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Name of the generic: bupivacaine [bue-PIV-a-kane] Brand names: Marcaine hcl, Marcaine Spinal, Sensorcaine, Sensorcaine-MPF
Drug class: local injectable anesthetics

What is Sensorcaine-MPF?

Sensorcaine MPF is an anesthetic (numbing medicine) that acts as a local (in only one location) anesthetic.Sensorcaine-MPF will be provided by epidural infusion in the spinal column in order to cause numbness that can be felt during labor, surgery, or other medical procedures.Sensorcaine-MPF also serves as an anesthetic to aid in dental procedures.

Sensorcaine-MPF could be used to treat other conditions not covered in this medication guideline.

Side effects of Sensorcaine-MPF

Seek medical attention immediately. If you notice symptoms that indicate an allergic reaction, such as hives and bloody skin rash, itching or sneezing, breathing difficulty, and severe dizziness, vomiting or swelling of your lips, face, and tongue,

Contact your medical professionals immediately. If you suffer from one of the following serious adverse consequences:

  • Feeling anxious, agitated, and confused. You may feel dizzy, agitated, and drowsy, or you may feel like you could pass out.
  • Ringing in your ears, hearing loss, speech problems, or vision
  • A metallic taste in your mouth. Or a tingling sensation in your mouth
  • Muscle moving or tremors (convulsions);
  • Breathing that is shallow or weak;
  • Rapid heart rate, gasps, and feeling hot.
  • Slow heartbeat or weak pulse;
  • Very little or no urine.

Should you develop methemoglobinemia, seek medical help immediately. Signs and symptoms can include headaches and rapid heartbeats. Other symptoms include breathing problems, feeling tired or lightheaded, or a skin appearance that is light, gray, or blue-colored.

Common side effects are:

  • The weakness, persistent numbness, or tingling
  • Experiencing a feeling of drowsiness or restlessness;
  • Tremors;
  • Headache, blurred vision
  • Heartbeats that are slow or fast
  • Breathing issues;
  • Chills or shivering
  • Lower back pain
  • Nausea, vomiting.

This list does not represent all possible side effects; more could occur. Consult your physician for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.


Discuss with your doctor if you have ever experienced an allergy to any kind of numbing medication.

Certain epidural numbing medicines can cause long-lasting or permanent effects on some bodily functions, including sexual function, bowel and bladder control, and the sensation or movement of your feet or legs. Discuss with your physician the risk you face of nerve damage caused by Sensorcaine-MPF.

Prior to use this drug

Discuss with your physician. If you've had an allergy reaction to a particular type of numbing medication or if you've experienced:

  • Anemia (lack of red blood cells);
  • The kidneys or liver illness;
  • A bleeding or blood clotting disorder;
  • Syphilis Polio, syphilis, or a spinal cord tumor or brain
  • Tingling or numbness
  • Chronic backaches and headaches resulted from surgery.
  • Blood pressure, blood pressure, or excessive blood pressure;
  • An abnormal curvature of the spine;
  • Arthritis.

It is unclear if Sensorcaine-MPF harms the unborn baby. If you're not taking Sensorcaine-MPF for pregnancy, inform your doctor whether you are expecting.

It might not be safe to breastfeed while taking this medication. Inform your doctor of any potential risks.

How to take Sensorcaine-MPF?

Sensorcaine-MPF is injected via an injection needle directly into the area that is to be numbed. This injection is administered in a hospital or dental location.In the case of an epidural, sensorcaine MPF is injected via a needle that is inserted in the lower or middle back, close to your spine.Your blood pressure, breathing, oxygen levels, or any other vital signs will be closely monitored.

In a dental procedure, Sensorcaine-MPF injections are directly into the mouth, close to either the teeth or the tooth that your dentist is working on.Certain epidural drugs that cause numbness can cause long-lasting effects on specific bodily functions, including sexual function, bowel and bladder control, and movements or sensations in your feet or legs. Consult your physician regarding the risk you face of nerve damage resulting from Sensorcaine-MPF.

What happens if I miss the dose?

Because Sensorcaine-MPF is necessary prior to surgery or other dental treatment, you're unlikely to be on an exact schedule for dosing.

What happens if I overdose?

Since Sensorcaine MPF is administered in a medical environment, you'll be monitored carefully to ensure that you don't receive excessive amounts of Sensorcaine MPF. Should symptoms of overdose arise, caretakers will immediately intervene and treat you accordingly.

What should be avoided?

This medication can cause numbness across a large part of the body. After an epidural, you won't be capable of feeling or moving in your lower body. Make sure you avoid injuries as you remain in a state of numbness.

After undergoing a dental procedure, refrain from eating, chewing gum, or drinking hot beverages until your mouth isn't numb anymore.

Interaction with other drugs

Inform your physician about any other medications you take, including:

  • An antidepressant or antipsychotic medication;
  • Anti-nausea medication like Prochlorperazine (Compazine) or Promethazine (Phenergan);
  • Blood pressure medicine—carteolol, carvedilol, labetalol, nadolol, propranolol, sotalol, timolol;
  • A blood thinner like warfarin (Coumadin, Jantoven);
  • Ergot medicine—dihydroergotamine, ergotamine, ergonovine, methylergonovine;
  • An MAO inhibitor—isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

This list isn't complete. Other drugs can interact with Sensorcaine MPF, such as prescription and over-the-counter medications, vitamins, and herbal products. The interactions of all drugs are listed here.