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Generic Name: Plazomicin [PL-zoe-MYE-sin]
Drug Class: Aminoglycosides

What is Zemdri?

Zemdri is an antibiotic medicine that is used to treat infections that are serious for the kidneys or bladder.Zemdri may cause severe or debilitating adverse effects that might not be reversible. Zemdri should only be used for infections that can't be treated with a less harmful antibiotic.Zemdri could be used for other purposes that are not mentioned in this guide.

Side effects of Zemdri

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, or swelling of your lips, face, and tongue,

Zemdri may cause kidney damage, nerve damage, and the loss of hearing.

Consult your physician immediately if you are suffering from:

  • Intense stomach pains; diarrhea that is bloody or watery (even when it happens months after the previous dose);
  • Dizziness, spinning sensation;
  • The sensation of being lightheaded as you're passing out;
  • Hearing loss; a buzzing or roaring sound that is heard in your ear (during or following treatments with Zemdri);
  • Muscle weakness
  • Kidney problems: no or little urinary tract, swelling on your ankles or feet, and feeling tired.

Risky side effects are more frequent in older adults.

Common adverse effects of Zemdri include:

  • Nausea, vomiting, diarrhea;
  • Headache
  • Feeling lightheaded.

This isn't an exhaustive list of possible side effects, and other effects may also be present. Contact your physician to seek medical advice on the effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Similar/related drugs

Amoxicillin, Doxycycline, Ciprofloxacin, Augmentin, Levofloxacin, and Ceftriaxone


Zemdri could harm your kidneys. It could also result in hearing loss or nerve damage, especially if you suffer from kidney disease or take various other medicines.

Before you take this drug

You shouldn't make use of Zemdri in the event that you are allergic to Zemdri or other similar antibiotics, such as amikacin, kanamycin, gentamicin, paromomycin, streptomycin, or tobramycin.

Zemdri has not been approved to be used by anyone younger than 18 years old.

Speak to your doctor if you have ever suffered from:

  • Kidney disease
  • Disorders of the nerve, like myasthenia gravis.

Do not take Zemdri when you are pregnant. This medicine may cause hearing loss in the new baby. Make sure you use effective contraception during pregnancy and inform your doctor if you are pregnant.

It is not recommended to breastfeed while taking this medication. Talk to your doctor about any risks.

How to take Zemdri?

Follow the directions on the label of your prescription and read the medication guide or instructions sheets. Follow the medication exactly as prescribed.Zemdri can be administered in the form of an injection into a vein every 24 to 48 hours. Your healthcare professional will administer the first dose and guide you on how to apply the medication yourself.

Take note of and follow the instructions that are included with your medication. Don't take Zemdri when you aren't sure of the entire procedure for use. Talk to your pharmacist or doctor if you have any questions.Emdr is typically prescribed for a period of 4–7 days. Follow the doctor's instructions for dosage extremely carefully.Drink plenty of fluids when you use Zemdri.

It is possible that you will require frequent urine or blood tests. The kidneys, your hearing, and nerve function might also need to be examined.Place in the refrigerator and store. Do not freeze.The contents of each tube (bottle) are intended for only one purpose. It is discarded after just one use, regardless of whether there's still some medicine inside.

Make use of a needle or syringe just once, and then place them into the puncture proof "sharps" container. Be sure to follow the laws of your state or city on how to dispose of the container. Make sure it is out of reach of pets and children.

What happens If I miss a dose?

Take the medication as quickly as you can; however, do not miss any missed doses if you are nearing the time to take the next dose. Do not take two doses at once.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

The use of antibiotics can trigger diarrhea and could be an indication of a new disease. If you experience diarrhea that is bloody or watery, contact your doctor prior to applying anti-diarrhoea medications.

Interaction with other drugs

Zemdri may cause kidney damage, particularly in conjunction with specific medications for cancer, infections, osteoporosis, organ transplant rejection, intestinal issues, high blood pressure, or arthritis pain (including Advil, Motrin, and Aleve).

Other medications could influence Zemdri, such as prescription and non-prescription medicines, vitamins, and herbal products. Inform your physician about all the medicines you are currently taking and any medication you begin or stop taking.