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[Generic name: Valrubicin the val-ROO-bi-sin]

Brand name: Dosage form: intravenous solution (40 mg/ml)
Drug class: antibiotics and antineoplastics

What is Valrubicin?

Valrubicin will treat bladder cancer, which hasn't spread to other areas of the body.

A majority of people do not respond completely to the hormone valrubicin. There is a chance that you'll require surgical intervention to eliminate your bladder in order to prevent the tumor from spreading to other parts of your body (spreading into other areas within the body).Valrubicin is also used for reasons not mentioned in this medication guide.

Side effects of Valrubicin

See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, like hives, trouble breathing, and swelling of your lips, face, and tongue,

Valrubicin may cause serious side effects. Consult your physician immediately in the event of:

  • The urine is stained with blood or a painful urination that lasts more than 24 hours;
  • Discomfort or burning sensation after you urinate,
  • Low white blood cell counts (about one week after the injection of valrubicin) low white blood cell counts (about 1 week after valrubicin injection) fever and mouth sores, sore throat, cough, difficulty breathing

HTML0 Common adverse effects of valrubicin could include:

  • Urine that is pink or red within the initial 24 hours following the time you received valrubicin
  • More frequent urge to urinate; leakage of urine;
  • Urination that is painful or difficult
  • Urinary pain;
  • An increase in urination after a night's sleep; more frequent urination during the night
  • Nausea and stomach pain.

This list does not encompass all possible side effects; others could occur as well. Please consult your healthcare provider should any adverse reactions occur, or report them directly to the FDA at 1-800-FDA-1088.


It is possible that you won't be able to fully respond to valrubicin, or your urinary tract might need to be removed surgically in order to stop your tumor from extending to other areas of your body.

Before you take this drug

You shouldn't be treated with valrubicin if you are sensitive to it or if you suffer from:

  • A urine tract infection;
  • Perforation of the bladder (a tear or hole)
  • Allergies to polyoxyl oil or other cancer medications (daunorubicin, doxorubicin, epirubicin, idarubicin, and mitoxantrone).

Inform your doctor if you have ever suffered from:

  • An overactive bladder, incontinence, or leakage
  • Bladder surgery;
  • Having trouble keeping a lot of the urine you're putting in there.

It could be more difficult for you to become pregnant when you're taking valrubicin. Still, you should utilize birth control to avoid pregnancies because the medicine could affect a newborn baby.

Valrubicin may harm an unborn child if the mother or father uses this medicine.

  • If you're female, do not use the medicine valrubicin if expecting. Make sure you use the most effective contraception to stop the birth of a baby while taking this medication and for a minimum of 6 months following the last dose.
  • If you're male, use effective birth control if you are a partner with someone who can get pregnant. Use birth control for at least three months following the last dose.
  • Contact your physician immediately when you notice a pregnancy when both the mother and father are taking the drug valrubicin.

Don't breastfeed while taking this medication, and at least two weeks follow the last dose.

How to take Valrubicin?

Valrubicin is delivered right into your bladder through an injection catheter placed in the urethra (the tube used to move urine from the bladder). Your doctor will prescribe you this medication, typically every week for 6 weeks.Valrubicin is typically administered in a solution weighing up to approximately 2.5 pounds (1/3 cup). The total amount is injected directly into the bladder. It is recommended to keep it in the bladder for two hours. Be sure to not use the bathroom during this period.

Inform your doctor if you struggle to hold the medication for 2 hours.If the medicine happens to get on your skin, clean it thoroughly using soap and warm water.You will require frequent urine tests. In addition, you might also need a urological biopsy or test of the bladder.Drink plenty of fluids after each time you take valrubicin.

There is a chance that you do not get an all-encompassing response to valrubicin. After 3 months of treatment, without any response, you could require surgery to remove This could help stop the cancer from spreading to different areas of your body. Metastatic bladder cancer is typically fatal.

Details on dosage

Usual Adult Dose for Urinary Tumor:

Normal adult dose: 800 mg taken intravenously every week for 6 weeks.
-Full the procedure at least two weeks following transurethral resection or the fulguration.
Patients should keep the medication for two hours prior to voiding it when they're capable of doing so. After two hours, patients should be able to avoid it.
Use: As an intravesical therapy for BCG-refractory cancer within the site (CIS) in the bladder of patients for whom a cystectomy could cause unacceptable morbidity or mortality.

What happens if I miss a dose?

Consult your physician for the appropriate treatment. If you do not make an appointment to receive your Valrubicin injection,

What happens if I overdose?

Since valrubicin can be administered by a medical expert in an environment that is medical, the risk of overdose is low, but it could cause worsening of bladder symptoms.

What should be avoided?

Follow the instructions of your physician regarding any limitations on foods, drinks, or activities.

Interaction with other drug

Because valrubicin doesn't get absorbed into the bloodstreamit is unlikely to be affected by any other medications you take. However, many medications can interact with each other. Inform your health care providers about the medications you take, including medications that are prescribed and available over the counter, vitamins, and herbal remedies.