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Saliva substitutes

Generic name: saliva substitutes [sa-LYE-va-SUB-sti-tutes]
The brand names are: Aquoral, Biotene Dry Mouth, Biotene Moisturizing Mouth Spray, Biotene Mouthwash, Biotene Oral Balance, etc. Show all 36 names.
Forms of dosage: oral gel (-), or lozenge for oral use (-), powder to use to reconstitute (-), oral solution (-), or spray (-),… display all six dosage forms
Classification of drugs: mouth and products for the throat

What are Saliva substitutes?

Saliva substitutes are artificial versions of mucus-secreting mucus that are normally produced by the mouths of humans. These substitutes aid in the creation of artificial saliva in the event that the body does not produce enough saliva on its own.

Saliva substitutes aid in relieving dryness and pain as well as discomfort within the throat and mouth that could be caused by certain medical conditions, such as medication, surgery, radiation therapy, and chemotherapy.They can be used to treat conditions that are not covered in this guideline for medication.

Side effects of Saliva substitutes

See a doctor immediately. Get medical attention immediately if you notice symptoms or warning signs of an allergic response, such as symptoms of hives, difficulty breathing, or swelling of your lips, face, or tongue.

It's not a complete listing of all possible adverse reactions, as other things may occur. Consult your physician for guidance about medical-related adverse reactions. It is possible to report any adverse reactions to the FDA by calling 1-800-FDA-1088.


There are numerous types of brands and substitutes that are available. Some brands are not included in this leaflet. Follow the directions on the label of your medication and packaging.

Before you take this drug

It is not recommended to apply saliva substitutes if you have an allergy to one of the components in the package.Talk to your doctor before using saliva substitutes if you are breastfeeding or pregnant.

Similar/related drugs

pilocarpine, chlorhexidine topical, Peridex, Glycerin topical, Salagen, sodium the topical hyaluronate, and Biotene Mouthwash

How to take Saliva substitutes?

An alternative to saliva is intended for use only inside the mouth. Don't get it into your eyes.Use the product for saliva precisely as indicated on the label or as directed by your physician.Saliva substitutes function inside the mouth and aren't intended to be swallowed.For the use of the oral rinse or other liquid saliva products, you can just swish a small amount into your mouth over 30 minutes and then take a spit.

The powder for oral use must be mixed with around 1 ounce of water prior to taking it. Stir the mixture before using it immediately, even if you have to shake it 2-3 times in order to get the complete amount. Don't save the mix to use later on.Shake the spray gently prior to each application, and then spray directly into the mouth and onto your tongue.

Lozenges or tablets could be kept in the mouth for extended periods, even while asleep. Certain tablets are stuck to the gums or teeth to keep them in position.Gels, pastes, or swabs can be sprayed directly on the tongue, gums, teeth, or the sides. Be sure to follow all directions carefully.

The frequency with which you use the saliva substitute could depend on your medical condition or prescription schedule.Most often, it is recommended to use saliva substitutes up to five times a day or when your mouth is discomforting and dry. When you undergo radiation or chemotherapy treatment, you may need to take saliva substitutes up to 10 times a day, starting on or prior to the day of treatment. Follow all dosage instructions meticulously.

Do not permit a child to make use of saliva substitutes in the absence of adult supervision.The use of saliva substitutes is part of a total treatment program that incorporates other methods for oral hygiene. Follow the directions of your doctor precisely.Make sure you store your saliva substitute according to the instructions indicated on the label. Beware of heat, moisture, and light.

Do I be concerned if I miss a dose?

Since saliva substitutes are only used whenever needed, you may not be following a dose schedule. If you're on a schedule, you should take the dose you missed as soon as you can remember. Avoid your missed dosage if it's nearing the time for the next dose scheduled. Do not take extra medication to make up for the missed dose.

What will happen if I take excessively?

A saliva substitute is unlikely to be a danger. Take immediate medical attention or contact the Poison Help Line at 1-800-222-1222 if you've accidentally swallowed huge amounts of this substance.

What should be avoided?

It is possible to not drink or eat anything for 15 minutes after using salivary replacements. Follow all the instructions on the labels of the products that you are using.Rinse thoroughly with water if a saliva substitute is able to get into your eyes.

Interaction with other drugs

It is unlikely that other drugs you consume in the form of injections or oral medication will affect saliva substitutes that are used in the mouth but not swallowed. However, many medications can interact with each other. Be sure to inform your health care professionals about any medications you take, including prescription and non-prescription medications, vitamins, and herbal remedies.