facial muscles (chewing, lip-smacking, mouth movement, frowning, blinking, or eye movements);
  • Bleeding or easy bruising (nosebleeds and bleeding gums);
  • Suddenly feeling weak or sick, fever, chills, sore throat or mouth sores, red or swollen gums, difficulty swallowing, or
  • Nervous system reactions that are severe, very rigid (rigid) muscles with high fever, sweating, as well as confusion and quick or irregular heartbeats as if you're about to faint

Common adverse effects of phenergan include:

  • Drowsiness, dizziness;
  • Ringing in your ears
  • Double vision;
  • Feeling anxious;
  • Dry mouth or
  • Tiredness, sleep problems (insomnia)

This isn't an exhaustive list of all the side effects. Others could happen. Discuss with your doctor any unusual or unpleasant side effects. You can report any adverse symptoms to the FDA at 1-800-FDA-1088.

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Prednisone, Trazadone, Hydroxyzine, Ondansetron, Lorazepam, Fluticasone Nasal, and Loratadine


Promethazine should never be administered to children younger than two years old. Promethazine could cause serious breathing problems or even death for very young children.

Before taking this medication

Promethazine is not recommended for children younger than 2 years of age. Promethazine may cause breathing issues or even death for children younger than 2 years old. Follow the directions of your physician before administering this medication to children, regardless of age. It is not recommended to use this medicine if you are allergic to promethazine or similar medications like mesoridazine, fluphenazine, perphenazine, and prochlorperazine. trifluoperazine or thioridazine.

Speak to your doctor if you have ever suffered from:

  • Asthma, chronic obstructive respiratory illness (COPD), sleep apnea, or any other breathing disorders.
  • A background of seizures;
  • An immune system that is weak (bone-marrow depression);
  • Glaucoma;
  • Prostate enlargement or urinary problems;
  • Stomach ulcer or obstruction
  • The heart condition, also known as excessive blood pressure,
  • Liver disease or
  • If you've ever experienced any serious adverse side effects when using promethazine or any other phenothiazine,

Inform your doctor if you are nursing or pregnant.

How to take Promethazine rectal?

Follow the instructions on the prescription label and go through all medication guides or instructions sheets. Follow the medication precisely as directed. Do not consume promethazine through the mouth. It's only for use within your rectum.

It is recommended to get rid of your bladder and bowels prior to taking the suppository of promethazine.Take off the wrapper on the suppository prior to inserting it. Do not handle the suppository for too long, or it could melt in your hands.

To get the most benefit from the suppository, lay down on your back after inserting it. Then leave the suppository for several minutes. The suppository is likely to melt after being inserted, and you will not feel any discomfort when holding it. Be sure to not go to the bathroom right after you've inserted the suppository. Consult your physician if symptoms do not improve or if symptoms get worse when you take promethazine.

This medication can cause unexpected results in certain tests. Be sure to inform any doctor treating your condition that you are taking promethazine rectal. Keep the suppositories for rectal storage in the refrigerator, but do not allow them to be frozen.

What happens if I miss the dose?

Utilize the medication as soon as you can; however, do not miss any missed doses if it's close to the time for the next dose. Do not take two doses in one go.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

The symptoms of an overdose can include hyperactive reflexes or a loss of coordination. extreme drowsiness or weakness, weakening eyes, dilation of pupils, shallow or weak breathing, or seizures (convulsions).

What should be avoided?

The medicine could affect your reactions or thinking. Be aware if you are driving or engaging in any activity that requires you to be aware. Do not get up too fast from a lying or sitting position, as you may get dizzy. Make sure to get up slowly and steadily to avoid falling.

Drinking alcohol can intensify the effects of promethazine in certain ways.

Avoid exposure to the sun as well as tanning beds. Promethazine may cause burns more quickly. Protect yourself with protective clothes and apply sunblock (SPF 30 or more) in the outdoors.

Interaction with other drugs

Utilizing promethazine rectal, along with other medications that cause drowsiness, can cause more of this. Consult your physician before taking opioids, sleeping pills, a muscle relaxer, or medication for anxiety and seizures.

Other drugs can interact with promethazine rectal, such as prescription and over-the-counter medicines, vitamins, and herbal products. Discuss with your physician all the other medicines you are taking.




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