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Generic name: Tildrakizumab [ TIL-dra-KIZ-ue-mab ]
Drug class: Interleukin inhibitors

What is Ilumya?

Ilumya helps reduce any effects caused by a chemical in the body that may cause inflammation. Ilumya injection is a prescribed medicine that is used for treating moderate to severe psoriasis in adults who might benefit from pills, injections, or treatment with ultraviolet or phototherapy using UV light). Ilumya is also employed for other purposes that are not covered in this medication guide.


Ilumya alters the immune system. You could contract infections more frequently. Call your doctor in case you are suffering from chills, fever or aches, cough or breathlessness or skin sores, diarrhoea, weight loss or burning after you have to urinate.

Before taking this medication

You shouldn't be treated with Ilumya in case you are allergic to tildrakizumab. Consult your doctor if you are suffering from chronic infections or are due to get any vaccination. Inform your doctor if you have ever been diagnosed with tuberculosis or if anyone within your family is suffering from tuberculosis.

It isn't known if Ilumya could harm an unborn baby. Inform your doctor if you are expecting or planning to be pregnant. It might not be safe to breastfeed when you are taking tildrakizumab. Consult your physician about any risks. Ilumya is not permitted to be used by anyone younger than 18 years of age.

How to take Ilumya?

Ilumya can be administered as an injection beneath the skin (subcutaneous injection) within areas of your body, such as your stomach, thighs (abdomen) or your upper arm. A doctor will administer your Ilumya shot.

Before starting treatment with Ilumya Your doctor will run tests to confirm that you don't have tuberculosis or any other infections.

Details on dosage 

Usual Adult Dose of Ilumya for Plaque Psoriasis:

100 mg subcutaneously between Weeks 4 and 0 and then every 12 weeks thereafter.

Assess the patients' tuberculosis (TB) infection prior to initiating treatment.

Use: For people with moderate-to-severe plaque psoriasis, who could benefit from phototherapy or systemic therapy.

Administration guidance:
Ilumya should be administered only by a medical professional.
Before injection, remove the container from the refrigerator and then let the syringe prefilled (in the container with the lid shut) be at ambient temperature for 30 mins.
Follow the steps in the box to take out the prefilled syringe in a proper manner and only remove it when you are ready to inject. Do not remove the cover of the needle until you are ready.
Inspect the syringe for discoloration and particulate matter prior to administering. The solution is a clear to slightly opaque, colorless to somewhat yellow solution. Avoid using when the solution contains visible particles or if the syringe has been damaged. Air bubbles could be present, and there is no reason to get rid of them.
Select an injection location with clear skin and a simple access (such as the abdomen or thighs, or even the lower arm). Do not inject an injection of 2 inches in the area around your navel, or any area where the skin is swollen and swollen, erythematous or bruised. inflamed, or affected by Psoriasis. Avoid injecting into stretch marks, scars or blood vessels.
As you hold your syringe's body remove the needle cover off straight (do not twist it) and then discard.
Inject the entire amount (1 milliliters) to get 100 mg of the drug per Syringe.
Press down to the red plunger till the needle can be no longer. This will activate the safety mechanism to ensure complete retraction of the needle once the injection has been administered.
Remove the needle completely from the skin before releasing the plunger in blue. Once the blue plunger has been released, the safety lock will pull the needle into the guard.
If a dose is not taken, take the dose promptly after which you can resume taking the medication according to the regular interval.

What happens If I miss the dose?

If you do not attend an appointment to follow-up and do not receive the medication you should schedule a follow-up appointment the earliest is possible.

What happens If I overdose?

Get medical attention in an emergency or contact for help at the Poison Help line at 1-800-222-1222.

What should be avoided?

Don't receive a "live" vaccine while using Ilumya. The vaccine might not function in the same way and might not be able to fully protect you against illness. Live vaccines comprise measles Mumps, measles, rubella (MMR) as well as Typhoid, polio, and rotavirus varicella, yellow fever ( chickenpox) and Zoster ( shingles).

Side effects of Illumya

Take immediate medical attention If you are experiencing symptoms for an allergic reaction or irritation to Ilumya, such as Hives and breathing problems or swelling of your lips, face and tongue.

It is possible to contract infections more frequently, and even deadly or life-threatening illnesses. Call your doctor immediately if you show signs of infection like:

  • Fever, chills, sweating;
  • Skin sores;
  • Muscle pain;
  • An increase in urination, pain, or burning sensation when you urinate
  • Stomach pain, diarrhea, weight loss; or
  • Cough, breathlessness and coughing up red or pink mucus.

Common Ilumya adverse effects could include:

  • Itching, pain, rash swelling, redness, bleeding or bruising at the site of injection;
  • Diarrhea;
  • symptoms of cold like congestion,
  • Sneezing and a sore throat.

This isn't an exhaustive list of possible side effects, and others could happen. Consult your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Other drugs can interfere with tildrakizumab. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. Discuss with your doctor the medicines you are currently taking as well as any medications you are about to start or stop taking.