The Web Health



Generic Name: Ibandronate (oral/injection) [eye-BAN-dro-nate].
Drug Class: Bisphosphonates.

What is Boniva?

Boniva is a bisphosphonate-based medicine that alters the formation of bone and breaks them down in the body. It can reduce bone loss and help prevent bone fractures from occurring.

Boniva is a prescription medicine that is used to treat and stop osteoporosis among women following menopause. Ibandronate increases bone mass and reduces the likelihood of having an injury to the spinal column.It isn't known for how long Boniva can be used for the treatment or reduction of osteoporosis. It is recommended that you see your doctor often to see whether this medication is appropriate for you.


It is not recommended to use Boniva. If you suffer from serious kidney disease or low levels of calcium in your blood.Don't use a tablet if you have issues with your esophagus or if you are unable to stand up straight or sit down for more than 60 minutes before taking the tablet.

Boniva tablets may cause serious health issues in the stomach or esophagus. Do not take Boniva and contact your doctor immediately if you experience chest pain, worsening heartburn, or discomfort when swallowing.Contact your doctor if you experience muscle spasms, numbness, or sensations of tingling (in your feet, hands, or around your mouth), new and unusual pain in your hips, or severe joint pain in your muscles, bones, or joints.

Side effects of Boniva

See a doctor immediately. Get medical attention immediately if you notice symptoms that indicate an allergy reaction. Boniva:difficulties; hives; wheezing; breathing difficulties and swelling of your lips, face, and tongue.

Stop taking this medicine and contact your doctor immediately if you suffer from:

  • Chest pain, or heartburn that is new or getting worse.
  • Difficulties or pain while swallowing.
  • Burning or pain under your ribs or on the lower back.
  • Extreme heartburn, burning pain in your stomach's upper part, or the coughing up of blood.
  • A new or uncharacteristic pain is felt in your hip or thigh.
  • Numbness, pain, or swelling in the jaw.
  • Severe joint, bone, or muscular pain.
  • Low levels of calcium,muscle muscles spasms or contractions, numbness, or sensation (around your mouth or on your toes and fingers).

Common Boniva side effects can be:

  • Heartburn, stomach pain, diarrhea.
  • Back bone pain, back joint or muscle pain.
  • Discomfort in your arms or legs.
  • Headaches migraine.
  • Fever, chills, tiredness, and flu-like symptoms.

This isn't a complete list of possible side effects, and other effects may also be present. reach your doctor regarding any adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Before you take this drug

Don't take Boniva. If you have an allergy to ibandronate or are suffering from

  • Severe kidney disease severe kidney disease
  • Low levels of calcium in the blood (hypocalcemia).

Don't take a Boniva tablet. If you are experiencing issues with your esophagus or if it is difficult to stand up straight or sit for more than 60 minutes, Ibandronate could cause serious issues with the stomach or esophagus. It is important to remain standing for a minimum of 1 full hour following taking this medication.

To ensure this medication is suitable for you, inform your doctor if you have any of the following:

  • Trouble swallowing.
  • Issues with your stomach or digestion.
  • Hypocalcemia.
  • A dental issue (you may require a dental exam before using Boniva).
  • kidney disease.
  • Any medical condition that makes it difficult for your body to take in the nutrients in foods (malabsorption).

In rare instances, it can lead to osteoporosis (osteonecrosis) within the jaw. The symptoms include jaw pain, swelling, red gums, loose teeth, or slow healing following dental treatment. The longer you are using Boniva, the more likely you are to get this disease.

The jaw bone may be prone to osteonecrosis. It could be more likely if you've had cancer or have received radiation, chemotherapy, or steroids. Other risk factors are blood clotting issues, anemia (low red blood cells), and a present dental issue. Consult your physician about the risks and benefits of taking this medication. It isn't known if ibandronate can harm a newborn baby. Notify your doctor if you are pregnant or intend to get pregnant.

It's not clear if ibandronate is absorbed into breast milk or if it harms the nursing infant. If you are breastfeeding a child, notify your doctor.

How to take Boniva?

Utilize Boniva exactly as directed by your physician. Follow the directions on the prescription label. Do not take this medicine in greater or lesser quantities or for longer periods than prescribed. The tablets are consumed every month, at least once. The injection is given through an IV every three months. Tablets can be taken at home; however, an experienced healthcare professional is required to administer the injection.

Start taking the tablet in the morning for at least 60 minutes prior to eating, drinking, or taking any other medication. The medicine should be taken every day of the month, but always first thing in the morning. Consume this tablet by sipping a whole glass (6 to 8 ounces) of plain water. Avoid drinking tea, coffee, soda, juice, and mineral water. Do not consume anything other than plain water. Don't crush, chew, or chew on a tablet. Swallow it whole.

At least 60 minutes (1 hour) after using tablets:

  • Do not recline or lie down.
  • Avoid taking any additional medications like calcium, vitamins, or analogues.

Be sure to focus on your dental hygiene when using Boniva. Make sure to floss and clean your teeth on a regular basis. If you are going to need any dental procedure (especially surgery), inform your dentist beforehand that you're using this medication. Boniva is just one component of a comprehensive treatment plan that could include dietary changes, exercises, bone mineral density testing, and vitamin and calcium supplements. Follow your doctor's advice carefully.

Place it in a cool, dry place free of heat and moisture. Your doctor will decide the length of time you will be treated with this medicine. Ibandronate is usually prescribed for 3 to 5 years.

Details on dosage

Usual Adult Dose for Osteoporosis:

Oral: 150 mg orally, once a month on the same date each month.
IV Injection: 3 mg via IV injection for 15–30 seconds at least every three months.
Comments: The IV injection shouldn't be administered more often than once every 3 months.
Take serum creatinine prior to every injection.
Perform a routine oral exam prior to administering IV injections.
Uses: Treatment and prevention of osteoporosis postmenopausal for better bone mineral density (BMD) and reducing the chance of vertebral fractures

Usual Adult Dose for Prevention of Osteoporosis:

Oral: 150 mg taken orally every month on the same day.
IV Injection: 3 mg administered via injection for 15–30 seconds each month.
Comments: IV injections should not be administered more often than every 3 months.
Take serum creatinine before every injection.
Perform a routine oral examination prior to the administration of IV injections.
Uses: Treatment and prevention of osteoporosis postmenopausal for better bone mineral density (BMD) and to decrease the chance of vertebral fractures

What happens if I miss a dose?

Tablets of Boniva: If, for some reason, you do not remember to take your tablet in the first hour of the morning, on your schedule, don't do it until later on in the morning. Then wait until the following morning to take the dose you missed. You can then resume your regular monthly schedule on the selected dosage day. If the next dosage is a little less than seven days away, you should wait until the time is right and not miss the dose that was missed. Don't have two (2) doses in a week. The Boniva Injections Contact your physician to get instructions if you don't make an appointment for the injection.

What happens if I overdose?

for Boniva tablets: Drink a full glass of milk and seek urgent medical attention, or contact the Poison Help line at 1-800-222-1222. Do not force yourself to throw up, and don't lay down.

Because the injections are administered by a health expert in a medical setting, it is highly unlikely for an overdose to occur.

What should be avoided

Do not take any other medications within 60 minutes after taking Boniva. This includes calcium, vitamins, and antacids. Certain medications can hinder the body's ability to absorb ibandronate. Try not to smoke or to stop. Smoking cigarettes can decrease your bones mineral content, which increases the possibility of fractures. Beware of drinking excessive amounts of alcohol. Drinking heavily can result in bone loss.

Interaction with other drugs

Discuss with your physician all your medications currently in use and all you are about to start or stop using, in particular:

  • Aspirin is a common ingredient.
  • The NSAIDs (nonsteroidal anti-inflammatory medicines) are ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac (also known as indomethacin), diclofenac, and more.

This list isn't comprehensive. Other medications may be incompatible with ibandronate, such as prescription and over-the-counter medicines as well as vitamins and herbal supplements. There are not all the interactions mentioned in this drug guide. Consult your doctor regarding the most effective dosage schedule for the other medicines you take.



Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories