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Promethazine

Name of the Generic: Promethazine (oral) (oral) pro-METH-a-zeen Promethazine (oral) [pro-METH-a zeen]
The Brand Name is Phenergan.
Drug Classes: Antihistamines, phenothiazine antiemetics

What is Promethazine?

Promethazine is in a group of drugs known as phenothiazines (FEEN-oh-THYE-a-zeens). It alters the chemical reactions within your brain. Promethazine can also function as an antihistamine. It reduces its effects by blocking the chemical histamine within your body.

Promethazine is a medication used to treat allergies like itching, nasal congestion, and sneezing. It can also treat itchy or dry eyes, hives, and rashes of the skin that are itchy. It also reduces motion sickness and treats nausea and vomiting as well as discomfort after surgery. It is also used to help with sleep or sedation. aid.Promethazine is not recommended to treat symptoms of pneumonia, asthma, or any other respiratory tract infections.

Warnings

Stop taking promethazine and contact your physician immediately in the event of twitching or uncontrollable movements in your lips, eyes, face, tongue, arms, or legs. These may be indications of harmful adverse effects. Promethazine should never be administered to children younger than two years old. Promethazine may cause breathing issues or even death in extremely young children. Follow the instructions of your physician when administering this medication to any child at any stage.

Promethazine may cause adverse effects that can affect your ability to think or react. Be cautious when driving or engaging in any activity that requires you to be conscious and awake. Beware of drinking alcohol, as it could increase certain negative effects of the drug. There are a myriad of other medicines that interfere with promethazine. Inform your doctor about any prescription or over-the-counter medicines you take. This includes minerals and vitamins, as well as herbal products and medicines prescribed by other doctors. Don't begin using any new medication without first talking to your physician. Keep a record of every medication you take and present the list to your physician or other health professional who cares for you.

Before you Take this Drug

Promethazine should never be administered to children younger than two years old. Promethazine may cause breathing issues or even death in infants and children who are very young. Be sure to follow your doctor's directions when administering this medicine to children at any stage of life.

It is not recommended to take this medicine if you are allergic to promethazine or similar medicines like mesoridazine, fluphenazine, chlorpromazine perphenazine, prochlorperazine, trifluoperazine, or thioridazine.

To make sure that promethazine is appropriate for you, consult your doctor if:

  • Asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, asthma, or any other breathing disorder.
  • A sulfite allergy;
  • A past of having seizures
  • An immune system that is weak (bone marrow depression);
  • Glaucoma;
  • An enlarged prostate or issues with urination
  • Stomach ulcers or obstructions;
  • High blood pressure or heart disease
  • Liver disease;
  • An adrenal gland tumor (pheochromocytoma);
  • The calcium levels are low in the blood (hypocalcemia), as well as
  • If you've had an adverse reaction that was serious during the use of promethazine or another phenothiazine,

It isn't known if promethazine can harm unborn babies. Inform your physician if you are expecting or planning to have a baby while taking this medication.

It isn't known if promethazine can be found in the milk of a nursing baby or whether it poses a risk to the nursing infant. Do not breastfeed when taking this medication.

How to take Promethazine?

Follow the exact dosage of promethazine as recommended by your physician. Follow the instructions on the prescription label. Your doctor may change the dosage to ensure you receive the most effective outcomes. Don't take this medication in smaller or larger doses or for a longer period than the recommended time.

Promethazine can be taken before bed or prior to meals. To prevent motion sickness, promethazine is typically initiated within an hour prior to travel. For surgery, it is typically administered the night prior to the procedure.

How often you will take this medication, as well as the timing of the dose, is going to be contingent on the condition that is being treated.Measure the amount of liquid medicine using the dosing syringe that comes with it or using a specially designed dosing spoon or medicine cup. If you do not own an instrument for measuring doses, you can ask your pharmacist for one.

If your child is taking this medicine, inform your physician if your child is experiencing any weight changes. Promethazine doses are determined by the weight of children, and any changes in weight could alter the dose for your child.Contact your physician if your symptoms don't improve or if they become worse when you take promethazine.

This medicine may cause abnormal results in certain tests. Inform any physician who treats your condition that you are taking promethazine.Maintain at room temperature, free of heat, moisture, and light.

What Happens If I Miss a Dose?

You should take the missed dose as quickly as you remember. Do not take your missed dose if you are nearing the time for the next dose. Don't take any extra medication to make up for the missed dose.

What Happens If I Overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.

The symptoms of an overdose can include hyperactive reflexes or a loss of coordination. extreme drowsiness or weakness, dilation of pupils, fainting, shallow or weak breathing, or seizures (convulsions).

What Should be Avoided?

This medication could impair your reactions or thinking. Be aware if you are driving or engaging in activities that require that you be aware. Be careful not to get up too fast from a lying or sitting position, as you could be shaky. Make sure to get up slowly and steadily to avoid falling.Drinking alcohol can intensify certain adverse effects of promethazine.

Avoid exposure to the sun and tanning beds. Promethazine can cause sunburn more quickly. Protect yourself with protective clothes and sunblock (SPF 30 or greater) while you're outdoors.

Side effects of Promethazine

Contact a medical professional immediately. If you experience any symptoms or warning signs like hives, trouble breathing, and swelling of your lips, face, and tongue,

Stop taking promethazine and contact your doctor immediately. If you suffer from:

  • Excessive drowsiness; deep or weak breathing;
  • A feeling of lightheadedness, as if you're about to pass out.
  • Confusion, agitation, hallucinations, and nightmares;
  • Seizure (convulsions);
  • Heartbeats that are slow or fast;
  • Jaundice (yellowing of the eyes or skin);
  • Muscles that are not controlled in your facial muscles (chewing or smacking your lips, mouth movement, frowning, blinking, or eye movements);
  • Bleeding or bruising (nosebleeds and bleeding gums);
  • A sudden feeling of weakness or discomfort such as chills, fever, sore throats, mouth sores, swelling, or red gums; difficulty swallowing;
  • Nervous system reactions that are severe, very rigid (rigid) muscles with high fever, sweating, and confusion, rapid or irregular heartbeats as if you're about to faint

The effects of side effects like extreme drowsiness and confusion could be more common in older adults.

Common side effects of promethazine include:

  • Drowsiness, dizziness;
  • Your ears are ringing.
  • Double vision double;
  • Feeling anxious;
  • Dry mouth dry mouth
  • Fatigue, insomnia (insomnia).

There isn't an exhaustive list of the possible consequences, but other effects might occur. Consult your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with Other Drugs

Medicines for colds or allergies such as sedatives, opioid pain medication, sleeping medication, muscle relaxers, and medicines for depression, seizures, or anxiety could interact with promethazine and create health problems or worsen adverse reactions. Consult your doctor if you frequently use any of these medications.

Tell your physician if you are taking any of these drugs:

  • Lithium (Eskalith, Lithobid);
  • Atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), and atropine (Atreza, Sal-Tropine), belladonna (Don (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), and scopolamine (Transderm-Scop);
  • Blood pressure medications like Guanadrel (Hylorel), Guanethidine (Ismelin), Propranolol (Inderal), and many other blood pressure medications;
  • A blood thinner like warfarin (Coumadin);
  • Bronchodilators, such as Ipratropium (Atrovent) as well as Tiotropium (Spiriva);
  • Medications for urinary or bladder problems like oxybutynin (Ditropan, Oxytrol), solifenacin (Vesicare), and many other medications;
  • An MAO inhibitor, such as isocarboxazid (Marplan), and an MAO inhibitor such as tranylcypromine (Parnate), phenelzine (Nardil), and selegiline (Eldepryl, Emsam); or
  • Treatments for the symptoms of Parkinson's disease and restless legs syndrome, pituitary gland tumors (prolactinoma), as well as
  • Medication to treat stomach ulcers or irritable bowel syndrome like dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin, and many others), mepenzolate (Cantil), and propantheline (Pro-Banthine).

This list isn't complete, and there are a variety of other medications that are incompatible with promethazine. Discuss with your doctor every prescription and non-prescription medicine, including minerals, vitamins, herbal products, and medications prescribed by your doctor. Do not begin an entirely new drug without consulting your doctor. Keep a record of the medications you take and present the list of medications to any doctor or health care provider who treats you.

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Prescription only

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