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Human papillomavirus (HPV) vaccine, 9-valent

Generic Name: Human Papillomavirus (HPV) vaccine, 9-valent

Brand name: Gardasil 9
Dosage form: intramuscular suspension (9-valent)
Drug class: viral vaccines

What is Human papillomavirus (HPV) vaccine, 9-valent?

Human papillomavirus is a sexually transmissible disease that can lead to genital lesions. HPV may also cause nasal cancer as well as various cancers in the cervix or vagina.The HPV 9-valent vaccination is given to children and adults aged 9 to 45 in order for them not to develop genital warts or cancers that are caused by certain HPV types.This vaccine can be given to you even if your genital warts have been present for some time or if you've had an abnormal pap test or a positive HPV result in the past. This vaccine does not treat active warts on the genital area or HPV-related tumors. It will also not cure HPV.The HPV 9-valent vaccination prevents only diseases caused by HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58. This vaccine will not protect against diseases caused by any other HPV types.The Centers for Disease Control and Prevention recommend HPV vaccination for boys and girls aged 11 and 12 years. The vaccine is recommended for teenage girls and boys who haven't received the HPV vaccine yet or haven't completed their booster shots.The HPV 9-valent vaccination may not protect everyone from disease.The HPV 9-valent vaccination may be used in other ways not mentioned in this guide.

Side effects of Human papillomavirus (HPV) vaccine, 9-valent

If you experience any of the following signs of an allergic reaction: hives, difficulty breathing or swelling of lips, face, tongue or throat. Seek medical assistance immediately.Track any side effects that you experience after getting this vaccine. You will need to inform your doctor of any side effects you experience after receiving the first dose.After receiving this vaccination, you may feel faint. Some individuals have experienced seizures after receiving the vaccine. You may be asked to stay under observation for the first 15 minutes following the injection.The vaccine is more effective at protecting you against HPV than the development of cancer. This vaccine, like all medicines, can have side effects, but the risks of serious side effects are extremely low.

Side effects associated with the 9-valent human papillomavirus vaccine (HPV) may include:

  • Pain, swelling, redness, itching, and a lump at the site of the injection;
  • Nausea diarrhea;
  • Headache;
  • Fever;
  • Sore throat
  • Dizziness;

There may be other side effects. For medical advice on side effects, call your doctor. Report the side effects of vaccines to the US Department of Health and Human Services by calling 1-800-822-7967.

Similar/related drugs

Gardasil 9; Cervarix; human papillomavirus vaccine


If you had a severe allergic reaction to the first dose, then you should not get a booster shot.You may feel faint for the first 15 minutes following this vaccination. This vaccine has caused seizures in some people.

Before you take this drug

If you had an allergic reaction that was life-threatening after your first injection, then you should not get a booster shot. If you are suffering from a high temperature, this vaccine may not be available to you.

The HPV 9-valent vaccination does not protect against sexually transmissible diseases like chlamydia and gonorrhea. It also doesn't protect against HIV, syphilis, or trichomoniasis.

Tell your doctor about any of the following:

  • An allergic reaction to polysorbate 80 or other vaccines
  • A weak immune system, caused by diseases such as HIV and cancer.
  • Treatment with steroids, cancer medicines, or other drugs can lower your immune system.

Inform your doctor if you are pregnant or nursing.You may find your name on a registry for pregnant women to monitor the effects of the HPV 9-valent vaccination on the child.

How to take Human papillomavirus (HPV) vaccine, 9-valent?

The HPV 9-valent vaccination is administered as an injection into the muscles of your upper arm, thigh, or leg. This injection will be given by a healthcare provider.The HPV 9-valent vaccination is administered in two or three shots. The first dose can be given at any age between 9 and 45. The second shot is administered 2–12 months after the first. Six months after the first shot, a third dose can be administered.If you do not receive the full recommended dose of this vaccine, your protection against disease may be compromised.The HPV 9-valent vaccination should not replace a pelvic exam, pap smear, anal, or head and neck exam for screening cervical, head, and neck cancer.

Details on dosage

Adult dose for human papillomavirus prophylaxis:

Females up to 25 years of age: 0.5 mL intramuscularly at 0, 1, and 6 months.
Males and females up to the age of 26: 0.5 mL intramuscularly at 0, 2, and 6 months
Gardasil 9(R):
Males and females up to 45 years old: 0.5 mL intramuscularly at 0, 2, and 6 months
Uses: To prevent cervical cancer, vulvar cancer, and anal cancer in females caused by the human papillomavirus. Also, to prevent anal cancer in males and genital warts and anal intraepithelial neoplasia in males,

The usual pediatric dose for human papillomavirus prophylaxis

Females aged 9–25 years: 0.5 mL intramuscularly at 0, 1, and 6 months
Males and females aged 9 to 26 received 0.5 mL intramuscularly at 0, 2, and 6 months.
Gardasil 9(R):
Males and females aged 9–14 years old: 0.5 mL intramuscularly at 0, 6–12 months, and 2 doses.
Males and females aged 9–14 years old: 0.5 mL intramuscularly at 0, 2, and 6 months.
Females and men aged 15–45 years: intramuscular injection of 0.5 mL at 0, 2, and 6 months.
For patients aged between 9 and 14: If a second dose of Gardasil 9 (R) is administered earlier than five months after a first dose, give a third dose no sooner than four months after completing the second dose.
Uses: To prevent cervical cancer, vulvar cancer, and anal carcinoma caused by the human papillomavirus in females. Also, to prevent anal cancer, genital neoplasia, and genital warts in males

What happens if I miss the dose?

If you are behind on your booster doses or have missed one, contact your doctor. The next dose should be administered as soon as you can. There is no need to start again.

What happens if I overdose?

It is very unlikely that this vaccine will cause an overdose.

What should be avoided?

If your doctor prescribes any restrictions regarding food, beverage, or activity, follow their instructions.

Interaction with other drug

You can get more information from your vaccination provider, doctor, or pharmacist. You can get more information from your local department of health or the Centers for Disease Control and Prevention.