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Zyprexa (injection)

Generic name: Olanzapine (injection) [oh-LAN-za-peen]
The brand names are: Zyprexa, zyprexa Relprevv
Drug class: Atypical antipsychotics

What is the Olanzapine injection?

Olanzapine is an antipsychotic drug designed to address the symptoms associated with schizophrenia in adults. Olanzapine injections are not intended to be used daily to treat any psychotic disorder.

Olanzapine injection is available through a specific program. It is necessary to be enrolled in the program and be aware of the potential risks and benefits of using this medicine.Olanzapine injections can be used for other purposes not mentioned in this medication guideline.

Side effects of Olanzapine injection

Seek medical attention immediately in the event that you exhibit symptoms that indicate an allergy, such as symptoms of hives, breathing difficulties, and swelling of your lips, face, and tongue.

Get medical attention in the event of a serious drug reaction that affects the body in a variety of ways. Symptoms may include symptoms like skin eruptions, fever, swelling of the glands, influenza-like manifestations, muscle pain or weakness, severe uncommon bruising, or discoloration of your eyes or skin.

Olanzapine injections can trigger severe symptoms if the medication enters your bloodstream too quickly. In the initial three hours following your injection, you'll be screened for these signs:

  • Severe dizziness, drowsiness, or weakness;
  • Disorientation, anxiety, feelings of anger, or aggression;
  • Experiencing a feeling of nervousness or shaking;
  • Difficulties in walking or speaking;
  • Seizure (convulsions);
  • Feeling lightheaded, as if you're going to faint.

Zyprexa can result in severe adverse effects. See your physician right away If you have:

  • Uncontrollable or twitching movements of your lips, eyes, tongue, arms, or legs;
  • Difficulty swallowing or speaking;
  • Indications of symptoms of—if you are extremely thirsty and hot, not able to urinate, or suffer from excessive sweating or dry and hot skin;
  • Blood sugar levels are high—increased thirst, more frequent consumption of food, urination, dry mouth or breath odor that smells like fruit,
  • Extremely rigid (rigid) muscles and sweating, high fever, as well as confusion, quick or irregular heartbeats and shakes.

Common adverse effects of zyprexa can include:

  • Headache, back pain;
  • Weight increase (more likely to be experienced by teenagers) and increased appetite
  • Drowsiness;
  • Dry mouth, nausea, vomiting, diarrhea;
  • Sinus pain, a runny nose, nasal or stuffy nasal congestion, cough,
  • Itching after the injection.

This isn't an exhaustive list of possible side effects, and other side effects could be present. Contact your doctor for advice regarding medical adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Olanzapine injections can trigger signs of delirium (sudden extreme confusion, agitation, issues with walking or speech) or drowsiness serious enough to lead you into a condition known as a coma. You'll be observed carefully for at least 3 hours following the injection, and you should avoid driving for the remainder of the day.

Olanzapine injections are not a medical device that has been approved for elderly adults with dementia-related psychosis.

Before you take this drug

You shouldn't take this drug if you're intolerant of olanzapine.

Olanzapine can increase the likelihood of dying in elderly patients who suffer from dementia-related psychosis. It isn't approved for use in this manner.

If you can, before receiving the injection of olanzapine, you should inform your doctor that you've ever experienced:

  • Suicidal thoughts, actions, or thoughts;
  • The liver condition;
  • Heart disease: excessive and lower blood pressure;
  • The highest cholesterol or triglycerides
  • A stroke, including "mini-stroke";
  • Breast cancer;
  • A seizure;
  • Alzheimer's disease;
  • Diabetic, also known as high blood sugar
  • Increased prostate;
  • Bowel problems,
  • Narrow-angle glaucoma.

Consult your physician if you are expecting. Utilizing antipsychotic medications during the last three months of pregnancy can result in breathing and feeding issues, as well as withdrawal symptoms in newborns.Consult your physician if you are nursing. Olanzapine may pass into breast milk and cause adverse effects in the baby's milk.

In an emergency situation, you might not be able to inform the caregivers that you're nursing or pregnant. Be sure that any doctor who cares for your baby or is pregnant is aware that you have received this medication.Olanzapine injections are not intended to be used by anyone younger than 18 years of age.

How to take Olanzapine injection?

Olanzapine is injected into a muscle. It is administered in a hospital or clinic location.The olanzapine injection is usually administered only once. If you are still experiencing symptoms after two hours, your doctor could administer an additional or third dose.

Olanzapine injections can trigger symptoms of delirium (sudden extreme disorientation, confusion, and agitation, as well as difficulties with walking or speech) or drowsiness that are severe enough to lead you into insanity. The patient will be observed closely for at least 3 hours following the injection.

Do I be concerned if I miss a dose?

Because olanzapine injections are administered by a doctor in an emergency situation, you're not likely to not take an injection.

What will happen if I take excessively?

Since the medication is prescribed by a health specialist in a medical setting, it is highly unlikely for an overdose to occur.

What should be avoided?

Beware of drinking alcohol. Dangerous side effects may be experienced.Olanzapine can trigger severe sleepiness and affect your ability to think or react. It is recommended to stay in the hospital for a minimum of 3 hours following your injection, and you should avoid driving throughout the day.

Be careful not to get up too quickly from a lying or seated position where you could experience dizziness. The dizziness or extreme drowsiness could result in fractures, falls, or other injuries.

Interaction with other drugs

Utilizing olanzapine in conjunction with other medications that make you sleepy or slow your breathing could result in life-threatening or dangerous negative side effects. Ask your doctor prior to taking opioids such as a sleeping pill, a muscle relaxer, or medication to treat anxiety or seizures.

Other drugs can interact with Olanzapine, such as prescription and over-the-counter medicines, vitamins, and herbal products. Discuss with your physician your current medications and any medication you begin or stop taking.



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