Gemifloxacin

What is Gemifloxacin?

The antibiotic fluoroquinolone, or floro-KWINO-line in its full name (pronounced floro-KWINO-lone), is used to fight bacteria within the body. The treatment of different types of bacterial lung infections with gemifloxacin The side effects of fluoroquinolones are often severe or even disabling. Gemifloxacin is only to be used for serious infections that cannot be treated by a more effective antibiotic. This medication guide does not list all possible uses of gemifloxacin.

Side effects of Gemifloxacin

If you experience signs of a severe allergic reaction, such as hives, difficulty breathing, or swelling around your mouth or face, call 911. After just one dose, gemifloxacin may have serious side effects. These include tendon damage, nerve side effects (which could cause permanent nerve injury), mood and behavior changes that are severe (even after a single dose), or lower blood sugar.

Call your doctor immediately if you experience:

• Low blood sugar symptoms include headaches, nausea, dizziness, or sweating.
• Nerve symptoms can include numbness or weakness in the hands, arms, feet, and legs.
• Serious mood or behavior changes—nervousness, confusion, agitation, paranoia, hallucinations, memory problems, trouble concentrating, thoughts of suicide; or
• Signs of a ruptured tendon include sudden pain, swelling, or bruising. Tenderness or stiffness may also be present.

Gemifloxacin can cause damage to the aorta (the main blood vessel of your body) in rare instances. It could cause dangerous bleeding, or even death. If you experience severe pains in your back, chest, or stomach that are constant, seek emergency medical attention.

Stop using the gemifloxacin immediately and contact your doctor if:

• Diarrhoea that is bloody or watery, severe abdominal pain
• Experience rapid or pounding pulses, chest fluttering and shortness of breath; sudden dizziness.
• The first signs of any skin irritation, however mild,
• Muscle weakness and breathing difficulties
• Jaundice refers to an inflammation characterized by yellowed skin and eyes.
• A seizure (convulsions);
• Increased pressure in the skull can cause severe headaches, ringing ears, problems with vision, and pain behind your eye.

Side effects common to gemifloxacin include:

• Nausea, vomiting, stomach pain, diarrhea;
• Headache;
• Dizziness;

There may be other side effects.Need advice regarding side effects? For medical guidance on this matter, reach out to your physician.Report side effects by calling the FDA at 1-800-FDA-1088.

Warnings

Side effects of Gemifloxacin include tendon damage, nerve damage, and serious changes in mood, behavior, or emotions. If you experience any symptoms of headaches, nausea, vomiting, diarrhea, dizziness, anxiety, insomnia, difficulty concentrating, memory problems, thoughts of suicidal behavior, or pain in your joints, stop using the medicine immediately and contact your doctor. If you experience severe pain or discomfort in the chest, back, or stomach, seek emergency medical attention.

Before you take this drug

If you have an allergy to gemifloxacin (or other fluoroquinolones such as Ciprofloxacin or moxifloxacin), then do not take it. Gemifloxacin can cause swelling of or tear of a tendon (the fiber connecting bones and muscles within the body), especially the Achilles tendon in the heel. It can occur during the treatment or even several months later after stopping gemifloxacin. If you're over 60, take steroids, or have undergone a heart, kidney, or lung transplant, you may experience more tendon problems.

If you've ever:

• Tendon problems or arthritis; other joint disorders;
• Aneurysms, narrowing, or hardening of the arteries are all symptoms of blood circulation problems.
• Heart problems high blood pressure
• A genetic disorder such as marfan syndrome or ehlers-danlos syndrome;
• Diabetes;
• Myasthenia gravis (mg) is an autoimmune muscle or nerve condition.
• long qt syndrome
• Trouble swallowing pills
• Liver or kidney disease
• Epilepsy and other seizure disorders
• Low levels of potassium or magnesium in your blood.

This medicine is unknown to cause harm to an unborn child. Inform your doctor that you are expecting. While using the drug, you should not breastfeed. Anyone younger than the age of 18 is not allowed to use Gemifloxacin.

How to take Gemifloxacin?

Read all the instructions or guides that come with your medication and follow all the directions. Follow the directions on your prescription label. Drink extra water and take gemifloxacin while your kidneys are working. Take your medicine either with or without eating. Do not chew the tablet. Even if you feel better quickly, continue taking Gemifloxacin for its entire prescribed duration as skipping doses could result in resistance developing against it if taking Gemifloxacin does not treat viral infections such as colds and flus. This medicine should never be shared with another individual, even if their symptoms match those of this medicine. Keep away from heat, moisture, and light.

Details on dosage

Adult dose for bronchitis:
Orally, take 320 mg once daily for five days.
Comments:
as fluoroquinolones, including this drug, are associated with severe side effects. Since acute bacterial exacerbations cause chronic bronchitis, it is self-limiting in some patients. This drug should only be used to treat ABECB when there are no other treatment options.
Use: To treat ABECB caused by susceptible strains of Streptococcus pneumoniae, Haemophilus flu, H. parainfluenzae, or Moraxella catarrhalis.
Adult dose for pneumonia:
Orally, 320 mg once daily
The duration of treatment:
Due to infection with S pneumoniae (known or suspected), H influenzae (known or suspected), Mycoplasma pneumococcal, or Chlamydophila pneumococcal: 5 days
Due to a known or suspected infection with S. pneumoniae (MDRSP), Klebsiella pneumonia, or M. catarrhalis: 7 Days
Comments:
MDRSP isolates are defined as bacteria resistant to two or more antibacterials including penicillin with an in vitro minimum inhibitory concentration (MIC) of at least 2 micrograms/milliliter, second generation cephalosporins like cefuroxime, macrolides, tetracyclines or sulfamethoxazole-trimethoprim.
Use: To treat mild or moderate community-acquired pneumonia caused by susceptible isolates of S. pneumoniae, including MDRSP, H. influenzae, and M. catarrhalis.

What happens if I miss the dose?

If it is almost time for another dose, do not double up on this missed one and take both at the same time. Never more than one at any one time!

What happens if I overdose?

Call 1-800-222-1222 immediately if you suspect having consumed poison and need immediate medical advice or treatment.

What should be avoided?

Take gemifloxacin without dairy products like milk, yogurt, or calcium-fortified drinks. These products can be consumed as part of your regular diet, but not alone. These products could reduce the effectiveness of gemifloxacin. It is possible that antibiotics can lead to diarrhea. Warning signs for diarrhea could indicate an infection - call your physician immediately if watery or bloody diarrhea develops, as that could signal something more serious. Avoid sunbeds and tanning beds. Avoid tanning or sunlight. When you're outdoors, wear protective clothing and apply sunscreen with an SPF of 30 or more. If you experience severe sunburn, swelling, blistering, or rash after exposure to the sun, tell your doctor. You should avoid driving and other hazardous activities until you are sure of how gemifloxacin affects you. You may be unable to react.

Interaction with other drug

Taking gemifloxacin with certain medicines may make it less effective. Take your gemifloxacin 2 hours before or 3 hours after taking the medicine you are currently taking.

• Antacids containing magnesium or aluminum, such as Maalox or Rolaids, or ulcer medicines such as sucralfate or carafate;
• Didanosine powder (Videx), chewable tablets,
• Vitamin or mineral supplements containing aluminum, magnesium, zinc, and iron

Gemifloxacin may cause serious heart problems. You are at greater risk if you use other medications for asthma, diabetes, heart disease, high blood pressure, depression, mental illnesses, cancer, HIV, malaria, or HIV.

Tell your doctor of any medications, such as:

• Probenecid;
• A diuretic, or "water pills."
• Insulin or oral diabetes medication (check blood sugar levels regularly)
• A blood thinner—warfarin, Coumadin, or Jantoven
• Nsaids are non-steroidal anti-inflammatory medications. These include aspirin (Advil), ibuprofen, naproxen, celecoxib (Aleve), diclofenac (Indomethacin), indomethacin (Meloxicam), and many others.
• Steroid medicine—prednisone, methylprednisolone, and others.

The list below is not exhaustive. There are other drugs that may interact with gemifloxacin. These include prescription, over-the-counter, herbal, and other products. This medication guide does not list all interactions.