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Aclidinium and formoterol

Generic name: aclidinium and formoterol [a-kli-din-ee-um-and-for-moe-ter-ol]
The brand name is duaklir pressair.
Dosage in the form of inhalation powder (400 12 mcg/12 mcg/inh)
Drug class: bronchodilator combinations

What are Aclidinium and Formoterol?

Aclidinium and formoterol are a combination medication used to stop the obstruction of airflow as well as decrease flare-ups among adults suffering from COPD (chronic obstructive pulmonary disease), which includes bronchitis as well as emphysema.

Aclidinium as well as formoterol are intended for COPD sufferers and are not recommended for treating asthma.

Aclidinium and formoterol could also be utilized for other purposes that are not covered in the guide.


Aclidinium as well as formoterol are intended for people who suffer from chronic obstructive pulmonary disorder (COPD) and shouldn't be utilised for treating asthma.

Aclidinium isn't recommended for use with formoterol if you are intolerant to formoterol or aclidinium or have an extreme allergic reaction to milk protein.

Aclidinium and formoterol are not the best medicines to use as a last resort. It is not fast enough to stop an acute bronchospasm.

Consult a doctor in the event that your breathing difficulties don't improve or if symptoms become more severe.

Before You Take This Drug

This medicine is for you if your body is allergic to formoterol or aclidinium or if you have a severe reaction to milk protein.

Inform your physician if you were ever diagnosed with:

  • Heart disease, high blood pressure;

  • A seizure

  • Glaucoma

  • Diabetes

  • Thyroid disease

  • An increased prostate or problems with urination

Consult your doctor if you are breastfeeding or pregnant.

Aclidinium and formoterol are not recommended for use by people less than 18 years of age.

How to take aclidinium and formoterol?

Make sure you follow the instructions on your prescription label. Also, go through all the medication guides. Follow the medication exactly as prescribed.

Aclidinium, formoterol, and other medications are not cures for attacks of bronchospasm


Use only fast-acting inhalation medicines for attacks. Get medical help if breathing issues get worse rapidly and you feel the medications you are taking aren't effective enough.

Take note of and follow the instructions for use that come with your medication. Consult your physician or pharmacist if you don't understand these directions.

Keep the product at room temperature, far from heat, moisture, or sunlight. Avoid storing aclidinium or formoterol on a surface that is vibrating. Keep the inhaler device inside the bag until it is ready to be taken out.

Toss the inhaler out two months after having opened the bag, when the indicator for dose displays a zero, or if the inhaler appears completely empty and is locked out (whichever is first).

It is not advisable to stop taking aclidinium or formoterol in a hurry. A sudden stop can increase the severity of your illness.

Details on Dosage 

Usual adult dose for chronic obstructive pulmonary disease—maintenance:

Inhale once twice a day (morning and at night)

maximum dose: 2 inhalations per day.

What Happens if I Miss a Dose?

Don't miss the missed dose; then take the next dose according to the normal timing. Avoid using more than two doses in one go. Use no more than one inhalation twice during a 24-hour time period.

What Happens if I Overdose?

Get medical assistance in an emergency or dial toll-free the poison helpline at 1-800-222-1222.

Some of the symptoms associated with an overdose are dry mouth, blurred vision, nausea, muscle spasms, headaches, tremors, and fast or rapid heartbeats. 

What Should be Avoided?

Avoid using a third inhalation bronchodilator containing formoterol, arformoterol, indacaterol, olodaterol, salmeterol, or formoterol.

Side effects of Aclidinium and Formoterol

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as difficulty breathing, hives, and swelling of the lips, face, and tongue.

Mild effects

  • Wheezing, wheezing, or breathing difficulties following the use of this medication;

  • Aggravation of breathing problems

  • Tremors, nervousness, chest pain, fast or pounding heartbeats,

  • Extreme migraine that is pounding your ears or neck;

  • Urination that is painful or hard to perform, or having to urinate more frequently;

  • Tunnel vision and blurry vision redness or eye pain, and seeing halos of the lights

  • high blood

    sugar (increased urine or thirst, hunger, dry mouth, or breath that smells of fruit) as well as

  • Low potassium level: leg muscle cramps, constipation, unsteady heartbeats, the feeling of fluttering inside your chest, pain or tingling, or a feeling of limpness

Adverse side effects

  • Headache

  • Back hurt

  • Cold symptoms like congestion, coughing, and a sore throat.

It's not a complete listing of all side effects. Other side effects could occur. Consult your physician to seek medical advice on the negative effects. The best way to report adverse reactions is to call the FDA at 1-800-fda-1088.

Interaction with other Drugs

Discuss with your physician the other medicines you are taking, particularly:

  • Atropine;

  • Antifungal or antiviral medication;

  • Monoamine oxidase inhibitors, tricyclic antidepressants, and other drugs that extend the qt interval

  • Beta-blockers;

  • Medications for treating depression, anxiety, and mood disorders. Mental illnesses;

  • Cold or allergy medication (Benadryl and other brands);

  • Medicines used to treat the symptoms of Parkinson's disease;

  • Medicine to treat stomach disorders, motion sickness, and ibs;

  • Medicines for treating the overactive bladder medicine to treat an overactive bladder

  • A different bronchodilator medicine.