Sutent

What is Sutent?

Sutent is a cancer treatment which blocks the spread and growth of cancerous cells within the body. Sutent is a prescription medication for treating certain kinds of progressive or advanced stomach tumors stomach, intestines and esophagus, pancreas, or kidneys.. It isn't clear whether Sutent is secure and effective for children.

Warnings

Sutent may cause serious or even fatal consequences to the liver. You will need frequent blood tests to assess your liver's health during treatment. Consult your physician if notice any indications of liver problems for example, the upper stomach hurting on the right side or irritation, dark urine as well as jaundice (yellowing of the eyes or skin).

Before you start taking this medicine

Sutent is not a good option for you. Sutent in case you have an allergy to sunitinib.

To make sure that Sutent is suitable for you, inform your doctor if ever experienced:

• kidney disorders other than cancer
• liver disease;
• coronary heart diseases, excessive blood pressure;
• lower blood sugar or diabetes
• bleeding issues;
• Long QT Syndrome (in either you (or a member of your family);
• an thyroid disorder; or
• surgery (or the possibility of having surgery undergo surgery).

This medication could cause jaw bone issues (osteonecrosis). The risk is greatest for those suffering from cancer or bleeding disorders in blood cells, existing dental issues, or those receiving chemotherapy, steroids or radiation. Talk to your doctor about the risk you are taking.

Sunitinib may cause harm to an unborn baby as well as cause birth defects when the father or mother is taking this medication.

• If you're female, do not use Sutent when it is believed that you're pregnant. It is possible that you will need a pregnancy test that is negative prior to taking this medication. Utilize effective birth control methods to stop pregnancy while using this medication, and for a minimum of 4 weeks following your last dose.
• If you're male, use effective birth control when your partner can get pregnant. Continue using birth control for a minimum of 7 weeks following your last dose.
• Contact your physician immediately If you become pregnant during the time that both the mother and father is taking Sutent.

Sunitinib can alter the fertility (ability for having children) for both men as well as women. But, it is important to utilize birth control to stop pregnancy as sunitinib could harm a newborn baby. It is not recommended to breastfeed while you are taking Sutent or for more than 4 weeks following the last dose. by anyone less than 18 years of age.

How to take Sutent?

Use Sutent exactly as directed by your physician. Follow the directions on the prescription label and go through all the medication guides or instructions sheets. The doctor might modify your dose.

The liver's function and blood pressure could need to be checked at the start of each 4 week treatment program. Sutent is typically taken one time every day. Sutent may be used for four weeks, followed by two weeks of abstinence from the medication. Your physician will decide the amount of treatment cycles you will require depending on your medical condition. Sutent can be taken in combination with food or not.

Do not chew, crush or break Sutent capsules. Inhale it completely. The medicine in broken or crushed pills could be harmful when it is absorbed into your skin. If this happens, wash your skin with soap and water, then clean it thoroughly.It is essential to have regular urine and blood tests. The heart's function could be checked by Electrocardiogram (ECG also known as EKG) frequently as well as require regular dental examinations.If you require an operation or dental procedure inform the dentist or surgeon you currently utilize Sutent. It is possible to stop taking the medication for a short period of time prior to or after major surgical procedure.Keep at room temperature, far from heat and moisture.

Details on dosage

Usual Adult Dose for Renal Cell Carcinoma:

50 mg once a day orally at a frequency of 4 weeks treatment, then 2 weeks of no treatment

Comment: Take without or with food.

Uses:
For the treatment of the advanced renal cell cancer (RCC)
For the treatment of gastrointestinal tumors (GIST) following progression of the disease in or an intolerance Imatinib.

Usual Adult Dose for Gastrointestinal Stromal Tumor:

50 mg once daily orally in a time frame of 4 weeks for treatment, followed by two weeks of no treatment

Comment: Take in combination with or without.

Uses:
For the treatment of advanced renal cell cancer (RCC)
For treatment of gastrointestinal tumors (GIST) following progression of the disease or intolerant to imatinib.

Usual Adult Dose for Pancreatic Cancer:

37.5 mg once a day, orally

Comments:
To be taken continuously, without any scheduled off-treatment time or in combination with food or not.

Use: To treat of pancreatic cancer that is well-differentiated and progressive. neuroendocrine tumors (pNET) in patients suffering from unresectable locally advanced metastatic disease.

What happens if I miss a dose?

Take the medication as quickly as you are able, but do not take your missed dose in case exceed 12 hours behind on the dose. Do not take two doses at once.

What happens if I overdose?

Get medical attention in an emergency or contact for help at the Poison Help line at 1-800-222-1222.

What should be avoided?

Grapefruit can interact with sunitinib, leading to adverse negative side consequences. Do not use grapefruit-related products.

Sunitinib is a drug that can be absorbed into body fluids (urine and feces, as well as vomit). Caregiver's should wear gloves made of rubber to clean up the person's bodily fluids contaminated garbage or laundry, or changing diapers. Clean hands prior to and after taking off gloves. Cleanse linens and clothing that has been soiled apart from the rest of the laundry.

Side effects of Sutent

See a doctor immediately when you notice symptoms warnings of an allergy reaction Sutent (hives and breathing difficulties or swelling in your throat or face) or an extreme skin reaction (fever and throat soreness burning eyes, skin ache as well as a red or purple itching that can cause peeling and blisters). Sunitinib could cause severe or fatal consequences to the liver. Call your doctor in case you experience an appetite loss or stomach discomfort (upper right side) fatigue and itching and dark urine, stools that are clay-colored as well as jaundice (yellowing of the eyes or skin).Sutent can also trigger life-threatening blood clots within the blood vessels that are small inside your organs, like kidneys or the brain. Seek medical help immediately if you notice symptoms of this disorder including fatigue, fever or a decrease in urination, bleeding or nosebleeds.

Make sure to contact your doctor the earliest opportunity if you are suffering from:

• Redness, pain, numbness or peeling of the skin feet and hands;
• simple bleeding, unusual bruising the appearance of red or purple spots beneath your skin
• Sores and skin irritations that are painful on your lips or in your lips;
• Jaw pain, numbness or gums that are swollen or red loose teeth, or slow healing after dental surgery;
• issues with thinking, confusion and seizures;
• Heart issues swelling and weight gain rapid, quick or pounding heartbeats an enthralling chest or breath shortness and suddenly dizziness (like you're going to faint);
• Higher blood pressure high blood pressure - extreme headache blurred vision the pounding of your neck or ears, nausea;
• Low blood sugar - headache, hungry in the morning, weakness, sweating rapid pulse, sensation of anxious;
• Indications of bleeding within your body changes within your mood and urine that is bloody as well as swelling and pain in your stomach bloody or tarry stool and coughing blood, or vomit that appears to be coffee grounds.
• Indications of a tumor cell's breakdown fatigue, weakness muscle cramps nausea, vomiting, diarrhea, slow or fast beat, and tingling sensations in your feet, hands and fingers as well as around your mouth or
• Symptoms of thyroid problems fatigue that is severe and getting worse depression, rapid heart rate, anxiety, shaking, nervousness sweating, nausea, diarrhea, vomiting losing hair, weight fluctuations and irregular menstrual cycles.

Common Sutent adverse effects could be:

• Indigestion, decreased appetite, stomach pain, nausea, vomiting, diarrhea;
• Being tired or weak;
• Mouth sores or pain, or a loss of perception of taste
• The appearance of blisters or a rash on your feet or hands;
• Bleeding or bruising;
• Higher blood pressure.

This isn't a complete list of all side effects. others could happen. Contact your physician to seek medical advice on the effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Sutent may cause serious heart issues. Your risk may be increased if you take other medications to treat asthma, infections or heart issues, high blood pressure, depression, mental illness, cancer, malaria or HIV. Sometimes, it's not advisable to use certain drugs at the same time. Some drugs can alter the blood levels and the other medications that you take, which can create side effects or render the medication less effective.

Inform your doctor about all other medications including:

• Osteoporosis medicine.

This list is not comprehensive. Other medications can be incompatible with sunitinib, such as medications that are prescribed and available over the counter, vitamins, and herbal supplements. Some interactions with drugs are not listed here. are included here.