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What is Hysingla ER?
Hysingla is an opioid pain reliever.Hysingla Extended Release Tablets are used to treat severe pain around the clock.Hysingla ER should not be used as needed for pain.
Side effects of Hysingla ER
If you experience any of the following symptoms of an allergy to Hysingla: hives, difficulty breathing, swelling of the face, lips, or tongue, or if your skin becomes red, itchy, or swollen, call 911.If you take opioid medicine, it can cause your breathing to slow down or stop. Death may result. If you have long pauses in your breathing, blue lips, or are hard to awaken, someone caring for you may want to give you naloxone.
Hysingla ER should be stopped, and you should call your doctor immediately if:
- Sighing, noisy breathing, shallow breathing, or breathing that stops while sleeping
- A slow heartbeat or a weak pulse.
- Pain or burning after urinating;
- Confusion, tremors, and severe drowsiness;
- A feeling of lightheadedness, as if you could pass out.
- Low cortisol levels cause nausea, vomiting, loss of appetite, dizziness, and worsening fatigue or weakness.
- High levels of serotonin: agitation and hallucinations; fever, sweating, or shivering; fast heartbeat; muscle stiffness or twitching; loss of coordination.
Severe breathing problems are more common in elderly adults, especially those with wasting syndrome and chronic breathing disorders.If you experience symptoms of serotonin disorder, including agitation, hallucinations, fever, sweating, or shivering, rapid heart rate, muscle stiffness, and twitching, You may also experience nausea, vomiting, diarrhea, orMen or women may be affected by long-term opioid use. The effects of opioids on fertility may not be permanent.
Hysingla ER may cause side effects such as:
- Constipation, nausea, vomiting;
- Feeling tired, dizzy, or drowsy
- Headache
- Cold symptoms include a stuffy nose and sneezing.
There may be other side effects. For medical advice on side effects, call your doctor.Contact the FDA by dialing 1-800-FDA-1088 in order to report adverse side effects.
Warnings
You may experience breathing problems if you take hydrocodone. Hysingla ER should never be taken in higher doses or for longer periods than prescribed. The extended-release tablet should not be crushed, broken, or opened. Avoid exposure to potentially deadly doses by swallowing the entire pill.Even at low doses, hydrocodone can become habit-forming. Hysingla ER should never be shared with anyone, especially if they have a history of addiction or drug abuse. Keep the medicine in a safe place that others can't reach.Misuse of opioid medication can cause addiction, overdose, or death. Store the Hysingla ER away from others.Inform your doctor that you are expecting. If the mother took hydrocodone during pregnancy, it can cause severe withdrawal symptoms for the newborn.You can experience fatal side effects if you combine opioid medication with alcohol or other drugs that make you drowsy or slow down your breathing.
Before you take this drug
Hysingla ER should not be used if:
- Severe asthma or breathing problems
- A blockage of the intestines or stomach
Tell your doctor if:
- Sleep apnea, breathing problems
- A head injury, brain tumor, or seizures;
- Mental illness or drug or alcohol abuse;
- Urination problems
- Liver or kidney disease
- You may have problems with your thyroid, gallbladder, or pancreas.
- A heart rhythm disorder called long QT syndrome.
Your baby may experience withdrawal symptoms after being exposed to opioids while you were pregnant.Babies born dependent on opioids may need medical treatment for several weeks.If you are nursing, consult your doctor before using Hysingla ER. Inform your doctor if the baby is drowsy or has a slow breathing rate.
How to take Hysingla ER?
Hysingla ER can be addictive, even when taken at the recommended dose. Read all the instructions on the prescription label. Hysingla should never be taken in higher doses or for longer periods than prescribed. If you are feeling the urge to take this medication more often, tell your doctor.Do not share opioid medication with anyone, especially if they have a history of drug abuse. Misuse can lead to addiction, overdose, or death. Store the medication away from others. It is illegal to sell or give away opioid medication.If you've recently taken a similar opioid pain medication and your body has become tolerant to it, then the dose that is needed may be different. Speak to your doctor if you're not sure if you're opioid-tolerant.Do not break or crush a tablet. Instead, swallow the entire tablet to avoid a potentially deadly dose. Do not crush or break a Hysingla ER Tablet to inhale powder or mix the tablet into a liquid for injection into your vein. It can be fatal.
If you suddenly stop taking this medication, you may experience severe withdrawal symptoms. Your doctor can tell you how to stop taking Hysingla ER safely.Store away from moisture, heat, and light. Track your medication. Be aware of anyone who is misusing your medicine or using it without a valid prescription.Keep leftover opioid medications out of the reach of children. One dose of this medication can be fatal for someone who uses it incorrectly or accidentally. You should ask your pharmacist about a drug disposal program. If there isn't a take-back program available, flush any unused medication down the toilet.
Details on dosage
Adult dose for chronic pain:
These dosing suggestions are only suggested approaches for what is in fact a series of clinical decisions made over time. Each patient should be treated individually.
As the first opioid analgesic for patients who do not tolerate opioids:
Hysingla ER Extended-Release Tablets: Initial dosage: 20 mg orally once every 24 hours
Comments:
Use of higher doses at the beginning in patients not tolerant to opioids can cause respiratory depression that is fatal. Monitor patients for respiratory depression closely, especially within the first 24 hours.
A patient who is opioid-tolerant has received for at least one week: oral morphine, 60 mg/day; fentanyl patches, 25 mcg/hour; oral oxycodone, 30 mg/day; oral hydromorphone, 8 mg/day; oral oxymorphone, 25 mg daily or an equivalent dosage from another opioid is suggested for optimal treatment.
What happens if I miss the dose?
Hysingla ER treats pain, so you won't miss a dosage. If it's almost time to take your next dose, skip any missed doses. Never take two doses in one go.
What happens if I overdose?
Call the Poison Help Line at 1-800-222-1222 or seek emergency medical care. An overdose of hydrocodone can be deadly, especially if it is taken by a child or someone who has not been prescribed the drug.You may be advised by your doctor to carry naloxone with you (a medication that reverses an opioid overdose). If you stop breathing or if you don't awaken, someone caring for you may administer naloxone. You must still call for emergency medical assistance, and your caregiver may have to perform CPR on you while they wait.Naloxone can be purchased at any local pharmacy or health department. Make sure anyone who cares for you is aware of where and how you store naloxone.
What should be avoided?
Don't drink alcohol. Side effects and death can occur.Do not drive or engage in hazardous activities until you have determined how Hysingla ER affects you. Drowsiness or dizziness can cause accidents or serious injuries.
Interaction with other drug
If you stop or start taking certain medicines, you may experience breathing problems or withdrawal. You should tell your doctor if other medicines are being used, such as antifungal, blood pressure or heart medication, seizure medications, or medication to treat HIV and Hepatitis C.
Opioids can interact with other medications and cause serious side effects, or even death. Tell your doctor if you use:
- Cold or allergy medicine, bronchodilator asthma/COPD medications, or diuretic (water pill);
- Medicines to relieve symptoms of motion sickness, irritable bowel syndrome or overactive bladder.
- Other Opioids: opioid pain medication or prescription cough medicine
- A sedative similar to Valium: diazepam (or alprazolam), lorazepam (or Xanax), Klonopin (or Versed), and others.
- Drugs that make you sleepy or slow down your breathing—a sleeping tablet, a muscle relaxer, or medicine for mood disorders or mental illnesses;
- Drugs that alter serotonin levels—a stimulant or medicine to treat depression, Parkinson's disease, migraine headaches, or serious infections
This list is incomplete. Hydrocodone may interact with other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. This list does not include all possible interactions.