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Raloxifene

Generic Name: Raloxifene [ra-LOX i-feen]
The Brand Name is Evista.
Dosage Format: Oral tablet (60 mg)
Drug Classes: Hormones, antineoplastics, selective estrogen receptor modulators

What is Raloxifene?

Raloxifene helps treat osteoporosis among postmenopausal females.Raloxifene does not have a place suitable for male usage.Raloxifene can also be used to treat conditions not covered in this medication guide.

Side effects of Raloxifene

See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, such as difficulty breathing, hives, and swelling of your lips, face, and tongue,

Raloxifene may cause serious side effects. Stop using raloxifene and call your physician immediately in the event that you experience:

  • Swelling, tenderness, or any other changes that occur in your breasts;
  • Symptoms of a stroke—sudden weakness or numbness (especially for one leg) or slurred speech or vision problems
  • Indications for a blood clot inside the lung: chest pain, trouble breathing, coughing up blood,
  • Indications of a blood clot deep within the body: swelling and warmth, or redness in the arm or leg.

Common negative side effects of raloxifene include:

  • Hot Flashes;
  • Leg cramps;
  • Swelling in your feet, hands, or ankles;
  • Joint pain;
  • Flu symptoms,
  • More sweating.

There isn't an exhaustive description of the various adverse results. There are other effects that could occur. Consult your physician for medical advice about adverse effects. If you have any concerns, report them to the FDA by calling 1-800-FDA-1088.

Warnings

Raloxifene can increase the chance of developing bleeding from your lungs, your leg, or even the eye. You should not take raloxifene if you've previously experienced this type of blood clot.

Raloxifene may also increase the risk of having a stroke, which could lead to death. The risk is greatest in the case of certain risks (such as smoking, suffering from heart problems, excessive blood pressure, or having previously experienced a heart attack or stroke).

Although this medication is designed to be used only by postmenopausal women, you shouldn't take raloxifene if you are pregnant or nursing.

Before you Take this Drug

This medicine can increase the chance of developing blood clots in your lung, leg, or even eyes. You should not use raloxifene when you've suffered from this kind of blood clot.

This medicine is to be used only by women who are unable to bear a baby anymore. Raloxifene could harm an unborn baby. Do not use it if you are expecting or may be pregnant.

Avoid breastfeeding when using raloxifene.

Raloxifene increases the risk of suffering a stroke, which could cause death. Inform your doctor that you've had:

  • Heart problems, irregular heartbeats,
  • A stroke or heart attack, which includes "mini-strokes";
  • High blood pressure
  • Cancer
  • If you smoke.

Inform your doctor if you have ever suffered from:

  • A blood clot;
  • Triglycerides that are high result from the use of estrogen.
  • Kidney or liver disease
  • Endometriosis;
  • Abnormal vaginal bleeding
  • If you're not going through menopausal symptoms.

How to Take Raloxifene?

Follow all instructions on the label of your prescription and read the medication guide or instructions sheets. Follow the medication precisely as directed.

Use the medicine daily at the same time every day, whether with or without eating.

If you are undergoing major surgery or have been in bed for a long time, you must quit taking raloxifene a minimum of 3 days before the date. You might not be able to resume the medication until you're back in active mode. Be sure to inform any doctor or surgeon who treats you that you are taking raloxifene.

Raloxifene is just one component of a full programme of treatment, which could also include changes in diet and exercise as well as bone mineral density testing and taking vitamin D and calcium supplements. Follow the instructions of your physician precisely.

Your doctor should be able to check your health regularly. Examine the breasts to detect lumps and bumps on a regular basis, and undergo regular mammograms.

Place it in a cool, dry place far from heat and moisture.

Details on Dosage

Usual Adult Dose for Osteoporosis:

60 mg taken orally daily
Comments:
For treatment as well as to prevent osteoporosis, patients should be advised to supplement their diet with supplements of vitamin D if their daily intake is insufficient.
When this medication is utilized to decrease the risk of developing breast cancer, The optimal time of treatment isn't yet known.
Uses:
Prevention and treatment of osteoporosis for postmenopausal females
Reduced risk of developing breast cancer that is invasive in postmenopausal females with osteoporosis or who are at a high risk of breast cancer that is invasive.

Usual Adult Dose for Prevention of Osteoporosis:

60 mg oral per day
Comments:
For treatment or prevention of osteoporosis, patients should include calcium supplements or vitamin D if their daily intake is not sufficient.
When this medication is utilized to decrease the risk of developing invasive breast cancer, the ideal time for treatment isn't established.
Uses:
Treatment and prevention of osteoporosis among postmenopausal women
Reduction in the risk of breast cancer that is invasive for postmenopausal women suffering from osteoporosis or at high risk of developing invasive breast cancer.

Usual Adult Dose for Prevention of Breast Cancer:

60 mg taken orally daily
Comments:
For treatment or prevention of osteoporosis, patients should supplement their diet with calcium and vitamin D if their daily intake is insufficient.
If this drug is employed to decrease the chance of developing invasive breast cancer, the optimal time for treatment isn't yet known.
Uses:
Treatment and prevention of osteoporosis among postmenopausal women
Reduction in the risk of invasive breast cancer among postmenopausal women who suffer from osteoporosis or who are at a high risk of developing invasive breast cancer.

What Happens If I Miss a Dose?

It is recommended to take the medicine in the shortest time possible. However, avoid your missed dose if you are close to the time of the next dose. Don't take two doses at a time.

Make sure you refill your prescription before the expiration date of your medication.

What Happens If I Overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What Should be Avoided?

If you are taking calcium supplements, make sure you don't exceed the amount your physician has advised. Doing more calcium than is recommended is not going to provide additional protection to your bones and could result in serious adverse effects, including kidney stones.

Do not sit for prolonged periods of time when taking raloxifene.

Interaction with Other Drugs

Discuss with your doctor any other medications you take, including:

  • Cholestyramine;
  • Warfarin (Coumadin, Jantoven);
  • Birth medication for control as well as hormone replacement therapy.

This list isn't complete. Other drugs can interact with raloxifene, including prescription and over-the-counter medicines, vitamins, and herbal products. There are many possible interactions between drugs. are included here.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

CSA Schedule*

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