The Web Health


Xpovio, 40 mg once a week

Name of the generic: selinexor Selinexor SEL-iNEX-or [SEL-i-NEX-or
Brand names: Xpovio 100 mg once-weekly; Xpovio 40 mg once-weekly; Xpovio 40 mg twice-weekly; Xpovio 60 mg once-weekly; Xpovio 60 mg twice-weekly; Xpovio 80 mg once-weekly; Xpovio 80 mg twice-weekly.
Classification of drugs: miscellaneous antineoplastics

What is Xpovio 40mg? twice weekly?

The Xpovio dosage of 40 mg once a week is combined with bortezomib or dexamethasone to treat multiple myeloma in adults.

Xpovio 40 mg twice a week is also taken by adults to treat certain forms of large B-cell lymphoma that are diffuse.Xpovio 40 mg twice a week is prescribed after other medicines fail or end their effectiveness.

Xpovio 40 mg twice a week is approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, a few individuals were able to respond positively to Xpovio 40 mg twice weekly; however, further research is required.Xpovio 40 mg twice a week may also be used to treat conditions that are not covered in this medication guide.

Side effects of 

Xpovio 40 mg

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as difficulty breathing, hives, or swelling of your lips, tongue, throat, or face.Xpovio 40 mg twice a week can trigger serious or fatal adverse effects. Certain side effects may not manifest until you've been taking the medicine for a few days or weeks.

Xpovio 40 mg twice a week can result in serious unwanted side effects. Consult your doctor immediately If you have:

  • Blurred vision blurred vision, blurred vision, eye pain, or seeing halos of light sources;
  • Severe ongoing nausea, vomiting, or diarrhoea;
  • Lack of appetite that stops you from eating and can cause weight loss;
  • Dizziness, confusion, fainting, or changes in mental state;
  • Signs, warning signs sepsis signs of sepsis the symptoms of sepsis are fever and chills. Extreme fatigue and rapid heartbeats fast breathing and feeling sick;
  • Symptoms of signs of fever symptoms of infection such as chills symptoms of flu, such as chills and fever manifestations, cough with mucus, throat and mouth ulcers, feeling tired, sensation of tingling or pain in the rash on the other part of the body,
  • Low sodium level low sodium level, headache, and slurred speech. Nausea, severe weakness, and loss of coordination. Feeling unstable.

The treatment you receive might be delayed or stopped if you experience specific adverse reactions.

Common adverse effects of Xpovio 40 mg twice a week could include:

  • Blurred vision, double vision, and sensitivity to light glare
  • Tiredness;
  • Tingling, numbness, and burning sensations in your feet or hands;
  • Anaemia, bleeding, bruising, or bleeding
  • Higher blood sugar levels
  • Infection, fever, cold, or symptoms of the flu;
  • Variations in mineral and sodium levels;
  • Irregular kidney or liver function tests;
  • Nausea and vomiting, as well as a lack of appetite.
  • Diarrhoea, constipation;
  • Weight loss;

This is not a comprehensive list of possible side effects, and other side effects could be present. Contact your physician for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Similar or related drugs

Darzalex, Blenrep, Tecvayli, Carvykti, prednisone, rituximab, and cyclophosphamide


It is possible to contract infections more often, including severe or fatal infections. Call your doctor if you are suffering from a fever or chills, flu symptoms, mouth ulcers, a cough, or breathing difficulties.The Xpovio 40 mg dose twice a week may cause lower blood platelet counts. Inform your doctor immediately in the event of unusual bruises or bleeding.

Before you take this drug

Inform your doctor if you have ever suffered from:

  • Cataracts;
  • Bleeding issues as well as
  • Active or recent infections.

It is possible that you will need to take an unfavourable pregnancy test prior to beginning this treatment.

Men and women who are taking Xpovio 40 mg twice a week must use effective birth control to avoid pregnancy. Xpovio 40 mg twice a week can harm an unborn child when the father or mother is taking this medication.Continue using contraceptives for a minimum of one week following the last dose. Contact your doctor immediately when you become pregnant and one of the parents or father is taking Xpovio 40 mg twice a week.

This medication can affect fertility (ability to have kids) in both males and females. But it is crucial to utilise birth control to stop pregnancy, as Xpovio 40 mg twice a week could harm a baby who is not yet born.Avoid breastfeeding during the course of this medication and for at least a week following the last dose.Not authorised to be used by anyone less than 18 years old.

How to take Xpovio 40 mg once a week?

The doctor will run tests to determine if Xpovio 40 mg twice a week is the best treatment for you.Follow all the instructions on the label of your prescription and read the medication guide or instructions sheets. The doctor might change the dosage. Be sure to take your dosage exactly as directed.

The Xpovio 40 mg dose twice a week is usually taken on specific days, usually once or twice a week. Follow your doctor's directions carefully regarding when and how to take this medication with dexamethasone, bortezomib, orYour physician will determine how long you will be treated with Xpovio 40 mg once a week and dexamethasone.

Consume Xpovio 40 mg once a week with a full glass of fluid. Suck the tablet whole and don't crush, chew, or tear it.If you experience vomiting shortly after having taken Xpovio 40 mg twice weekly, don't take a second dose. The next dose should be taken as per the schedule.

There are other medicines to prevent nausea, vomiting, infections, or nausea. Take these medications for the duration your doctor prescribes.It is possible to contract infections more often, or even fatal or serious infections. You'll require frequent medical tests. It is possible to require a transfusion if your platelets in your blood become too low.

The levels of sodium in your blood are required to be checked. If your levels are low enough, your doctor might suggest salt-based tablets or even intravenous (IV) fluids to prevent your body from becoming dehydrated.Take plenty of fluids to avoid dehydration. Also, take in enough calories to stop the loss of weight.

Xpovio 40 mg twice a week may affect your appetite or capacity to consume food. The weight of your body will be measured prior to or during your treatment to ensure you're not losing weight while taking this medication.Keep the tablets at room temperature and free of heat and moisture. Store every Xpovio 40 mg tablet twice weekly within the package until the point of taking your dosage.

What happens if I miss a dose?

Don't miss the dose you missed, and re-take your dose according to the time you normally take it. Don't take two doses at the same time.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Avoid driving and other hazardous activities until you understand how Xpovio 40 mg twice a week can affect you. Your reaction could be affected.

Interaction with other drugs

Other medications that can influence Xpovio 40 mg twice a week include prescription and non-prescription medicine, vitamins, and herbal supplements. Discuss with your physician all the other medications you take.




Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories