The Web Health



Generically: Paroxetine paroxetine pa-ROX-a-teen
Drug Class: Selective serotonin reuptake inhibitors

What is Paxil?

Paxil is an antidepressant drug that is part of the class of medications known as selective serotonin reuptake inhibitors (SSRIs). Paroxetine alters the chemical balance within the brain, which could be imbalanced in those suffering from anxiety, depression, or any other disorder.Paxil can be used in the treatment of depression as well as major depressive disorder.

Paxil can also be utilized to treat anxiety disorders, obsessive-compulsive disorder (OCD), anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).


It is not recommended to use Paxil when you are already taking pimozide or thioridazine.Do not take Paxil in the 14-day period prior to or 14 days following the last time you took one of the MAO inhibitors, like linezolid or isocarboxazid. Also, avoid methylene blue injection or phenelzine, rasagiline, and selegiline. tranylcypromine.

Certain young people could contemplate suicide as they the first time they take an antidepressant. Be aware of fluctuations in mood and their symptoms. Be sure to report any new or worsening symptoms to your physician.

Take immediate medical attention when you notice symptoms that include hallucinations, agitation, or both. stiffness and twitching. You may also experience dizziness, loss of coordination, tingling or warmth, nausea, vomiting, fever, diarrhea, sweating, tremors, racing heartbeats, or seizures (convulsions).

Stop taking Paxil without consulting your physician.

Similar/related drugs

Rexulti, Trintellix, Sertraline, Trazodone, Escitalopram, Duloxetine, and Fluoxemic

Before you take this drug

It is not recommended to use Paxil if you're sensitive to paroxetine or if you're taking thioridazine or pimozide.

Do not take an MAO inhibitor for 14 days prior to or 14 days after taking paroxetine. A risky drug interaction may occur. MAO inhibitors are isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Once you have stopped taking Paxil, you must wait a minimum of 14 days before starting another MAO inhibitor.

To be sure Paxil is appropriate for you, speak to your physician if you are:

  • Heart disease, hypertension, or a stroke
  • Kidney or liver disease;
  • A bleeding or blood clotting disorder;
  • Seizures or epilepsy;
  • Bipolar disorder (manic depression), drug addiction, or suicidal thoughts;
  • Sexual problems;
  • Narrow-angle glaucoma;
  • The sodium levels are low in the blood.

Check with your physician whether you are also taking stimulant medicines, opioid medications, herbal products, or medications to treat mental illness, depression, Parkinson's disease, migraine headaches, serious infections, or the prevention of nausea or vomiting. These medications can be incompatible with paroxetine and can cause serotonin syndrome, a serious illness.

Certain young people could contemplate suicide as they the first time they take an antidepressant. The doctor you see will be able to monitor your condition regularly. Your family members and other caregivers should be on the lookout for changes in your symptoms or mood.

If you are taking an SSRI antidepressant, such as Paxil, during pregnancy, it could cause lung issues that are serious or other problems for the infant. You could also experience the possibility of relapses in depression should you discontinue using your antidepressant. Inform your doctor immediately if you become pregnant. Do not begin stopping or altering the dosage of this medication without consulting your doctor.

It is not recommended to use this medicine while breastfeeding.Paxil is not a drug that has been approved to be used by anyone younger than 18 years of age.

How to take Paxil?

Follow the exact dosage of Paxil prescribed by your physician. Follow all the instructions on the prescription label and go through all the medication guides or instructions. The doctor might alter your dosage.Suck the Paxil extended-release tablet intact. Do not crush, chew, or break the tablet.The Paxil suspension is shaken in the mouth (liquid) prior to taking a dosage. Utilize the dosing syringe that comes with it or use a dose-metering device (not the kitchen spoon).

It could take as long as four weeks before symptoms improve. Use the medication exactly according to the directions, and inform your physician if your symptoms don't improve.Talk to your doctor if you notice any changes in sexual activity, such as a loss of interest in sexual sex, having trouble with an orgasm, or (in males) issues with erections or ejaculation. Certain sexual issues are treatable.

Do not stop taking Paxil at once, or you may experience uncomfortable withdrawal effects. Consult your physician about how to completely stop using the medication. Follow the doctor's advice on the process of tapering your dose.Maintain at room temperature and free of heat, moisture, and light.

What happens If I miss a dose?

Do not take the medicine for as long as you are able, but avoid any missed doses if it's close to the time of the next dose. Don't take two doses at a time.

What happens if I overdose?

Get medical attention immediately or contact the Poison Help line at 1-800-222-1222. A paroxetine overdose can cause death.

What should be avoided?

Avoid driving or engaging in hazardous activities until you are aware of how the effects of paroxetine affect your body. The way you react could be impaired.

Talk to your doctor prior to taking a nonsteroidal antiinflammatory drug (NSAID) like ibuprofen, aspirin (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, and meloxicam, among others. When you take an NSAID together with Paxil, it could cause bleeding or bruises easily.

Consuming alcohol while taking this medication may cause unwanted side effects.

Side effects of Paxil

Contact a medical professional immediately. If you are experiencing symptoms warning of an allergy reaction to Paxil (hives, breathing difficulties, and swelling of your throat or face) or a severe reaction to your skin (fever or burning eyes, sore throat, and skin irritation, as well as red or purple skin that blisters and peels),

Inform your doctor about any new or deteriorating symptoms, like changes in your behavior or mood, anxiety, panic attacks, or trouble sleeping. You should also tell your doctor if you are angry, irritable, impulsive, aggressive, anxious, hyperactive (mentally and physically), depressed, or thinking about suicide or harming yourself.

Contact your doctor immediately. If you suffer from:

  • Racing thoughts, a decreased desire to sleep, unusual risk-taking behavior, a feeling of extreme happiness or sadness, or becoming more vocal than usual;
  • Blurred vision blurred vision, tunnel vision, eye swelling or pain, or halos appearing around lights;
  • Unusual bone pain, tenderness, swelling, or bruising
  • Fluctuations in weight or appetite;
  • Easily bruised, uncommon bleeding (nose, vagina, mouth, or the rectum), and coughing up blood;
  • Extreme nervous system reactions extremely rigid (rigid) muscles with high fever, sweating, confusion, rapid or irregular heartbeats, fainting,
  • Lower sodium levels in the body cause headaches and disorientation, significant weakness, loss of coordination, and feeling unsure.

You should seek medical attention now if you are experiencing symptoms of serotonin syndrome like hallucinations, agitation, sweating and shivering, high heart rate, stiff muscles, shaking, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects of Paxil include:

  • Vision change;
  • Weakness, drowsiness, dizziness, and tiredness;
  • Sweating, anxiety, shaking;
  • Sleep problems (insomnia);
  • Insomnia, loss of appetite diarrhea, vomiting, and constipation;
  • Dry mouth, yawning;
  • Infection;
  • Headaches migraine
  • Reduced sex drive insanity, abnormal ejaculation, or difficulty having an orgasm.

This isn't a complete list of possible side effects, and other side effects could occur. Consult your physician for advice regarding medical adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Utilizing Paxil along with other medicines that cause you to become drowsy could cause more drowsiness. Consult your physician before taking an opioid drug, a sleep pill, a muscle relaxer, or medication to treat seizures or anxiety.

Discuss with your doctor your other medications, particularly:

  • Cimetidine (Tagamet), digoxin, St. John's Wort, tamoxifen theophylline, tryptophan (sometimes called L-tryptophan), warfarin (Coumadin, Jantoven);
  • Diuretic, also known as a "water pill";
  • Heart rhythm medicine;
  • HIV, also known as AIDS medicines;
  • Certain medications for treating the symptoms of narcolepsy and ADHD, such as amphetamine, atomoxetine, dextroamphetamine, Adderall, Dexedrine, Evekeo, Vyvanse, and others;
  • Narcotic pain medicine (fentanyl, tramadol);
  • Medications to treat mood disorders, thought disorders, or mental illnesses, like lithium, buspirone, and other antidepressants or antipsychotics.
  • Migraine headache medication headache medication: sumatriptan, rizatriptan, zolmitriptan, and others;
  • Seizure medicine: phenobarbital and phenytoin.

This list is not comprehensive. Other drugs can be incompatible with paroxetine, such as prescription and over-the-counter medicines, vitamins, and herbal products. There are many possible interactions that are not mentioned in this medication guide.



Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories