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Xembify (subcutaneous)

Generic name: Immune globulin (subcutaneous) [im-MYOON-GLOB-yoo-lin]

Brand names: Cutaquig, Cuvitru, Hizentra, Xembify
Drug class: Immunoglobulins

What is Xembify?

The drug Xembify (for injection into the skin) is used to treat primary immunodeficiency illnesses.

The drug Xembify can also be employed to address chronic inflammatory demyelinating neuropathy (an auto-immune disorder where an immune system attacks nerves, which causes muscles to weaken and numb). The drug Xembify is also employed for other purposes that are not covered in this guideline.

Side effects of  Xembify

Stop taking Xembify and seek medical emergency help if you are experiencing symptoms that indicate an allergic reaction, such as hives, wheezing, chest tightness, trouble breathing, dizziness, feeling like you could be passing out, or swelling of your lips, face, or tongue.

Zombify could cause serious side effects. See your physician right away If you have:

  • A blood cell disorder characterized by pale or yellowed skin, dark-colored blood, the feeling of fever, weakness, or confusion;
  • Kidney issues: no or little urinary frequency, swelling, an increase in weight, and feeling tired of breath,
  • Issues with the lungs: chest pain, difficulty breathing, blue-colored lips, fingers, or toes;
  • Symptoms of a new fever that are accompanied by symptoms of a new infection include a severe headache, stiff neck, eye pain, and an increase in sensitivity to light.
  • Symptoms of a blood clot: breathing difficulty, chest pain that is accompanied by deep breathing, a rapid heart rate, weakness, or numbness on the opposite part of your body. There may also be swelling, discomfort, or discoloration on the leg or arm.
  • Trouble breathing, wheezing;
  • Bleeding, redness, pain, itching, swelling, or a lump at the site where the medicine was injected.
  • Fever, tiredness, and dizziness;
  • Nausea, vomiting, diarrhea, bloating, and stomach pain;
  • Itching and itching, or any other skin issues;
  • Symptoms of the cold and flu, such as nasal stuffiness, sneezing, a sore throat, and coughing;
  • Headache, migraine,
  • Discomfort anywhere in your body.

It's not a comprehensive listing of all possible adverse impacts, as other things might occur. Consult your doctor for guidance about medical-related adverse reactions. It is possible to report any adverse allergic reactions or symptoms to the FDA by calling 1-800-FDA-1088.


This medication can lead to blood clots. The risk is greatest when you are older or have blood clots, heart problems, or blood circulation issues. Blood clots can also be more likely to occur during prolonged bed rest, when using birth medications to control them, hormone replacement therapies, and when using an intravenous central (IV) catheter.

Consult your physician immediately. If you experience chest pain, difficulty breathing, heartbeats that are fast, weakness or numbness, a feeling of warmth, swelling, or discoloration of your leg or arm,

This medication can cause harm to the kidneys, especially if you suffer from kidney problems or are also taking certain medications. Inform your doctor immediately if you show symptoms of kidney disease that include swelling, rapid weight gain, and a lack of urine.

Before you take this drug

You shouldn't utilize Xembify in the following situations

  • You've experienced any allergic reactions to Xembify or other blood products;
  • You have a Xembify A (iga) deficiency due to antibodies to iga.

It is possible that you will not be able to take Xembify in the event that you've suffered any allergic reactions to polysorbate or if you suffer from an illness known as hyperprolinemia (a high concentration of a particular amino acid in the blood).

This medication can lead to kidney or blood clots, particularly in older individuals or those with certain medical conditions. Consult your physician if you've ever:

  • Heart conditions or blood circulation issues and "thick blood";
  • A stroke or blood clot
  • Kidney disease;
  • Diabetes;
  • An infection referred to as sepsis;
  • If you take hormones (birth control pills or hormone replacement therapy),
  • If you've been in bed for a long time,
  • If you have an intravenous central (IV) catheter installed.

It is possible to adjust your dose if you have been affected by measles or traveled to a place that is measles-prone.

Don't give the medication to children without medical guidance.

Xembify is created from human plasma donated by donors and may be contaminated with viruses or different infectious agents. Donated plasma is analyzed and treated to decrease the risk of contamination, but there's a chance that it could be a carrier of diseases. Consult your physician about any potential dangers.

How to take Xembify?

Xembify is injected beneath the skin with an injection pump. The medicine is injected via a tube that is placed beneath the skin. Your healthcare professional may instruct you on how to use the medication yourself.

Xembify can be taken every day and occasionally every one to two weeks. Take this medicine regularly to ensure an even amount of medication in your body throughout the day. If you take this medicine at home, you should keep an account of the dates and times you administered the injection, as well as the location where you injected it into your body.

Zombify is best administered slowly. You may require up to eight different catheters for the simultaneous infusion of the medication into different body parts. Your doctor will inform you of the best place on your body to inject the medicine. Make sure to inject in a different area every time you administer an injection. Don't inject the same area twice in the same row.Take note of and follow the instructions for use that come along with your medication. Consult your physician or pharmacist to clarify any instructions.

Make an injection only when you are prepared to administer it. Don't use it when the medication is cloudy, has changed colors, or has particles. Consult your pharmacist about the latest medication. Don't shake the medication bottle, as you risk ruining the medicine.Avoid injecting Xembify into the vein.

You'll need regular blood tests. This medication may affect the results of some other tests that you require. Be sure to inform any doctor treating patients with Xembify. Keep Xembify stored in its original container at room temperature. Beware of light and heat.

It is also possible to store the medicine in the original carton in the fridge. Don't freeze Xembify. Also, dispose of the medicine in the event that it has been frozen.It is necessary to take your medication within a specified number of months. It will be contingent on the way you store the medication (at ambient temperature or in the refrigerator). Be sure to follow the storage guidelines that are included in your prescription. Consult your pharmacist if you have any questions.

Get rid of any medicine that has not been used after the end date printed on the bottle has expired. The contents of each bottle are intended for only one use. Dispose of it after one use, regardless of whether there's still some medicine in it.

Make use of disposable injection tools (needle catheters, tubing, etc.) only once and then put them into a puncture proof "sharps" container. Make sure you follow local or state laws regarding the disposal of the container. Make sure it is out of reach of pets and children.

What happens if I miss a dose?

Contact your doctor for advice when you have missed a dose.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Don't receive any "live" vaccines while using Xembify. The vaccine might not function as effectively and could not completely protect you from diseases. Live vaccinations cover measles, mumps, and rubella (MMR), as well as typhoid, rotavirus yellow fever, varicella (chickenpox), zoster (shingles), and nasal influenza (flu) vaccine.

Interaction with other drugs

Zombify could cause kidney damage, particularly when you are also taking specific medications for osteoporosis, cancer, infections, organ transplant rejection, digestive issues, high blood pressure, or arthritis pain (including Advil, Motrin, and Aleve).

Other medications can affect Xembify, such as prescription and over-the-counter medicines, vitamins, and herbal products. Discuss with your physician all the medicines you are currently taking as well as any medicines you take or stop taking.