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Zavesca

Name of the generic: miglustat mi-GLOO-stat mi-GLOO-stat [ mi-GLOO-stat
Drug class: Miscellaneous metabolic agents

What is Zavesca?

Zavesca decreases the production of a specific protein within the body of people suffering from type 1 Gaucher's disease.

Gaucher's disease can be described as a genetic illness where the body is deficient in the enzyme that is needed for breaking down specific fat substances (lipids). Lipids build up within the body, leading to symptoms like bleeding or bruising that is easy to stop, as well as anemia, weakness, bone or joint pain, an enlarged spleen or liver, or weak and easily broken bones.

Zavesca is used to treat mild to moderate Gaucher disease in those who are unable to receive enzyme replacement therapy.Zavesca can improve the condition of the spleen, liver bones, liver, and blood cells of people suffering from Gaucher's disease type I. It is, however, not a cure-all for this disease.Zavesca could also be used for other purposes that are not mentioned in this guide.

Warnings

Nerve issues like tingling, numbness, or the tremor (shaking) of the hands are reported by some patients taking Zavesca. Consult your physician immediately if you notice an increase or worsening of numbness, burning, or tingling sensations in your hands, arms, legs, or feet, or tremors in your hands.

Follow the instructions on your prescription label and on the label of your package. Be sure to inform your healthcare professionals about your medical issues, allergies, and any other medications you take.

Before you take this drug

It is not recommended to use Zavesca if you are allergic to miglustat.

To be sure Zavesca is suitable for you, inform your physician if you suffer from:

  • Stomach problems;
  • An intestinal disorder like ulcerative colitis
  • Kidney disease kidney disease
  • A condition that can cause shaking.

Miglustat can cause harm to a baby who is not yet born. Use effective birth control methods to avoid pregnancy and notify your physician if you are pregnant.

It is unclear if the medication is absorbed into breast milk or whether it is harmful to the nursing infant. It is not recommended to breastfeed while taking Zavesca.Do not offer Zavesca to anyone younger than 18 years of age without medical advice.

How to take Zavesca?

Take Zavesca exactly as prescribed by your physician. Follow all the instructions on the prescription label. The doctor may modify the dose to make sure you're getting the greatest effects. Be sure to not take this medication in smaller or larger doses or for a longer period than the recommended time.

Zavesca is typically taken three times a day. It is recommended to take the medication in the exact same order every day.Your doctor must examine your muscle and nerve performance every six months when you're taking Zavesca.Make use of Zavesca often to reap the greatest benefits. Make sure you refill your prescription prior to running out of medication completely.Place it in a cool, dry place far from heat and moisture.

Details on dosage

Usual Adult Dose for Gaucher Disease:

Initial dosage: 100 mg taken orally, 3 times per day, at regular intervals.

What happens If I miss a dose?

Take the missed dose off, and then take the next dose at a regular time. Do not use two doses at one time.

Refill your prescription prior to the time that you are out of medication completely.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Zavesca can cause diarrhea, which can be very dangerous. Your doctor might prescribe a medication to treat diarrhea and also suggest changes to your diet.

Follow your doctor's advice regarding any restrictions on your food, drink, or activities.

Side effects of Zavesca

See a doctor immediately. If you experience any symptoms warning of an allergic reaction, such as hives, breathing difficulties, and swelling of your lips, tongue, throat, or face,

Contact your doctor immediately. If you suffer from:

  • A shake that is uncontrolled or tremors, especially in your hands
  • Tingling, numbness, and burning or numbness in your feet or hands;
  • Extreme weight loss and diarrhea;
  • Bleeding or bruising (nosebleeds, bleeding gums).

Common Zavesca adverse effects could include:

  • Gas, constipation, and bloating;
  • Nausea, stomach pain, vomiting, insatiableness, indigestion, and weight loss
  • Dry mouth;
  • Dizziness, weakness;
  • Migraine (including migraine);
  • Back muscles, back pain leg cramps, back pain
  • The feeling of pain or discomfort in your legs or arms;
  • Memory problems, feeling unstable and unstable;
  • Discomfort in the feet or hands;
  • Vision issues and vision problems
  • Changes in your menstrual cycle.

This isn't a complete list of all the side effects. Other effects may also be present. Consult your physician for advice regarding medical effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Other medications can be incompatible with Miglustat. This includes prescription and non-prescription medicines, such as vitamins and herbal products. Be sure to inform your health professionals about the medicines you take now and about any medication that you decide to stop or begin taking.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

CSA Schedule*

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