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Abacavir, Lamivudine, and Zidovudine

The Generic Name is: Abacavir, Lamivudine, and Zidovudine

Name of Brands: Trizivir

Format for Dosage: Tablet

Drug classification: Antiretroviral Agent, Nucleoside Reverse Transcriptase Inhibitor (NRTI) Combination

What is Abacavir, Lamivudine, and Zidovudine?

Abacavir, Lamivudine, as well as Zidovudine are added to form the fixed-dose combination medicine which is prescribed to treat HIV (Human Immunodeficiency Virus) disease. The combination tablet is often identified by its brand name Trizivir. The medications in this mixture fall under nucleoside reverse transcription inhibitors (NRTIs) and are used together to block the replication of the virus.


  • Hypersensitivity that is severe and possibly fatal reactions have been linked to Abacavir usage. Genetic testing is advised before starting treatment to determine people at risk of developing this type of reaction.
  • Stop the medicine immediately. Do not reintroduce when a hypersensitivity reaction is suspected.

Before Taking The Medication:

Before starting Abacavir, Lamivudine, and Zidovudine, be sure to inform your physician regarding any medical issues you may have, like kidney disease, liver disease, or any other known history of drug allergies.

How to Take Abacavir, Lamivudine, and Zidovudine?

  • Abacavir, Lamivudine, and Zidovudine are usually used orally as a tablet daily, in combination with or without food, following your doctor's instructions.
  • Be sure to follow your physician's recommendations concerning dosage and time.

Specifics on Dosage:

The dose of Abacavir, Lamivudine, and Zidovudine are set by your doctor according to factors such as your body weight, your medical history as well as other medicines you might be using.

What Happens If I Miss a Dose?

If you miss a dose, take it when you can remember. But if you're just before the date for the next dose, you can skip the dose you missed and proceed by following the regular dosing schedule.

What Happens If I Overdose?

In case of an overdose, you should seek medical attention right away. The symptoms of an overdose could be nausea, vomiting, fatigue, and problems getting to sleep.

What Should be Avoided?

  • Avoid discontinuing Abacavir or Lamivudine. Zidovudine unless you consult your physician because it could cause a reduction in efficiency in HIV treatment.
  • Beware of drinking alcohol while you take the medication, as it could increase the chance of adverse reactions.

Side effects of Abacavir Lamivudine and Zidovudine Minor Effects Some common adverse effects could be:

  • Nausea
  • Headache
  • Diarrhea
  • Fatigue

Negative Effects: Serious adverse effects may be a result of:

  • Hypersensitivity reaction (fever, itching, rash, nausea, vomiting, abdominal discomfort)
  • Lactic acidosis (unusual muscles pain, trouble breathing, and stomach discomfort)
  • Bone Marrow Suppression (Zidovudine)

Interactions with Other Drugs:

Inform your doctor of all the medicines you take that are not prescription drugs and herbal supplements. Abacavir, Lamivudine, and Zidovudine may interact with other drugs, particularly those that affect the bone marrow and liver.



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