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Zolpidem

Generic name: Zolpidem [zole-PI-dem]
Brand names: Ambien, Ambien CR, Edluar, Intermezzo, Zolpimist
The class of drug: Miscellaneous anxiolytics as well as sedatives and other hypnotics

What is Zolpidem?

Zolpidem can be described as one of the sedatives and is also known as a hypnotic. It can affect the chemicals in the brain, which could be out of balance in people suffering from sleep disorders (insomnia).

Zolpidem helps treat sleeplessness. The immediate-release versions include Ambien Intermezzo, Edluar, and Zolpimist, which are all used to aid you in falling asleep. Zolpidem's extended-release version is called Ambien CR, which has a primary layer that disintegrates quickly to aid you in falling asleep and a second layer that disintegrates slowly to aid in staying asleep.

Ambien, Edluar, Ambien, and Zolpimist are all used to help you fall asleep before going to sleep. Intermezzo is used to assist you in falling back to sleep when you awaken at night and then experience difficulty falling asleep.

Your doctor will decide which zolpidem dosage is best for you.

Warnings

Zolpidem could trigger an extremely severe allergy. Stop taking zolpidem and seek immediate medical assistance in the event that you experience any of the following symptoms, warning signs of an allergic reaction: an allergic reaction that causes hives, breathing difficulties, or swelling of your lips, face, and throat.

Don't give this medication to another person, even if they suffer from similar symptoms to yours. The doses recommended for zolpidem may differ for females and males. This medication is not recommended for use by children. Incorrect use of this drug can cause dangerous adverse consequences.

Zolpidem can affect your thinking or reactions. It is possible that you will feel tired in the morning following taking this medication, particularly if you're taking extended-release tablets or if you're female. You should wait at least 4 hours or until you're completely awake before doing things that require you to stay alert.

Do not take this medication in greater amounts or for a longer period than what is prescribed.

You should not use zolpidem if you have had a drink throughout the day or before going to bed.

Before You Take This Drug 

Some users of zolpidem may have engaged in activities like driving, eating, walking, making phone calls, or even having sex, and then forgotten about the event. If this is the case for you, discontinue taking zolpidem and consult your physician regarding a different treatment option for your case of sleep disorders.

It is not recommended to take this medication if you are intolerant to zolpidem. The tablets could contain lactose. Be cautious if you are allergic to lactose.

Zolpidem is not a drug that has been approved for use by anyone less than 18 years old.

To ensure that this medication is appropriate for you, tell your doctor if you have any of the following:

  • D. depression, mental illness, or suicidal ideas;

  • Alcohol or drug addiction

  • Acute lung disease or breathing issues;

  • Sleep apnea or sleepiness (breathing ceases while you sleep)

  • Kidney disease or liver disease

Zopidem use in the final three months of pregnancy can cause breathing difficulties or drowsiness for your baby.

It might not be safe to breastfeed while taking this medication. Consult your physician about any potential risks.

How to Take Zolpidom?

The doses recommended for zolpidem differ for women and men, and it is not recommended for use in children.

Follow the exact dosage as recommended by your physician. adhere to the directions on your prescription label and review all medication guidelines. Don't take this medication in greater amounts or for a longer period than prescribed. Talk to your doctor if you have a strong urge to take more medication or increase the dose.

Zolpidem could be habit-forming. Intoxication can result in addiction, overdose, or even death. Selling or giving the medicine away is a violation of the law.

Take note of and follow the instructions that are included with your medication. Talk to your pharmacist or doctor If you don't understand the instructions.

Don't use Ambien, Edluar, or Zolpimist in the event that you don't get 7-8 hours of sleep before returning to your active routine.

Don't take Intermezzo to treat insomnia in the middle of the night unless you've had 4 hours of rest prior to being active.

Zolpidem is intended for short-term use only. Consult your physician if insomnia symptoms don't improve or become worse after taking the medication for 7–10 consecutive nights.

Storage at room temperature, far from heat and moisture. Don't freeze. Place your medication in a secure location where nobody else can access it. Make sure to keep it upright in the Zolpimist container when it is not in use.

Do not stop taking the drug suddenly following long-term usage, or you could experience painful withdrawal signs. Consult your physician about how you can effectively stop taking this drug.

Sleeping disorders can recur after stopping the drug zolpidem. It could be more severe than it was before. Contact your physician if you are still experiencing worsening insomnia after the first couple of nights of taking the drug.

What Happens If I Miss a Dose?

Because zolpidem can be taken at night, if required, it is unlikely to skip a dose.

What Happens If I Overdose?

For medical emergencies, seek emergency treatment or contact the Poison Help line at 1-800-222-1222. A zolpidem overdose is fatal, especially when it is used in conjunction with other drugs that could result in drowsiness.

Overdose symptoms can include insomnia or confusion, fainting, feeling lightheaded, or fainting. They can also experience a coma.

Avoid this

Do not take zolpidem while travelling, like on a plane. It is possible to wake up after the effects of the medication have waned. The condition known as amnesia (forgetfulness) can be more frequent in the event that you do not receive an entire 7 to 8 hours of sleep following having taken this medication.

Avoid driving or engaging in hazardous activities until you understand how zolpidem affects you. You might be sleepy the next day, and your reactions may be affected. Be sure to wait until you're completely awake before you can drive or operate machinery, fly an aircraft, or perform any activity that requires you to be alert and awake.

Take this medication in the event that you've consumed alcohol throughout the day or before going to bed.

Side Effects of Zolpidom

Zolpidem can cause an extreme allergy. Stop taking this medicine immediately and seek medical assistance if you exhibit symptoms that indicate an allergy reaction to zolpidem, such as hives, breathing difficulties, and swelling of your lips, face, and tongue.

If you notice any new or deteriorating symptoms, tell your physician, including anxiety, depression, aggression anxiety, strange thoughts, hallucinations, memory disorders, or changes in your personality. taking risks, a decrease in inhibitions without anxiety about risk, or thoughts of self-harm or suicide.

Stop using this medicine immediately and consult your physician immediately if you are suffering from:

  • Chest pain, rapid heartbeat, or unsteady heartbeat sensation of shortness of breath;

  • Difficulty breathing or swallowing difficulty breathing or swallowing

  • Feeling like you might pass out.

The sedative effects of zolpidem can be greater for older adults. Drowsiness or extreme drowsiness could result in accidents, falls, or serious injuries. Common zolpidem side effects may include:

  • Dizziness, daytime drowsiness, fatigue, or the sensation that you are "drugged" or light-headed;

  • Tiredness, loss of coordination

  • Dry mouth, stuffy nose, or irritation of the throat;

  • Nausea, constipation, diarrhoea, upset stomach, or

  • Headache, Muscle pain.

This is not a comprehensive list of all the side effects. Other side effects could be experienced. Consult your physician for advice regarding medical adverse effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Details On Dosage

Usual Adult Dose for Insomnia:

IMMMEDIATE RELEASE (IR) Tablets, Oral Spray, and Sublingual Tablets (5 as well as 10 mg formulas):

Initial dose:

Women: 5 mg taken orally every day, just before bed.

Men: 5 to 10 mg daily, orally just prior to bedtime.

Maintenance dosage: 5–10 mg taken orally every day just prior to the time you go to bed.

Maximum dose: 10 mg/day

CONTROLLED/EXTENDED RELEASE (CR/ER) TABLETS:

Initial dose:

Women: 6.25 mg orally once per day, immediately before bed.

Men: 6.25 to 12.5 mg orally, once per day before the time you go to bed.

Dosage for maintenance: 6.25 to 12.5 mg orally, once per day before bed.

Maximum dose: 12.5 mg/day

SUBLINGUAL TABLETS (1.75 and 3.5 mg Formulations):

For women: 1.75 mg orally once every day at night, when needed.

Maximum dose: 1.75 mg/day

For men: 3.5 mg orally once every day at night, when it is required.

Maximum dose: 3.5 mg/day

Comments:

The recommended doses for men and women differ due to the lower level of clearance for females.

Clinical trials that support IR tablet efficacy ranged from 4 to 5 weeks' duration, whereas CR/ER tablet effectiveness was between 3 and 24 weeks.

The 1.75 mg as well as the 3.5 mg sublingual formulations should be used whenever a patient wakes up at night and has difficulty falling back asleep.

LIMITATION OF USE: 1.75 or 3.5 mg tablets are not suitable for treating insomnia among patients with less than four hours of sleeping time remaining prior to the scheduled time of awakening.

Uses:

IR Tablets, Oral Spray, and Sublingual Tablets (5 or 10 mg formulations) A short-term treatment for insomnia, characterised by problems with the initiation of sleep.

The CR/ER tablets are used to treat insomnia, which is characterised by difficulty with sleep onset or maintenance (as measured by the wake time after the onset of sleep).

Sublingual tablets (1.75 or 3.5 mg formulations) are needed for treating sleeplessness when an awakening in the middle of the night is followed by difficulty getting back to sleep.

Usual Geriatric Dose for Insomnia:

TABLETS WITH IR, ORAL SPRAY, and SUBLININGUAL Tablets (5 or 10 mg) 5 mg, orally, once daily, before bedtime.

Maximum dose: 5 mg/day

CR/ER TABLETS:

Patients aged 65 and over: 6.25 mg orally once every day, at night before bed

Maximum dose: 6.25 mg/day

SUBLINGUAL TABLETS (1.75 and 3.5 mg Formulations):

For patients over the age of 65: 1.75 mg once a night, as needed.

Maximum dose: 1.75 mg/day

Comments:

Doses are the same for both genders.

Clinical trials that support IR tablet efficacy ranged from 4 to 5 weeks in duration, whereas CR/ER tablet effectiveness was 3 to 24 weeks long.

The 1.75 Sublingual Tablet Formulations are to be taken whenever a patient awakes at night and has difficulty getting back to sleep.

LIMITATION OF USE: 1.75 Sublingual Tablet formulations are not recommended to treat insomnia in patients with less than four hours of sleep remaining prior to the scheduled time of awakening.

Uses:

IR Tablets, Oral sprays, and sublingual tablets (5 or 10 mg formulations) A short-term treatment for insomnia that is characterised by difficulty sleeping and waking up

Tablets (CR/ER): Treatment for insomnia that is characterised by problems in the onset of sleep and/or maintenance (as determined by the time it takes to wake after the onset of sleep)

Sublingual tablets (1.75 or 3.5 mg formulas) to be used to treat sleeplessness when an awakening in the middle of the night is followed by a difficult return to sleep

Interaction with Other Drugs 

Utilising zolpidem in conjunction with other medications that cause drowsiness can cause more of this. Consult your physician before taking an opioid drug, a sleeping pill such as a muscle relaxer, or medication for anxiety or seizures.

Numerous drugs can interfere with zolpidem, which can make it less effective or worsen the potential for adverse reactions. This includes prescription as well as over-the-counter drugs, vitamins, and herbal supplements. Not all interactions are included in this list. Inform your doctor of all the medications you are currently taking as well as any new medications you are about to start or stop taking.

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