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Bacitracin, neomycin, and polymyxin B (topical)

Generic names: bacitracin (topical), neomycin, and polymyxin-B (topical). [BAS-i-TRAY-sin], NEE-oh-MYE-sin [POL-ee-MIX-in-B]
Brand Names: Medi-Quik, Neosporin, Triple Antibiotic, Septa, Mycitracin Triple Antibiotic,…show all 8 brands
Topical ointment: 400 units-3.5 mg-5 000 units/g
Class of drugs: topical antibacterials

What is Bacitracin, neomycin, and polymyxin B (topical)?

Antibiotics kill bacteria on the skin by using bacitracin and neomycin.Combination medicine Bacitracin, Neomycin, and Polymyxin B Topical (for your skin) can be used to treat minor cuts or scrapes on the skin.This medication guide does not list all possible uses for neomycin and polymyxin B.

Side effects of Bacitracin, neomycin, and polymyxin B (topical)?

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, swelling of your lips, face, tongue, or throat.Hearing loss is a rare but serious side effect that has been reported in patients who have used other forms of Neomycin. This is not likely to happen if you absorb enough medicine through your skin. If you notice changes in your hearing, call your doctor immediately.If you notice severe redness, irritation, swelling, pus, oozing, or any other sign of infection, call your doctor immediately.

Some of the common side effects associated with bacitracin (neomycin), polymyxin B, and bacitracin include:

  • Itching, or mild
  • Minor irritation of the skin after taking a medicine

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Similar/related drugs

Bactrim, sulfamethoxazole, trimethoprim, tetracycline topical, Bacitracin topical, Bactrim DS, and Neosporin


Please read all the instructions on the label or package of your medication. Inform your healthcare provider about your medical conditions, allergies, and medicines.

Before you take this drug

This medication should not be used if you have an allergy to bacitracin or polymyxin-B.If you have any other medical conditions or concerns, ask your doctor or pharmacist whether it's safe to take the medicine.

  • Chronic ear infections are a common cause of chronic otitis.
  • A ruptured (torn) eardrum

Unborn babies may be harmed by bacitracin topical, neomycin, and polymyxin B. If you plan to get pregnant or are currently pregnant, tell your doctor.There is no way to know if bacitracin topical, neomycin, or polymyxin-B topical can pass into breast milk or if they could harm a baby who is nursing. You should tell your doctor if you're breastfeeding a child.It is not recommended to use topical neomycin or polymyxin B on children younger than 2 without consulting a doctor.

How to take Bacitracin, neomycin, and polymyxin B (topical)?

Do not exceed the recommended dosage or duration. Use the recommended dose and do not exceed it.To prepare the skin for application, you should wash it with soap and warm water. Then dry it completely.Apply the ointment sparingly. Use the ointment only on small cuts, animal bites, and serious burns. For instructions on treating these more serious skin injuries, contact your doctor.The medication can be used up to three times per day, or according to the instructions on the label. If desired, cover the wound with a bandage. Use a fresh bandage every time you apply medicine.Even if you feel better, continue to use the ointment as directed by the manufacturer or your doctor. You may see improvement in your symptoms before the infection has completely cleared.If your symptoms don't improve within 7 days or worsen while you are using bacitracin, neomycin, and polymyxin B topically, call your doctor.Store away from heat and moisture at room temperature. Do not use any ointment after the date of expiration printed on the medicine's label.

What happens if I miss the dose?

As soon as you recall, apply the missed doseIf your next dose is imminent, do not take the missed one. You should not take extra medicine to compensate for a missed dose.

What happens if I overdose?

Overdoses of bacitracin topical, neomycin, and polymyxin B are not dangerous. If anyone accidentally swallows the medication, seek emergency medical attention. Poison Help can also be reached at 1-800-222-1222.

What should be avoided?

Do not swallow. Use only the topical Bacitracin, Neomycin, and Polymyxin B on your skin. Do not get this medication in your nose, eyes, or mouth. If you do get it in your eyes, nose, or mouth, rinse immediately with water.Applying other skin care products, such as lotions, creams, ointments, or ointments that contain neomycin and polymyxin-B, to the same area you have treated with bacitracin is not recommended.

Interaction with other drug

Other drugs that you may take orally or even inject are unlikely to have any effect on bacitracin (topically applied), neomycin (topically applied), and polymyxin-B (topically applied). Many drugs interact with each other. Inform your healthcare providers of all the medicines you take, including prescriptions, over-the-counter medicines, vitamins, and herbal products.