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Metoclopramide (nasal)

Generic name: Metoclopramide Nasal [Met-oh KLO-pr-a-mide]
Brand name: Gimoti
Dosage form: nasal spray (15 mg/actuation)
Classification of drugs: stimulants for the GI tract, antiemetics

What is Metoclopramide?

Metaclopramide Nasal is prescribed to adults who have diabetes for symptoms such as slow stomach emptying, stomach pain, and nausea.This medication guide does not list all possible uses of metoclopramide.

Side effects of Metoclopramide

If you experience any of the following symptoms of an allergy: blisters, sores in your mouth, difficulty breathing, swelling on your lips, face, tongue, or throat, hives, or a rash,If you experience any of the following signs of a severe movement disease, it is important to call your doctor immediately. This may happen within 2 days after starting treatment.

  • You may experience tremors in your legs or arms.
  • Uncontrolled facial movements (like lip-smacking, frowning and tongue movement ) can lead to unintended results such as lip-smacking, frowning and tongue movement.
  • Trouble breathing
  • Any new or abnormal muscle movements that you can't control

Metoclopramide can cause severe side effects. If you experience:

  • Confusion; thoughts of harming or killing yourself.
  • Slow or jerky movements of the muscles, balance problems, or difficulty walking
  • Mask-like appearance on your face
  • A seizure;
  • Anxiety is a feeling of agitation. It can be characterized by a jittery feeling, difficulty sleeping, and trouble remaining still.
  • Rapid weight gain, swelling, and shortness of breath
  • Missed menstrual cycles
  • Breast swelling, nipple discharge;
  • Severe nervous system reaction: very stiff muscles (rigid), high fever, sweating, and confusion. Fast or irregular heartbeats. Tremors. Feeling like you may pass out.

Side effects associated with metoclopramide include:

  • Unpleasant taste
  • Feeling tired

There may be other side effects. For medical advice on side effects, call your doctor. Please report side effects by calling FDA's Toll Free hotline: 1-800-FDA-1088.

Similar/related drugs

Botox, omeprazole, famotidine, pantoprazole, ondansetron, hydroxyzine, and diclofenac

Warnings

Metoclopramide in high doses and long-term use can lead to a severe movement disorder. This may be irreversible. You are more likely to get this condition if you have been taking metoclopramide for a long time, particularly if you're a woman or older. DO NOT USE MORE METOCLOPRAMIDE NASIL THAN IS RECOMMENDED OR FOR A LONGER PERIOD THAN 8 WOMEN. If you experience uncontrollable movements of your tongue, lips, eyelids, face, arm, or leg, call your doctor immediately.

Before you take this drug

If you're allergic to metoclopramide or have any of the following:

  • Tardive Dyskinesia
  • Stomach or intestinal issues such as bleeding or a perforation in the stomach or intestines;
  • Epilepsy
  • An adrenal gland tumor (pheochromocytoma);
  • If you have ever experienced muscle problems following the use of metoclopramide or other similar medications,

If you've ever:

  • Liver or kidney disease
  • Problems with muscular movements
  • Congestive heart failure, or an abnormal heart rhythm;
  • High blood pressure
  • Seizures;
  • Breast Cancer
  • Depression or mental illness
  • Parkinson's disease.

Tell your doctor if, after being tested for CYP2D6, an enzyme that helps to break down some medicines in the human body, you have been told that you are a bad metabolizer.Inform your doctor that you're pregnant. Metoclopramide can harm an unborn child if used during late pregnancy.A doctor can tell you if breastfeeding is possible while taking metoclopramide. Tell your doctor about any unusual movements, yellow or pale skin, dark urine, or fever in a nursing infant.No one under 18 may use this product.

How to take Metoclopramide?

Read all the instructions or guides that come with your medication and follow all the directions. Follow the directions on your prescription label.Spray the nasal spray 30 minutes prior to each meal and before bed.Usually, metoclopramide nasal is prescribed only for 2–8 weeks.Never use metoclopramide in higher doses than recommended or for longer than 8 weeks. Metoclopramide may cause serious movement disorders that are not reversible. You are more susceptible to this condition if you take metoclopramide for a long time, particularly if you're a woman or older.Do not use metoclopramide (oral, nasal, or injection) for longer than 12 weeks.Keep it away from heat and moisture in an airtight container at room temperature. Even if the medicine is still inside, throw away the container four weeks after it has been opened.You may experience unpleasant withdrawal symptoms after stopping metoclopramide. These include headaches, nausea, and nervousness.

What happens if I miss the dose?

Do not take two doses at once. Use only one dose at a time.Do not spray a second dosage if you're not sure that you got the full amount of medicine when you sprayed it into your nostrils. Do not use this medicine until you have taken your scheduled next dose.

What happens if I overdose?

Call the Poison Help Line at 1-800-222-1222 or seek emergency medical care. Overdose symptoms include confusion or uncontrolled movements of the muscles.

What happens if I overdose?

Don't drink alcohol.Do not drive or engage in hazardous activities until you have determined how you will be affected by metoclopramide. You may be unable to react properly.

Interaction with other drug

This effect can be worsened by using metoclopramide with drugs that cause drowsiness. Before taking an opioid, sleeping pills, muscle relaxers, anxiety medications, or medicines for seizures or anxiety, consult your doctor.

Inform your physician of all medications you are currently taking. Metoclopramide may interact with numerous substances, including:

  • Blood pressure medications
  • Insulin;
  • Medicine to treat mental illnesses or depression
  • Medicine to treat Parkinson’s disease or restless legs syndrome
  • MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine and many others.

Metoclopramide may be affected by many drugs not listed here. These include prescription, over-the-counter, herbal, and other products. This list does not include all possible drug-drug interactions.