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Generic name: collagenase topical [KOL-a-JEN-ase-TOP-ik-al]
Drug class: topical debriding agents

What is Santyl?

Santyl (for the face) is a treatment for serious skin ulcers or burns in adults. Santyl assists in removing dead skin tissue as well as aiding in healing wounds.Santyl can also be employed for other purposes that are not covered in this guideline.

Side effects of Santyl

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, like hives, trouble breathing, or swelling of your lips, face, and tongue.

Contact your physician immediately. If your skin condition becomes worse or if you experience new signs of disease or infection,More minor side effects might be more likely, and you could not experience any whatsoever.

This isn't a complete list of all the side effects. Other side effects could be present. Contact your doctor for advice regarding medical effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Only use it according to the directions. Inform your doctor if you take other medications or suffer from any other medical condition or allergies.

Prior to use this drug

It is not recommended to take Santyl if you have an allergy to it.Inform your doctor if you are breastfeeding or pregnant.

How to take Santyl?

Follow the directions on the prescription label and read the medication guide or instructions sheets. Make sure you use the medicine precisely as directed.Wash your hands thoroughly prior to or after applying Santyl.Follow your medical doctor's instructions on how to clean your skin wound and how to care for the dressing for the wound.

Santyl is typically applied once every day. It may be necessary to clean the wound before applying the ointment in the event that the area gets oily.Don't take care not to share Santyl with anyone else, even if they suffer from similar symptoms to yours.

The enzymes found in santyl could increase your chances of getting an infection in your bloodstream. Consult your physician right away when you experience fever, chills, rapid beats of the heart, vomiting, nausea, vomiting, diarrhea, or are feeling lightheaded or confused.Store at room temperature, away from heat and moisture. Make sure the tube is tightly sealed when it is not in use.

Similar or related drugs

Diclofenac topical, fluorouracil topical, imiquimod topical, Efudex, Collagenase Santyl, and Aldara

What happens if I miss the dose?

Take the medication as quickly as you can; however, do not take the missed dose if you think it is close to time for the next dose. Don't apply two doses at once.

What happens if I overdose?

A high dose of Santyl isn't likely to cause harm. If you believe you've taken too much of this medication, you can remove the enzyme using povidone iodine.

What should be avoided?

Do not use other medicines in the areas that you are treating with Santyl unless your doctor has told you to.

Interaction with other drugs

The skin-care products you take are unlikely to be influenced by any other medications you take. However, a variety of drugs may interact. Discuss with your doctor the medicines you take, including prescription and over-the-counter medications, vitamins, and herbal remedies.