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Generic Name: of Atropine and Pralidoxime [AT-roe-peen and PRALIDOX-eem]
Brand names:
ATNAA or DuoDote
Drug class: antidotes

What is ATNAA?

ATNAA is a combination medication employed as an antidote in treating poisoning from pesticides (insect spray) or chemicals that disrupt the nervous system's central part, for example, nerve gas.ATNAA is not as effective an antidote against all kinds of poisoning caused by pesticides. It is possible that you will require medication or other treatments.ATNAA is also employed for reasons not mentioned in this guideline for medication.

Side effects of ATNAA

Contact a medical professional immediately in the event that you exhibit symptoms that indicate an allergy, such as symptoms of hives, breathing difficulties, and swelling of your lips, face, and tongue.A few of the adverse consequences of atropine and pralidoxime could be similar to symptoms of poisoning. Your healthcare providers will be watching closely to see if you are responding properly to the medication or if you're suffering from any serious adverse side effects.

Inform your carers immediately. If you suffer from:

  • Are You Feeling Chest Pummel or Flutter
  • Chest pain, which is spreading into your shoulder or jaw;
  • Trouble swallowing
  • Uncomfortable or difficult to urinate;
  • Minimal or no urination
  • Sudden shifts in mood or behaviour unusual changes in mood or behaviour
  • Blurred vision blurred vision, pain, or seeing halos of light.

The risk of side effects is more prevalent in older adults.

Common adverse consequences of ATNAA could include:

  • Breathing problems;
  • Dry mouth;
  • Dry eyes, changes in vision, and increased sensitivity to light
  • Nausea, vomiting;
  • High heart rate, increased blood pressure
  • Changes in behaviour, such as feeling either confused or excited;
  • Reduced urination
  • Headache, dizziness, drowsiness;
  • Muscles weak;
  • Itchy skin pimples;
  • Abnormal tests of liver function.

These may not be all of the possible side effects, and other may occur as well. Please consult a healthcare provider regarding possible adverse reactions of this medication.You can report any adverse reactions to the FDA at 1-800-FDA-1088.


In the event of an emergency, it is possible that you won't be able to inform doctors about your health concerns. It is important that the doctor who cares for you afterwards knows that you've received ATNAA.

Prior to using this drug

If you can, prior to the time you take ATNAA, tell your doctor if you've previously had:

  • An allergy to or sensitivity to medication
  • Heart conditions or heart problems, stroke as well as a stroke;
  • High blood pressure;
  • Kidney or liver disease
  • Asthma, COPD (chronic obstruction pulmonary disorder), or any other breathing problems;
  • Glaucoma;
  • Urination issues.

In an emergency situation, it might not be feasible to notify your carers that you are nursing or pregnant. It is important that the doctor caring for your baby or your pregnant mother be aware that you've taken this medication.

How do I take ?

ATNAA is injectable into a muscle located in the upper thigh. Your healthcare professional will provide the injection.ATNAA is typically administered at the earliest possible time following the onset of poisoning symptoms. If you are still experiencing symptoms after 10 to 15 minutes, the patient will be given two additional injections.Your blood pressure, breathing and kidney function, oxygen levels, and many other vital indicators are closely watched.You could be monitored throughout the course of up to 72 hours in order to confirm that the treatment is working and that you aren't suffering any negative effects from the poison.

What happens if I miss the dose?

Because ATNAA is only used as required, it doesn't need to be part of a daily dosage schedule.

What happens if I overdose?

Since the medication is prescribed by a medical expert in a medical environment, the risk of overdose is less likely to occur.The risk of overdose is higher if you take ATNAA but haven't had any exposure to the specific poisons this drug is intended to treat. Some symptoms include eye problems or a feeling of instability, loss of balance or coordination issues, difficulty concentrating, a rapid heart rate as well as hallucinations, confusion (seeing or hearing sounds), decreased sweating, dry and hot skin, fainting or weak breath, or a stop in breathing.

Aviod this

Beware of becoming dehydrated or overheated during workouts and in hot temperatures. Atropine is a stimulant that can reduce sweating. You might be more susceptible to suffering from heat stroke for a brief period following your treatment.

Interaction with other drug

Other medications may interact with ATNAA. Other medications can affect ATNAA, such as medications that are prescribed and available over the counter, vitamins, and herbal products. If you can, prior to getting ATNAA, talk to your physician about all of the medications you currently take.