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Name of the Generic: Bicalutamide Nbye-ka-LOO-ta-mide.
Name of the Brand: Casodex.
Dosage Format: Oral tablet (50 mg).
Drug Classes: Antiandrogens, hormones, and antineoplastics.

What is bicalutamide?

Bicalutamide Bicalutamide is a prescription drug that is part of the class of drugs known as orrogen receptor antagonists that are non-steroidal. Bicalutamide is a treatment for prostate cancer that has spread to other areas of the body (metastatic). Bicalutamide is administered in conjunction with a different medicine known as a one-time luteinizing (LOO-tee-in-ize-ing) hormone-releasing hormone, or LHRH. LHRH aids in stopping the testicles from releasing testosterone. It isn't known whether bicalutamide tablets have been proven safe or effective for children.


Bicalutamide may cause harm to a baby born in the event that you father an unborn child while taking this medication. Use effective birth control methods to avoid pregnancy while taking bicalutamide for at least 130 days (about 19 weeks) following your last dose.

Before you take this drug

You shouldn't make use of this medicine if you are sensitive to bicalutamide. Utilize effective birth control if your sex partner is likely to become pregnant. Bicalutamide may cause harm to an unborn baby if you have a child while taking this medication. Keep using birth control for at least 130 days (about 19 weeks) after the last dose. Bicalutamide is not suitable for use by children or women. This medicine could cause birth defects if a woman takes it during pregnancy. To ensure that this medication is suitable for you, inform your physician if you have any of the following:

  • Liver disease.
  • Diabetes.

How to take bicalutamide?

Use bicalutamide according to the prescription given by your physician. Follow all instructions on the prescription label and study the entire medication guide or instruction sheet. Your doctor may modify your dosage. Bicalutamide is typically taken once each day, either during the day or in the evening. The medicine should be taken every day, either with or without meals. LHRH is injected in the form of an injection or a tiny implant that is injected with an injection needle around the navel. LHRH injections are administered regularly, for example, every 4 weeks. Follow the instructions of your doctor. You shouldn't stop using bicalutamide until your doctor instructs you to. You'll need to take regular medical examinations. Keep at room temperature, free of heat and moisture.

Details on dosage

Usual Adult Dose for Prostate Cancer:

Together, in combination with LHRH analog 50 mg, orally, once every day (morning or at night).
Comments: Therapy with this drug must be initiated simultaneously with treatment with the LHRH analog.
If a dose is not taken, Take another dose within the planned time. Don't miss the dose, and don't double the dose to take the next one.
Use: In combination with treatment with a luteinizing hormone-releasing hormone (LHRH) analog to treat stage D2 metastatic cancer of the prostate.

What happens if I miss a dose?

Don't miss the dose you missed, and take your next dose at the normal time. Avoid taking two doses at the same time. Consult your physician for the appropriate treatment in the event that you don't make an appointment to receive the LHRH injection.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.

What should be avoided?

Avoid driving and other hazardous activities until you understand the effects of this medication on your body. Your reaction could be affected. Bicalutamide can make you more susceptible to sunburn. Avoid tanning beds or sunlight. Be sure to wear protective attire and sunblock (SPF 30 or greater) while you're outdoors.

Side effects of Bicalutamide

See a doctor immediately. If you are experiencing symptoms that indicate you are experiencing an allergic reaction due to the bicalutamide, such as hives, breathing problems, or swelling of your lips, face, and tongue, Contact your doctor immediately. If you are suffering from:

  • The breasts, swelling, or pain.
  • Suddenly chest pain with wheezing, a dry cough, and feeling exhausted.
  • Low red blood cells (anemia): pale skin, unusual fatigue, feeling lightheaded or sluggish, cold feet and hands.
  • Liver issues The symptoms include nausea and stomach pain, fatigue, feeling tired, nausea, and a loss of appetite. black stools, dark urine, jaundice (yellowing of the eyes or skin), chills, fever. Blood sugar levels are high. more thirst, increased urination rate, dry mouth, odor of fruity breath.
  • If you also (if you also take warfarin) are bleeding or bleeding.

Common side effects of bicalutamide include:

  • Anemia.
  • Urine with blood;
  • Fever, chills, flu-like symptoms.
  • Trouble breathing, hot Flashes.
  • The pelvis, back, or stomach.
  • Swelling in your ankles, arms, or feet; swelling in your legs, arms, or ankles.
  • An increase in night-time urination.
  • Weakness, dizziness.
  • Nausea, diarrhea, and constipation.

This is not a comprehensive list of possible side effects, and others could happen. Consult your physician for advice regarding medical effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Inform your doctor about all other medications, including:

  • A blood thinner (warfarin, coumadin, or Jantoven).

This list isn't complete. Other drugs can interact with bicalutamide, such as prescription and over-the-counter medicines, vitamins, and herbal products. There are many possible interactions between drugs, which are listed here.



Prescription only

Pregnancy & Lactation

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