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Name of the generic: permethrin topical topical per-meth-rin per-meth-rin
Brand names: Acticin, Lice Bedding Spray, Nix Complete Lice Treatment, Nix Complete Lice Treatment System, Nix Cream Rinse, etc. List the 10 names.
Class of drugs: topical anti-infective

What is Acticin?

  • Permethrin is a medication to combat parasites.

  • Acticin (for the skin) can be used to treat head lice as well as scabies.

It is also possible to use Acticin in other ways not mentioned in this guideline for medication.


Be sure to follow all the directions printed on the label of your medication and on the label of your package. Inform your healthcare providers about any medical issues or allergies, as well as all medications you are taking.

Before you Take this Drug

It is not recommended to use Acticin if you are allergic to permethrin or chrysanthemum.

Speak with a physician or pharmacist to determine if it's safe for you to take this drug if you are suffering from any other medical issues.

Acticin should not be thought to cause harm to the unborn child. Consult your doctor if you are planning to have a baby.

It's not clear if topical permethrin is absorbed into breast milk or whether it can harm the nursing infant. Do not breastfeed while taking this medication.

Acticin is not recommended for children who are less than two months old.

How to take Acticin?

Take it exactly as indicated on the label or as directed by your physician. Avoid using in higher quantities, in smaller quantities, or for more than is recommended.

It is possible to experience a temporary increase in swelling, itching, and redness in the skin after you use Acticin.

Don't take it with food. This medication is intended for use solely on the skin. Avoid applying the medicine to open wounds or cuts. If the medication is absorbed into your mouth or eyes, rinse it out with clean water. Use the surface spray on surfaces that are used in the home and not directly on your skin.

There is a possibility that you will have to shake the medicine each time you use it. Be sure to follow the instructions on the label of the medication.

What happens if I miss a dose?

Because Acticin is typically only needed once, you're likely not on an adherence schedule. It is recommended to wait for at least 7 days prior to attempting a second application.

What happens if I overdose?

You should seek medical attention immediately. Contact the poison help line at 1-800-222-1222. If you suspect you've consumed too much of the medication or if you suspect someone else has taken the medicine.

To treat scabies:

  • Dry and clean the skin. Apply a small amount of the medicine to every body part, from the neck to the soles of the feet. Massage it in thoroughly. Apply the cream to the skin for between 8 and 14 hours. Then rinse it completely.

  • When you use Acticin for infants, apply the medication to the temples, scalp, and forehead. Do not apply it near the lips, eyes, nose, or genitals.

  • If the problem does not improve in 14 days, you can apply Acticin once more.

What should be avoided when taking Acticin?

Cleanse your eyes using water in case Acticin occurs in the eyes.

Scabies and lice infections are extremely infectious. Do not share intimate or sexual contact with other people until the lice or scabies disease has gone away. Do not share your hairbrushes, combs, and accessories for hair, hats, clothes, bed sheets, or any other personal items you use.

Do not use other medicines to treat the area you are treating with Acticin unless your physician recommends it.

Treatment of head lice:

  • Shampoo your hair exclusively (no conditioner or 2-in-1 hair products). Rinse thoroughly, then towel dry your hair. Do not leave the hair dry.

  • Keep your eyes protected with an eye-protection towel or washcloth. Make sure to cover all your hair. Let it sit for about 10 minutes. After that, rinse it off with warm water.

  • It is also possible to use a nit comb to get rid of lice eggs from your hair. The hair must be damp when using the nit comb. Use only one area of hair at a time, using a comb that can handle 1 to 2 inches of hair all the way from the scalp up to the end.

  • Rinse your nit comb regularly throughout use. Remove the nuts from a plastic bag, then throw it in the garbage.

  • Make sure to check the scalp every day to ensure that all the nits have been eliminated.

  • If you continue to see lice seven days after your initial treatment, you can apply another treatment.

For treatment of the symptoms of pubic lice (crabs):

  • Every sexual partner must be treated with respect.

  • Dry and wash the treatment region. Apply Acticin on the pubic hair as well as any other hairs around the thighs and within the anus (avoid places inside the vagina and rectum).

  • Then leave the medication on for approximately 10 minutes. After that, work it into a foam, then rinse with hot water.

  • It is also possible to use a nit-comber to eliminate lice eggs from pubic hair (the hair must be damp).

In order to prevent the spread of infection to prevent reinfection, clean all clothes and hats. To prevent reinfection, wash all bed sheets, bedding, and bath towels in hot water. Dry them with high temperatures. Dry-clean all clothing that is not washable. Wash all hair brushes, combings, hair brushes, and accessories in warm water for a minimum of 10 minutes.

Spray the surface of your house with permethrin to clean non-washable objects, for example:

  • Furniture;

  • Mattresses and pillows

  • Toys for stuffed animals;

  • Hats, gloves, and scarves

  • Either headbands or headphones.

  • The interior of a bike helmet, or

  • Carpets and seats in the interior of your vehicle.

The pillows or toys that cannot be cleaned are best kept sealed in airtight plastic bags for up to 4 weeks. When you remove the bag, thoroughly shake the product outside.

Clean all carpets, rugs, and carseats. Throw your vacuum cleaner bags away.

In order to get the most thorough treatment for scabies or lice, you must take care of your surroundings (clothing or bedding) while you are treating your hair and/or your body.

Place Acticin in a refrigerator at room temperature, far from heat and humidity. 

Side effects of Acticin

Contact a medical professional immediately. Get medical attention immediately if you notice

warning signs of an allergic response, such as symptoms of hives, difficulty breathing, or swelling on your lips, face, or tongue.

Consult your doctor immediately if you are experiencing intense burning, stinging swelling, or redness following the application of Acticin.

Mild effects

  • Minor burning, stinging burning, or just a slight, mild rash;

  • Numbness or tingling wherever the drug was applied

  • Headache,

  • dizziness;

  • Fever

  • Stomach pain, nausea, vomiting, and diarrhoea.

It isn't a comprehensive list of possible side effects, and there are other possible side effects. Consult your physician to seek medical advice on adverse consequences. It is possible to report any side effects to the fda by calling 1-800-fda-1088

Interaction with other drugs.

There is no way to know if any other medications you consume by mouth or inject will have any effect on the topically applied Acticin. However, many medications can interact with each other. Be sure to inform your medical professionals about any medications you are taking, such as prescription or over-the-counter drugs, vitamins, and herbs.