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Magnesium sulfate (injection)

Generic Name: Magnesium sulfate (injection) [ mag-NEE-see-um-SUL-fate].
Name of the Brand: Magnesium Sulfate Sodium Chloride Injection.
Dosage Forms: Injectable solution (50%), intravenous solution (1 g/100 mL-NaCl 0.9%; 1 g/50 mL-D5%; 1 g/50 mL-NaCl 0.9%; 10 mg/mL-D5%); 2 g/100 mL-D5%; 2 g/100 mL-NaCl 0.9%; 2 g/50 mL-NaCl 0.9%; 2 g/50 mL-sterile water; 20 g/500 mL-sterile water; 3 g added to NaCl 0.9% 50 mL; 4 g/100 mL-NaCl 0.9%; 4 g/100 mL-sterile water; 4 g/100 mL-sterile water; 40 g/1000 mL-sterile water; 40 mg/mL-LR; 6 g/100 mL-D5%; 6 g/50 mL-NaCl-NaCl-NaCl-D5%; 6 g/100 mL-D5%; 6 g/100 mL-D5%; 6 g/50 mL-D5%; 6 g/50 mL-NaCl-NaCl.
Classes of Drugs: Laxatives, minerals and electrolytes, and miscellaneous anticonvulsants.

What is Magnesium sulfate?

Magnesium is a natural mineral that plays a vital role in numerous systems within the body, particularly the nerves and muscles. Magnesium sulfate injections are utilized to cure hypermagnesemia (low amounts of magnesium present in the blood). Magnesium sulfate injections are also utilized to avoid seizures during pregnancy in women suffering from issues like pre-eclampsia, eclampsia, or toxemia associated with pregnancy. Magnesium sulfate injections can also be used to treat conditions that are not mentioned in this guide.

Side effects Magnesium sulfate injection

See a doctor immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as hives, difficulty breathing, and swelling of your lips, face, or tongue.

Contact your doctor immediately. If you suffer from:

  • Feeling like you might pass out.
  • Sweating, anxiety, and a cold feeling.
  • Flushing (warmth, redness, warmth, or tingling sensation).
  • Breath that is weak or shallow.
  • Extreme tiredness and feeling weak.
  • A tingling or numbness in your lips; tightness of muscles or contraction; excessive reflexes.

This isn't a complete list of possible adverse consequences, and others could happen. Consult your physician to seek medical advice on adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Similar or related drugs

Sabril, Clonazepam, Lamotrigine, Diazepam, Topiramate, Lamictal, and Klonopin


If you can, before receiving magnesium sulfate, ask your doctor if you have kidney problems, heart disease, stomach conditions, or are dehydrated. Also, inform your doctor if you consume alcohol or caffeinated drinks frequently, smoke, or use any of the street drugs.

Before you take this drug

Inform your physician whether you consume regular amounts of caffeine or alcohol and if you smoke or use drugs that are sold on the streets. These factors can alter the way magnesium sulfate is used in your body. If you can, before receiving magnesium sulfate, inform your doctor that you have:

  • kidney disease.
  • Heart disease.
  • A stomach or intestinal problem.
  • If you are dehydrated.

You shouldn't use magnesium sulfate when you are expecting. It could harm the unborn baby. Make sure you use efficient methods of birth control and inform your physician if you become pregnant while you are receiving treatment.

Magnesium sulfate may be absorbed into breast milk and can cause harm to a nursing infant. Don't use this medicine without discussing with your doctor whether you are breastfeeding. In an emergency, it is not always possible to inform your caregivers that you are expecting or breastfeeding. Be sure that any doctor who cares for your baby or your pregnant mother has been informed that you've taken this medication.

How to take Magnesium sulfate?

Magnesium sulfate is injected either into muscles or the vein via an IV. The injection will be administered in a hospital or clinic environment. Your blood pressure, breathing, oxygen levels, and other vital signs will be closely monitored during the time you receive magnesium sulfate.

What happens if I miss a dose?

Since magnesium sulfate can be prescribed by a doctor, you're not likely to skip the dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.

What should be avoided?

Follow your doctor's advice regarding any restrictions on your food, drink, or activity.

Interaction with other drugs

Discuss with your doctor the medicines you take and the ones you are about to start or stop using in the treatment you receive with magnesium sulfate, particularly the IV (injected) antibiotics.

Other medications can interfere with magnesium sulfate, such as prescription and non-prescription medicines, vitamins, and herbal products. Be sure to inform your health professionals about any medications you take now and any medications that you decide to stop or change your use of.