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Angeliq

Generic Name: of Drospirenone and Estradiol [droe-SPYE-re-none and Estra DYEL]
Drug Class: Description for Sex Hormone Combinations

What is Angeliq?

Angeliq contains a mix of drospirenone and estradiol. Drospirenone is a female hormone that helps regulate menstrual cycles and ovulation. Estradiol is a hormone for females that is involved in the growth and maintenance of the female reproductive system.Angeliq helps treat menopausal symptoms like hot flashes, dry vaginal lining, and irritation. It also helps with burning.Angeliq is intended for use only when you have a uterus (if you haven't been through surgery to remove your uterus).

Warnings

It is not recommended to use Angeliq. If you suffer from undiagnosed vaginal bleeding in the coronary artery or a bleeding problem, liver disease, kidney disease, or an adrenal gland condition, if you're scheduled to undergo major surgery, when you've had a hysterectomy, or if you've ever suffered from a cardiac attack or stroke, blood clots, or cancer of the breast, uterus, cerevix, or vagina,Do not take Angeliq when you are pregnant.Angeliq can increase the risk of developing an illness that can cause the development of uterine cancer. If you notice any unusual vaginal bleeding, act immediately.This medicine may increase the chance of developing blood clots and strokes, heart attacks, and cancer of your uterus, breast, or ovaries. Angeliq should not be used to treat stroke, heart disease, or Alzheimer's disease.

Before you take this drug

You shouldn't take Angeliq in the event that you are allergic to drospirenone and estradiol or if you suffer from

  • Abnormal vaginal bleeding that the doctor hasn't checked;
  • A bleeding disorder;
  • Coronary artery disease
  • An occurrence of a heart attack, stroke, or blood clots
  • Kidney disease;
  • Liver disease;
  • An adrenal gland disorder
  • An antecedent history of hormone-related cancer such as breast cancer, vagina, uterus,
  • If you've taken your uterus out (hysterectomy),

Do not take Angeliq when you are pregnant. Tell your doctor immediately if you find yourself pregnant while taking treatment.This medicine may increase the risk of stroke, blood clots, and heart attacks. You're more at risk if you suffer from hypertension or diabetes, excessive cholesterol, or if you're overweight or smoke.Angeliq is not recommended to treat stroke, heart disease, or dementia because the medication could actually increase the chances of developing these illnesses.

Inform your doctor if you have ever suffered from:

  • Heart disease, high blood pressure
  • A thyroid disorder
  • Gallbladder disorder;
  • Jaundice due to pregnancy or the use of hormonal medications;
  • Triglycerides with high levels (a kind of blood fat);
  • Asthma;
  • Epilepsy or any other seizures;
  • Migraine headaches;
  • Lupus;
  • Endometriosis or uterine fibroid tumours;
  • Excessive levels of potassium or calcium in your blood or low sodium level
  • Hereditary angioedema (an immune system disorder);
  • Porphyria (a genetic disorder of enzymes that can cause symptoms in the nervous system or skin).

Utilising Angeliq can increase the chances of getting breast cancer. Consult your doctor regarding your risk prior to using this drug for a long time.This medication reduces the hormone that is needed to make breast milk and may slow down the production of breast milk. Do not breastfeed when taking Angeliq

How to take Angeliq?

You should take Angeliq exactly as directed by your physician. Follow all instructions listed on your prescription label, and review any medication guides or instruction sheets provided with the medication.Don't chew, crush, break, dissolve, or crush an Angeliq tablet. Take it in whole.Use this medicine every day.Angeliq can increase your chance of developing an illness that could cause the development of uterine cancer. Your doctor could prescribe progesterone to lower the risk. Inform your doctor of any unusual vaginal bleeding promptly.If you are in need of major surgery or are being placed on bed rest for long periods of time, you may have to discontinue using this drug for a short period of time. Any surgeon or doctor who cares for you must know that you're using Angeliq.

Your doctor should examine your improvement every month to determine if you need to keep taking thismedication. Check the breasts to detect lumps and bumps on a regular basis, and undergo regular mammograms while taking this medication.Keep it at room temperature, far from heat and moisture.

Details on dosage

Usual Adult Dose for Postmenopausal Symptoms:

Vasomotor symptoms:
1 0.25 mg drospirenone/0.5 mg estradiol tablet, taken orally every day
OR
A 0.5 mg of drospirenone/100 mg of isradiol tablet taken orally, once per day
The vulvar as well as vaginal atrophy:
0.5 mg of drospirenone, or 1 mg of isradiol tablet, taken orally every day
Comments:
Treatment is continuous.
Women who aren't on oestrogens or a continuous combination drug can begin treatment at any time.
Women switching to continuous, sequential, or cyclic hormone therapy should finish their current cycle prior to changing.
When used solely for vaginal atrophy and vulvar, you may want to consider vaginal topical products.
Uses: Treatment for moderate to severe vasomotor signs and vaginal and vulvar atrophy due to menopausal

What happens if I miss the dose?

Do the medication as quickly as you can. However, avoid your missed dose if you exceed 12 hours late for the dose. Do not take two doses at the same time.

What happens if I overdose?

For medical emergencies, seek emergency attention or contact the Poison Help Line at 1-800-222-1222. The symptoms of an overdose can consist of vomiting, nausea, vomiting, and vaginal bleeding.

What should be avoided?

Don't smoke. It could greatly increase the chance of developing stroke, blood clots, or a heart attack when you are taking this medication.Grapefruit can interact with estradiol and drospirenone and cause unwanted adverse effects. Beware of using grapefruit-related products.

Side effects of Angeliq

See a doctor immediately in the event that you exhibit symptoms of an allergic reaction, such as hives, breathing problems, or swelling of your lips, face, or tongue.

Contact your doctor immediately. If you suffer from:

  • Warning signs of heart attacks heart attack symptoms: chest pain, pressure, pain that is spreading into your shoulder or jaw, nausea, sweating;
  • Indications of stroke sudden weakening or numbness (especially on the opposite side) and sudden extreme headache and slurred speech. Issues with balance or vision;
  • Symptoms of the presence of a blood clot: sudden loss of vision and chest pain that is stabbing, feeling breathless, bleeding blood, coughing up blood, discomfort or warmth on one or both legs;
  • Sudden vision loss;
  • Swelling rapidly, gaining weight;
  • Jaundice (yellowing of the eyes or skin);
  • Memory issues or confusion, abnormal behaviour;
  • Unusual vaginal bleeding
  • A bump in the breast
  • Blood sugar levels are high increasing thirst, increased urination the mouth is dry, and there's a fruity smell.

Common angeliq side effects can include:

  • Mood changes, headaches;
  • Vaginal discharge or itching or discharge from your vagina; changes in your menstrual cycle; breakthrough bleeding;
  • Discomfort in the breast;
  • Sickness, diarrhoea, stomach pains, or nausea;
  • Fluid retention (swelling, rapid weight gain).

This isn't an exhaustive list of all the side effects. Other effects may also be present. Consult your physician to seek medical advice on the effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Interaction with other drugs

It is sometimes not safe to take certain medications simultaneously. Certain medications can alter the blood levels of the other drugs that you take, which can cause more side effects or make the drugs less effective.Other medications can be incompatible with estradiol and drospirenone, which include prescription and over-the-counter medicines, vitamins, and herbal products. Inform your physician about all your medications currently in use and any medication you begin or stop taking.

 

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

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