What is Nafarelin Nasal?
Nafarelin nasal (for the nose) is used to treat central precocious puberty in girls and boys. Central precocious puberty refers to the early sexual development that takes place prior to 8 years old in girls or at 9 years old for boys and is characterized by bone development that is advancing in relation to the child's age. Nafarelin nasal can also be utilized to treat endometriosis in women who are over 18 years old. Nafarelin nasal is also employed for other purposes that are not covered in this guide to medication.
Side effects of Nafarelin Nasal
Contact emergency medical assistance. If you notice symptoms that are warning signs of an allergic reaction, such as the sensation of itching, rash, or chest pain; difficulty breathing; or swelling of your lips, face, and tongue.
Nafarelin nasal spray may cause serious side effects. If you suffer any of the following symptoms, contact your doctor right once:
- Vaginal spotting or continual menstrual bleeding.
- The pelvic area.
- A seizure.
- Depression—mood changes and feelings of self-worth devaluation losing interest in the things you loved, new sleep issues, and thoughts of harming yourself.
- An increase in pressure within the skull, causing severe headaches, ringing of your ears, dizziness, nausea, and vision issues or eye pain.
- Indications of a pituitary issue: sudden headache and blurred vision; vomiting; low pulse; slow breathing.
Certain children taking Nafarelin experience recent or more severe mental health issues. Contact your doctor immediately when your child is experiencing abnormal changes in their behavior or mood (anger or anxiety, crying, being irritable or restless).
Certain side effects may be anticipated during the first few months of taking Nafarelin nasal, but they should not be an indication to stop using the drug. Consult your physician if you experience any side effects that persist or are bothersome.
Common adverse effects of nafarelin nasal spray include:
- Vaginal bleeding, discharge, or dryness.
- Hot Flashes.
- The breast size.
- Runny nose.
- Headaches, muscle pain.
- Mood swings.
- Less interest in sex.
- Itchy, red, flaky, or itchy; the rash can be red, itchy, or flaky.
- An increase in body odor.
- Increase in pubic hair growth.
This is not a comprehensive list of possible side effects, and other side effects could occur. Consult your physician to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.
Do not take it if you're expecting. Use effective birth control and tell your doctor if you're pregnant. Certain children who take Nafarelin have had a change in their behavior or mental disorders. Consult your physician immediately in the event that your child experiences strange changes in the way they behave or mood (anger or crying, aggression, being agitated or restless). Nafarelin can also trigger seizures, particularly in those who have experienced a seizure, epilepsy, brain tumor, or blood vessel disorder inside the brain. The risk of having a seizure could also be greater if you use some antidepressant drugs. Nafarelin is not a good choice for nasal use if you experience abnormal vaginal bleeding that hasn't been examined by a physician.
Before you take this drug.
Nafarelin should not be used nasally if you have an allergy to nafarelin or other similar medications like goserelin, leuprolide, histrelin, or triptorelin.
If you're a female, you should not make use of Nafarelin nasal if you are:
- Abnormal vaginal bleeding that hasn't been examined by a doctor.
- If you are pregnant or lactating.
Speak to your doctor if you are ever diagnosed with:
- Epilepsy or another seizure disorder.
- Mental illness.
- A blood vessel or tumor in your brain.
- Polycystic ovarian disease.
- Low bone mineral density.
- Osteoporosis (in you or your loved one).
- If you smoke or drink a lot of alcohol.
Do not take Nafarelin nasal if you are expecting. It could harm the unborn baby. It is possible that you will need to take a pregnancy test that is negative prior to beginning this treatment. Although this medication may make you unable to ovulate or have regular menstrual cycles, you should use an effective nonhormonal birth control method to stop pregnancies while taking this medication. Nafarelin nasal may cause hormonal birth control to become less efficient, which includes birth control pills, injections, implants, skin patches, and vaginal rings. You can use barriers to birth control to avoid the pregnancy process: diaphragm, condom cervical cap, condom, as well as contraceptive sponge. It is not recommended to breastfeed when using Nafarelin nasal.
How to take nasal spray nafarelin?
The doctor will conduct tests to ensure that this medication is the best treatment for your child's illness. Follow the directions on the prescription label and review all medication guides and instructions. Your doctor may alter the dosage. Make sure you take the medication exactly as prescribed. Don't miss the doses you take of this medication. Dosing too much or not making use of nafarelin nasal in a proper manner could result in a hormonal imbalance, which may have undesirable adverse consequences.
Be sure to read and follow all instructions before using your nasal spray. Consult your physician or pharmacist if you don't comprehend these directions. Turn your head back slightly to spray the nose. Only use the amount of spray prescribed by your doctor and wait a minimum of 30 minutes between sprays. The doctor should examine your child's health through regular medical examinations, particularly during the initial six to eight weeks of using nasal nafarelin. Nafarelin may increase the production of certain hormones at the time of first taking this medication. It could make your child's signs of precocious puberty worse for a short period of time. Consult your doctor if the pubertal symptoms persist for longer than one month. If you experience regular menstrual cycles, you should notice them stopping when you're using nafarelin. Inform your doctor if your periods last for more than one month after the first time you started using this medication. Don't use Nafarelin nose spray for more than thirty days. The amount left in the bottle 30 days after usage will not be sufficient for a new full dose. Refill your prescription before the 30-day period expires to avoid running out of medication. Keep nafarelin nasal in an upright position at room temperature, far from heat, moisture, and light. Avoid freezing. Make sure the bottle is tightly sealed during times of no use.
Details on dosage
Usual Adult Dose for Endometriosis:
200 mg (as 1 spray into one nostril) by intranasal spray 2 times per day
Maximum dosage: 800 mg/day (as 1 spray in each nostril two times per day).
Time of treatment duration: 6 months.
Comments: Doubling the dose recommended should be considered for women who have menstrual issues for a period of 2 months following the start of treatment.
Treatment should be initiated between days 2 and 4 of the menstrual cycle.
Patients who are taking the dose recommended should have alternate nostrils. This includes the injection into one nostril in the morning and another in the evening.
Use: Treatment for endometriosis, which includes relief from pain and reduction of endometriotic lesions.
Usual Pediatric Dose for Precocious Puberty:
800 mg (as 2 sprays in each nostril) two times per day.
Maximum dose: 1800 mcg/day (as 3 sprays into alternating nostrils three times a day).
Comments: If patients are not able to achieve improvement in their symptoms within the first two months after treatment, gonadotropin compliance and independent sexual precocity must be evaluated. The dose can increase to 1200 mg/day in the event that both causes are eliminated.
The signs of puberty can occur during the early stages of treatment; however, they should disappear after one month.
Treatment can be continued until puberty resumption is at the right time.
Use: Treatment of central or gonadotropin-dependent precocious puberty.
What happens if I miss a dose?
Take the medication as quickly as you are able, but do not miss your missed dose if you are close to the time for the next dose. Do not take two doses at once. It is crucial not to miss NAFARELIN NARRAL.
What happens if I overdose?
Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.
What should be avoided?
Avoid sneezing or blowing out your nose right after applying the spray. This could make Nafarelin less efficient. Do not use any other nasal sprays within 2 hours of using Nafarelin. If you experience congestion in your nose, consult your physician before applying a nasal spray to treat congestion.
Interaction with other drugs
Discuss with your doctor any other medications you take, particularly:
- An antidepressant.
- Seizure medicine.
- Steroid medicine.
This list isn't complete. Other medications may interact with nasal nafarelin, such as medications that are prescribed and available over the counter, vitamins, and herbal products. There are many possible interactions between drugs that are listed here.