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Generic name: articaine and epinephrine [AR-ti-kane-and-EP-i-NEF-rin]

Drug class: local injectable anesthetics

What is Septocaine?

Septocaine is an anesthetic (numbing medication). They block the transmission of nerve signals within your body.

Septocaine is a mixture of medicine that is used to numb your mouth during a tooth procedure.Septocaine can also be employed for other purposes that are not covered in this medication guide.

Side effects of Septocaine

See a doctor immediately. If you notice any of the following symptoms that indicate an allergic reaction, difficulty breathing, swelling, or puffiness on your lips, face, and tongue.

Inform your caregivers immediately in the event that you are suffering from:

  • Breathing that is shallow or weak;
  • A slower heartbeat;
  • An euphoric feeling, similar to you're passing out;
  • Blurred vision, sounds in your ears;
  • Anxiety or confusion, anxiety, tremors, or restlessness.

Contact your dentist or doctor immediately if there is any pain, swelling, or excessive bleeding following the procedure.

Common adverse consequences of Septocaine could include:

  • Tongue pain or swelling; gum swelling or redness;
  • Mild swelling of your face.
  • Headache
  • Numbness and tingling

This list does not constitute a comprehensive compilation of possible adverse reactions; more could occur. Contact your physician for advice regarding medical adverse effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.


You shouldn't take Septocaine in the event that you've experienced an allergic reaction to any kind of numbing medicine.

Prior to use this drug

It is recommended not to receive Septocaine in the event that you are allergic to any medication that numbs your body.

To be sure Septocaine is suitable for you, inform your doctor if:

  • A heart rhythm disorder
  • Blood pressure, and hypertension;
  • Asthma, an sulfur allergy,
  • A background of seizures

FDA classification for pregnancy C It isn't clear whether Septocaine could cause harm to a baby who is not yet born. Consult your physician if you are pregnant or plan to become pregnant while taking this medication.

It is unclear if articaine or epinephrine are absorbed through breast milk or whether they can harm the nursing infant. Consult your physician if you are nursing babies.

How to take Septocaine?

Septocaine is an injection that is typically in the gums within your mouth. The injection is administered in a dental clinic or in an oral surgical facility.

What happens if I miss the dose?

Because Septocaine is prescribed prior to dental procedures, you're not likely to be following a schedule of dosing.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact for help at the Poison Helpline at 1-800-222-1222.

Overdose symptoms can include severe tiredness, fainting or tremors (convulsions), breathlessness, or a sluggish heart rate.

What should be avoided?

The medication can cause numbness over a long period of time. Avoid chewing gum, eating food, or drinking hot beverages until the sensation in your mouth is completely restored. Chewing when your mouth isn't feeling as it should could result in a bite wound to your lips, tongue, or even inside your cheek.

Interaction with other drugs

Discuss with your physician any medications you are taking as well as the ones you begin or stop taking as you undergo treatment with Septocaine, particularly:

  • Antidepressant medicines--amitriptylline, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline and trimipramine--may help.
  • Antipsychotic medication: chlorpromazine, droperidol, fluphenazine, haloperidol, perphenazine,
  • MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine and others.

This list is not exhaustive. Other medications can react with epinephrine or articaine, which includes prescription and over-the-counter medications, vitamins, and herbal remedies. The interactions of all potential drugs are mentioned in this medication guide.