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Generic name: polyethylene glycol electrolyte solution [pall-ee-ETH-il-een-GLYE-kol-ee-LEK-troe-lyte]
Names of brands: GaviLyte-C With Lemon Flavor Pack GaviLyte-G with Lemon Flavor Pack GaviLyte-N with Flavor Packs GaviLyte-N With Flavor Packs, MoviPrep, etc. display each of the brands.
Drug class: laxatives

What is Plenvu?

Plenvu is a solution for laxatives that stimulates bowel movement. It also has minerals that replace electrolytes, which are eliminated from the body through the stool. Plenvu is used to cleanse the bowel prior to colonoscopy, barium x-ray, or other procedures to clean the intestinal tract. Plenvu can also be employed for reasons not mentioned in this guideline.

Side effects of Plenvu

See a doctor immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as hives, difficulty breathing, or swelling of your lips, face, and tongue.

Plenvu may cause serious side effects. Contact your doctor immediately. If you suffer from:

  • No bowel movements within 2 hours of the use;
  • Vomiting;
  • Dizziness, feeling like you might pass out;
  • Minimal or no urination
  • A seizure; or
  • Indications of an electrolyte imbalance: more thirst or urination, dry lips, and confusion. Constipation, muscle pain, or weakness the heartbeats of your legs are irregular, and leg cramps cause the sensation of tingling.

It is possible that you need to drink the liquid in a more gradual manner or stop drinking it for a brief period in case you experience specific negative side effects. Consult your physician for advice if you experience:

  • Gaging, choking, extreme stomach pain, or bloating;
  • Nausea nausea, vomiting headache, difficulty drinking liquids, or very little or no urine or
  • Fever, sudden or extreme stomach pain, extreme diarrhea, or rectal bleeding. Bright red stool movement.

Common adverse consequences of Plenvu include:

  • Vomiting, stomach pain, indigestion, bloating;
  • Discomfort or pain in the rectal area;
  • Craving, thirst, and slight nausea
  • Sleep problems sleep problems; or
  • Dizziness, chills.

This is not a comprehensive list of possible side effects, and other side effects could be present. Consult your physician for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.


Don't use Plenvu in the event of an intestine that is perforated, obstruction of the bowel, or severe constipation, as well as colitis and toxic megacolon. Plenvu may cause harmful or life-threatening adverse reactions in patients suffering from these conditions.

Before taking this medication

It is not recommended to use this medication if you have an allergy to polyethylene glycol or any other electrolyte solution (such as Pedialyte or Gatorade) or if you suffer from:

  • A perforated bowel
  • A bowel obstruction or a severe constipation
  • toxic megacolon or colitis.

Plenvu may cause hazardous or life-threatening adverse effects for patients suffering from these ailments.

People suffering from issues with eating (such as orexia or bulimia) shouldn't use this medication without consulting a medical professional.

Speak to your doctor if you have ever suffered from:

  • heart conditions, heart problems, or cardiac attack;
  • An electrolyte imbalance (such as low levels of sodium or potassium within your blood);
  • kidney disease;
  • a seizure;
  • gastroesophageal reflux disease (GERD), ulcerative colitis, and another stomach or bowel disease;
  • difficulties swallowing; trouble swallowing; aspiration (accidentally inhaling drinks or food);
  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency; or
  • an addiction to alcohol or drugs.

This medication may contain phenylalanine. Consult your physician prior to taking this medication if you suffer from the condition known as phenylketonuria (PKU).

How to take Plenvu?

Follow the directions on the label of your prescription and read the medication guide or instructions sheets. Make sure you use the medication exactly as prescribed.

The electrolyte powder of polyethylene glycol should be mixed to create an emulsion prior to using it. Don't mix in any flavorings like honey, sugar, artificial sweeteners, fruit juices, or any other drinks. Shake the mixture thoroughly just before measuring the amount. Drink your Plenvu in precisely measured portions at the exact intervals as prescribed by your physician. The medicine includes instructions regarding when and what to take or drink on your very first day. Every brand has different instructions.

Don't drink Plenvu when it's been less than an hour since your last solid food. For the best results, drink the medicine between 2 and 4 hours after the last time you consumed food. The first stool that is watery is expected to be visible within an hour following the time youstarted drinking Plenvu. Continue taking the medication until you've completed the prescribed doses by your physician.

Take lots of clear liquids (water or black coffee, broth, tea, and clear soda) prior to, during, and after taking this medication. Beware of foods and drinks that contain pulp or are purple or red in color. You may also consume popsicles (not fruit bars or fudge bars) or gelatin that is not flavored with the fruit or any toppings.

Avoid eating or drinking any food in the 2 hours preceding your colonoscopy or any other tests for medical purposes. The unmixed powder should be stored at ambient temperature, far from heat and moisture. The mixed solution should be stored in a refrigerator in an upright place.You should dispose of any Plenvu you've not used within 24 to 48 hours from the time the mixture was made (follow the directions specific to your type of medicine).

What happens if I miss a dose?

Speak to your doctor in the event that you are unable to consume all the medication recommended for you. The test or procedure might have to be changed when your bowel isn't completely cleaned.

What will happen if I take excessively?

For medical emergencies, seek emergency medical attention or contact for help at the Poison Help Line at 1-800-222-1222.

What should I be aware of when taking Plenvu?

Be sure to avoid taking any other medications, vitamins, or mineral supplements for at least one hour prior to drinking Plenvu. The cleansing of your bowels could make it difficult for your body's ability to take in any other medications you are taking by mouth. Do not take different laxatives when using Plenvu unless your physician has advised you to.

Interaction with other drugs

Discuss with your doctor any other medications you take, including:

  • Heart or blood pressure medication;
  • Diuretic, also known as a "water pill";
  • Medication to cure anxiety, depression, or mental illness
  • Treatments for kidney issues and low levels of sodium (hyponatremia);
  • Seizure medication; or
  • The nsaids (nonsteroidal anti-inflammatory drugs) are aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and many more.

This list isn't complete. Other medications can affect Plenvu, such as prescription and non-prescription medications, vitamins, and herbs. Some interactions with drugs are not listed here. are included here.