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Torsemide

Generic Name: Torsemide (oral or injection) [TOR-se-mide]
Brand Names: Soaanz, Demadex, and Demadex I.V.
Dosage Format: Oral tablet (10 mg; 100 mg; 20 milligrammes; 40 mg; 5 mg; 60 mg)
Drug Class: Loop diuretics

What is Torsemide?

Torsemide is an ointment loop diuretic (water pill) that is prescribed for the treatment of the problem of fluid retention (oedema) in patients suffering from heart disease, liver disease, or kidney disease.

Torsemide may also be utilized to manage hypertension (hypertension). The reduction in blood pressure could reduce the chance of having a stroke or heart attack.Torsemide is also used for reasons not mentioned in this guideline.

Side effects Torsemide

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as hives, difficulty breathing, or swelling of your lips, face, and tongue.

Contact your doctor immediately. If you suffer from:

  • A feeling of lightheadedness, as if you're passing out;
  • Ringing in your ears unintentionally causes loss of hearing;
  • Kidney problems: no or little urinary tract infection, difficulty or pain to urinate, swelling on your ankles and feet, and feeling exhausted or sluggish;
  • Low magnesium levels, dizziness, and irregular heartbeats. Feeling nervous, muscle cramps, muscle spasms, coughing, or choking feeling
  • Lower potassium level; leg cramps constipation, irregular heartbeats, fluttering around your chest, increased thirst, or urination Numbness or sensation of tingling, muscle weakness, or a limb sensation;
  • Low sodium levels cause headaches and confusion. It can also cause poor speech, extreme weakness, vomiting, and a lack of coordination. Feeling unsteady.

Common adverse side effects of torsemide include:

  • An increase in urination;
  • Headache.

This isn't a complete list of possible side effects, and other effects may also be present. Contact your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Warnings

Torsemide is not a good choice when you have an allergy to sulfa medications or are not able to urinate.

Before you Take this Drug

It is not recommended to use torsemide if your body is allergic to it or if you suffer from:

  • You aren't able to urinate,
  • You are sensitive to orally administered diabetes medication.

Inform your doctor if you have ever suffered from:

  • Coronary disease;
  • Kidney issues (unless there is a reason to take torsemide to treat kidney disease-related oedema);
  • Liver issues, such as liver problems like cirrhosis or hepatitis (unless the medication is to treat the oedema that is caused by an underlying liver condition);
  • Gout;
  • An allergy to the povidone (sometimes present in the iodine, betadine) or
  • If you're on a diet that has low salt.

If you require any type of x-ray or CT scan that uses an injection of dye into your veins, inform your medical professionals that you are currently taking the medication torsemide.

Inform your doctor if you are expecting or planning to be pregnant. It isn't known if the drug torsemide can harm an unborn baby. But having hypertension during pregnancy could result in complications like eclampsia or diabetes (dangerous hypertension that could cause medical issues in both the mother and the baby). The advantages of treating hypertension could outweigh the risks for the baby.It is not suggested to feed your baby while you take the medication. Talk to your doctor about any risks.

Torsemide is not a drug that has been approved to be used by anyone younger than 18 years of age.

How to Take Torsemide?

Follow the instructions on your prescription label and go through all medication guides or instructions. The doctor might alter your dosage. Follow the medication exactly as prescribed.The oral form of torsemide is administered by mouth.

Torsemide injections are given as an injection into a vein. Healthcare professionals can teach you how to use the medication on your own. Torsemide injections are given as a steady infusion for two minutes or as a continuous (around the clock) infusion.If you suffer from cirrhosis or any other liver issue, it is possible to get an initial injector in an institution or clinic to treat any adverse negative side effects.

Be sure to read and adhere to any instructions that are included with your medication. Talk to your pharmacist or doctor to clarify any instructions.Only inject when you are able to. Avoid using any medicine that changes color or has particles. Consult your pharmacist about the latest medication.You can take torsemi either with or without food.

Your blood pressure is likely to be checked regularly, and you might require other tests for medical reasons. The urine and blood could be tested in the event that you've had a stomach upset or are dehydrated.Certain things could cause blood pressure levels to go too low. This could include nausea, diarrhea, or excessive sweating. Contact your physician if you have a stomach ache or diarrhea.

Your medical condition could be treated using a combination of medicines. Follow all medications as prescribed by your physician. Don't alter your dosages or your medication schedule without a physician's guidance.If you suffer from elevated blood pressure, continue taking torsemide even if you feel good. The presence of high blood pressure is often accompanied by no signs. It is possible that you will need medication for high blood pressure throughout your life.Maintain room temperature and far from moisture and heat.

Details on Dosage

Usual Adult Dose for Oedema:

Oedema which is associated with Congestive Heart Failure:
IV and oral 10 to 20 mg daily If diuresis is not sufficient and you are unable to achieve it, increase the dosage until you get the desired effect. Single doses greater than 200 mg haven't been studied thoroughly.
Oedema that is a result of renal disease
Oral and IV 20 mg taken once per day If diuresis is inadequate, titrate up by about double the dose until the desired response is reached. Doses that are higher than 200 mg haven't been studied thoroughly.
Oedemas that are associated with hepatic disease:
Injection and orally: 5–10 mg once daily using an aldosterone antagonist or a diuretic with potassium-sparing properties. If diuresis is not sufficient and you are unable to achieve a satisfactory response, increase the dose by about double the dose until the desired effect is reached. Single doses greater than 40 mg haven't been studied thoroughly.
Comments: The long-term use of diuretics for liver disease hasn't been thoroughly studied.

Usual Adult Dose for Hypertension:

5 mg taken orally every day. If diuresis is insufficient after 4 to 6 weeks, increase the dose to 10 mg orally every day. If diuresis continues to be inadequate after 10 mg, an antihypertensive medication should be considered.

What Happens If I Miss a Dose?

You should take the medication as quickly as you are able, but avoid any missed doses if it's close to the time of the next dose. Don't take two doses at once.

Consult your doctor when you have missed the dose of the torsemide injectable.

What Happens If I Overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

The symptoms of an overdose could be dehydration or unbalanced electrolytes (such as low magnesium, potassium, and sodium levels in the blood), as well as the presence of low blood pressure and fainting.

What Should be Avoided?

Avoid becoming too hot or dehydrated during workouts, in hot weather, or by drinking insufficient fluids. Follow your doctor's advice on the kind and quantity of fluids you need to consume. In certain situations, drinking too much liquid could be as dangerous as drinking too little.

Interaction with Other Drugs

Inform your doctor about all the medications you take. Numerous drugs can affect the metabolism of torsemide, particularly:

  • Any other diuretic medication;
  • Cholestyramine and lithium; phenytoin, probenecid; rifampin, warfarin (Coumadin, Jantoven)
  • An intravenous (IV) antibiotic medicine;
  • Antifungal medicine (fluconazole, miconazole);
  • Heart or blood pressure medicine—amiodarone, dronedarone, enalapril, irbesartan, lisinopril, losartan, olmesartan, valsartan, and others;
  • These are NSAIDs (nonsteroidal anti-inflammatory drugs): ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac (indomethacin), diclofenac, and many others;
  • Salicylates--aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others
  • Steroid medicine—dexamethasone, oxandrolone, prednisone, and others.

This list isn't complete, and other drugs could influence the effects of torsemide. This includes prescription and over-the-counter drugs, vitamins, and herbal supplements. The interactions of all drugs are listed here.

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